A5022249329- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Soil and Unsaturated Flow
- Geotechnical Engineering and Soil Stabilization
- Landfill Environmental Impact Studies
- Lung Cancer Treatments and Mutations
- Cloud Computing and Resource Management
- High-pressure geophysics and materials
- Geophysics and Gravity Measurements
- Cancer Immunotherapy and Biomarkers
- GNSS positioning and interference
- Advanced Database Systems and Queries
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Cancer-related cognitive impairment studies
- Galectins and Cancer Biology
- Dysphagia Assessment and Management
- Coastal wetland ecosystem dynamics
- Congenital Diaphragmatic Hernia Studies
- Berberine and alkaloids research
- Macrophage Migration Inhibitory Factor
- Caching and Content Delivery
- Cardiac Fibrosis and Remodeling
Henan Cancer Hospital
2019-2024
Zhengzhou University
2019-2024
Shantou University
2020-2024
Second Affiliated Hospital of Shantou University Medical College
2021-2024
Chang'an University
2022-2024
Meta (United States)
2023
Sun Yat-sen University
2022
LinkedIn (United States)
2018
Second Affiliated Hospital of Zhengzhou University
2014-2017
First Affiliated Hospital of Zhengzhou University
2016-2017
Abstract Recent studies on water retention behaviour of biochar amended soil rarely considers the effect pyrolysis temperature and also feedstock type into account. It is well known that influences physical chemical properties due to stagewise decomposition structure bonds. Further, density, which in a loose state (in agricultural applications) dense geo-environmental engineering can influence soils. The major objective this study investigate with three different biochars both state....
Organizations are often faced with the challenge of providing data management solutions for large, heterogenous datasets that may have different underlying and programming models. For example, a medical dataset unstructured text, relational data, time series waveforms imagery. Trying to fit such in single system can adverse performance efficiency effects. As part Intel Science Technology Center on Big Data, we developing polystore designed problems. BigDAWG (short Data Analytics Working...
Biochar has been used as an environment-friendly enhancer to improve the hydraulic properties (e.g. suction and water retention) of soil. However, variations in densities alter soil–biochar mix. Such density are observed agriculture (loosely compacted) engineering (densely applications. The influence biochar amendment on gas permeability soil barely investigated, especially for with different densities. major objective this study is investigate retention capacity, biochar-amended (BAS)...
Neoadjuvant chemotherapy (NAC) and neoadjuvant chemoradiotherapy (NACR) are the standard treatments for esophageal squamous cell carcinoma (ESCC). However, 5-year overall survival (OS) rate is still far from satisfactory. In recent years, immune checkpoint inhibitors (ICIs) have shown promising results in treatment of ESCC. More than 20 phase II clinical trials been launched to explore combinations ICIs setting Based on our trial, a two-arm III trial was Henan Cancer Hospital. combined with...
Evapotranspiration (ET) plays an important role in the hydrological cycle of river basins. Studying ET Yellow River Basin (YRB) is greatly significant for scientific management water resources. Here, we made full use advantages Gravity Recovery and Climate Experiment (GRACE) GRACE Follow-On (GRACE-FO) gravity satellites monitoring large-scale changes to calculate terrestrial storage anomaly (TWSA) flux YRB from May 2002 June 2020. Furthermore, combined with flux, precipitation, runoff data,...
Abstract Esophageal squamous cell carcinoma (ESCC) is highly heterogeneous. Our understanding of full molecular and immune landscape ESCC remains limited, hindering the development personalised therapeutic strategies. To address this, we perform genomic-transcriptomic characterizations AI-aided histopathological image analysis 120 Chinese patients. Here show that can be categorized into differentiated, metabolic, immunogenic stemness subtypes based on bulk single-cell RNA-seq, each...
Esophageal squamous cell carcinoma (ESCC) occurs with highest frequency in China over 90% mortality, highlighting the need for early detection and improved treatment strategies. We aimed to identify ESCC cancer predisposition gene(s). Our study included 4,517 individuals. The discovery phase using whole‐exome sequencing (WES) 186 familial patients from high‐risk China. Targeted gene validation of 598 genes 3,289 Henan 1,228 moderate‐risk Hong Kong Chinese. A WES approach identified BRCA2...
Pulmonary fibrosis is a scarring disease of lung tissue, which seriously threatens human health. Treatment options are currently limited, and effective strategies still lacking. In the present study, 25 compounds were isolated from deep-sea fungus Trichoderma sp. MCCC 3A01244. Among them, two β-carboline alkaloids, trichocarbolines A (1) C (4) new compounds. The chemical structures these elucidated based on their HRESIMS, 1D 2D NMR spectra, optical rotation calculation, comparisons with data...
The phosphorylated epidermal growth factor receptor (P-EGFR) and Akt (P-Akt) protein in esophageal squamous cell carcinoma (ESCC) were studied, its significance clinical prognosis of patients was assessed. expression P-EGFR P-Akt 83 cases ESCC normal tissues determined by immunohistochemical staining. Log-rank test correlation analysis used to analyze the ESCC. positive 88% (73/83 cases) compared with 41% mucosa (34/83 (P<0.05). rate 90.4% (75/83 cases), 27.7% seen (23/83 positively...
North China (NC) is experiencing significant groundwater depletion. We used GRACE and GRACE-FO RL06 Level-2 data with Mascon from April 2002 to July 2022. fused these two types of through the generalized three-cornered hat method further combined them hydrological models, precipitation, in situ groundwater-level, extraction (GWE) determine verify temporal spatial variations storage (GWS) NC. quantitatively assessed sustainability by constructing a index explored dynamic cyclic process change...
<h3>Objective:</h3> There are no comprehensive studies on survival outcomes and optimal treatment protocols for cervical esophageal cancer (CEC), due to its rare clinical prevalence. Our objective was determine the relationship between pathological characteristics, protocols, in Chinese CEC patients. <h3>Methods:</h3> A total of 500 patients were selected from our 500,000 gastric cardia carcinoma database (1973–2018). two main groups: treated with surgery, receiving non-surgical treatments...
While genetic alterations in several regulators of the cell cycle have a significant impact on gastric carcinogenesis process, prognostic role them remains to be further elucidated. The TCGA-STAD training set were downloaded and mRNA expression matrix genes was extracted corrected for analysis after taking intersection with GSE84437 dataset. Differentially expressed mRNAs identified between tumor normal tissue samples TCGA-STAD. Univariate Cox regression lasso model established novel...
Thorough investigations using Raman spectra of solid methane (CH${}_{4}$) were conducted moissanite anvil cells in the range 1$\ensuremath{-}$43 GPa at room temperature to identify high-pressure phases. Two interesting phases uncovered, one with a narrow pressure 1 centered around 12.5 and another 3 40.5 GPa. Our results do not support existence phase transformation 25 The high-quality spectra, obtained by single-crystal samples, boundaries seven pressures up 43.2
BigDAWG is a polystore database system designed to work with heterogenous data that may be stored in disparate and storage engines. A central component of the ability submit queries executed different This paper presents monitoring framework for BigDawg federated which maintains performance information on benchmark queries. As environmental conditions change, updates existing match current conditions. Using this information, can determine optimal query execution plan similar incoming We also...
Abstract Biochar amended soil (BAS) is widely studied to apply in green infrastructure, such as landfills and slopes. Presence of biochar improved hydraulic properties (e.g. water retention ability) previous studies, while influence on gas permeability (k g ) under different compaction states not clear yet. The main objective this study investigate the k BAS conditions. selected for investigation was poorly graded sand. compacted an in-house built 1-D column set up three density (65 %, 80 %...
Abstract Background Neoadjuvant therapy plus oesophagectomy has been accepted as the standard treatment for patients with potentially curable locally advanced oesophageal cancer. No completed randomized controlled trial (RCT) directly compared neoadjuvant chemotherapy and chemoradiation in squamous cell carcinoma (ESCC). The aim of current RCT is to investigate impact surgery chemoradiotherapy on overall survival resectable ESCC. Methods This open label, single-centre, phase III (cT2-T4aN +...
Background Studies about the influence of weekday esophagectomy on survival are limited and show conflicting results. This study aimed to explore whether affects patient's outcomes. Methods Patients who underwent in a grade-A tertiary hospital from January 2015 December 2016 were enrolled. The primary outcome was 5-year overall (OS). secondary outcomes disease-free (DFS) days hospitalization. impact surgery OS DFS evaluated with Cox regression, its hospitalization assessed using logistic...