A5014588918- Veterinary Oncology Research
- Infectious Diseases and Mycology
- Microbial infections and disease research
- Immunotherapy and Immune Responses
- Veterinary Equine Medical Research
- Liver Disease Diagnosis and Treatment
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- T-cell and B-cell Immunology
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Chemokine receptors and signaling
- Gastric Cancer Management and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Drug Transport and Resistance Mechanisms
- Virus-based gene therapy research
- Immune Response and Inflammation
- Gastrointestinal motility and disorders
- Gastroesophageal reflux and treatments
- Venous Thromboembolism Diagnosis and Management
- Tumors and Oncological Cases
- Cell Adhesion Molecules Research
- Intestinal and Peritoneal Adhesions
- Tracheal and airway disorders
Japan Small Animal Medical Center
2024
The University of Tokyo
2012-2021
Colorado State University
2021
Veterinary Medical Center
2015-2020
University of Veterinary Medicine
2012
Kagoshima University
2005-2006
Gastrointestinal eosinophilic sclerosing fibroplasia (GESF) in cats presents as mass(es) associated with the gastrointestinal tract, mesentery, and abdominal lymph nodes.
Little information is available on the relationship between computed tomography ( CT ) imaging findings and pathologic diagnosis of canine hepatic tumors. Our purpose was to clarify characteristic features in liver tumors dogs. Data from 33 dogs with either a hepatocellular carcinoma, n = 14, adenoma, or nodular hyperplasia, 5 were summarized medical records. for each histologic characterized analyzed statistically. Common carcinoma included central (79%, P 0.0030) marginal enhancement (93%,...
Biliary sludge in dogs is dismissed commonly as an incidental finding. On the other hand, gallbladder mucocele reported increasingly and can lead to biliary obstruction or rupture. Cholestasis suspected play a role development of mucoceles, though there are no data support this. We investigated emptying, key factor flow, with mobile sludge, immobile healthy controls. Gallbladder ejection fraction estimated by ultrasonography was used index emptying. The at 60 min after eating significantly...
The present study was carried out to analyze the prognosis of 163 cats with lymphoma classified anatomically and cytomorphologically. Anatomically, alimentary most common form showed significantly shorter survival than mediastinal nasal lymphomas in cats. Cytomorphologically, there no predominant subtype feline lymphomas. Immunoblastic type (18%), centroblastic (16%), globule leukocyte (15%), lymphocytic (12%), lymphoblastic pleomorphic medium large cell (10%) anaplastic (7%) were relatively...
Canine histiocytic sarcoma (HS) is a rare neoplasm that originates from dendritic cells or macrophages, and there have been number of cases experienced in Japan. To identify the characteristics prognostic variables determine outcome dogs with HS Japan, medical records 73 were retrospectively analyzed. Signalment, clinical signs, complete blood count (CBC), chemistry profiles, treatment, response to treatment overall survival (OS) Diagnosis was determined histologically 44 cytologically 29...
Canine pancreatitis is a relatively common disorder, and its mortality rate remains high. However, prognostic factors for based on evidence are limited. Moreover, the relationship between changes in C-reactive protein (CRP) concentration-an important factor human patients with acute pancreatitis-and prognosis of dogs has not been widely studied. Therefore, we examined canine during first medical examination evaluated usefulness serial CRP measurements hospitalization. Sixty-five met...
Medical records of dogs with colorectal polyps were retrospectively reviewed, and clinical presentation inflammatory in miniature dachshunds was evaluated. Of 33 found to have polyps, markedly over-represented 16 (48%), which 12 (75%) polyps. Multiple localized between the rectum descending colon most common finding Twenty (80%) out 25 responded immunosuppressive therapy using prednisolone cyclosporine. The results this study indicate that are predisposed develop multiple for may be a...
Background Although immunoglobulin A (IgA) plays a key role in regulating gut homeostasis, its canine inflammatory bowel disease ( IBD ) is unknown. Hypothesis IgA expression may be altered dogs with , unlike that observed healthy and other gastrointestinal diseases. Animals Thirty‐seven 10 intestinal lymphoma, 20 dogs. Methods Prospective study. IgG concentrations serum, feces, duodenal samples were measured by ELISA. + cells lamina propria CD21 peripheral blood mononuclear PBMC s) examined...
The effectiveness of combination therapy using clindamycin, metronidazole and doxycycline against canine babesiosis, the usefulness platelet count plasma C-reactive protein (CRP) concentration as an estimation factor for treatment, were evaluated in four dogs experimentally infected with Babesia gibsoni. successfully eliminated B. gibsoni peripheral blood 3 4 dogs, however remaining dog showed obvious uncontrolled relapse after a temporary recovery. In addition, it was shown that CRP levels...
Little information is available regarding triple-phase computed tomography (CT) of canine pancreatic insulinoma. A few case reports with small numbers cases have indicated that hyper-attenuation in the arterial phase was a common finding on multi-phasic CT dogs Our purpose to clarify characteristic findings insulinoma CT. Nine underwent were included present study. Attenuation patterns hypo-attenuation 4 and 2 cases. In remaining 3 cases, 1 showed phase, presented later phase. Altogether, 5...
Abstract OBJCTIVE To investigate the effects of dietary lipid overload on bile acid metabolism and gallbladder motility in healthy dogs. ANIMALS 7 Beagles. PROCEDURES In a crossover study, dogs were fed high-fat–high-cholesterol diet (HFCD) or low-fat (LFD) for period 2 weeks. After 4-month washout period, other Before at end each feeding concentrations acids, cholecystokinin (CCK)-induced motility, metabolism–related hepatic gene expression examined all RESULTS The HFCD significantly...
ABSTRACT Background Whereas non‐ Helicobacter pylori helicobacters, which are frequently detected in the stomachs of dogs and cats as a source zoonoses, have attracted considerable attention, role pets H. epidemiology is unclear. In our previous study, an infection was stomach dog (Dog 1). Here, we investigated status female offspring Dog 1 2) its owner within same household. Materials Methods Biopsy specimens were obtained from dog's tested for . DNA gastric biopsy samples 1, fluid sediment...
Canine alimentary lymphoma is currently diagnosed on the basis of findings cytological or histopathological examination. However, it often difficult to histopathologically distinguish from lymphocytic-plasmacytic enteritis. Recently, application polymerase chain reaction for antigen receptor gene rearrangement (PARR) has been reported. In present study, we assess sensitivity PARR analysis in diagnosing canine using endoscopically obtained biopsy specimens 12 dogs that were as having...
High-mobility group box 1 (HMGB1), a nonhistone chromosomal protein, has recently been suggested as late mediator of the inflammatory cascade. Blood HMGB1 levels are increased in number human diseases, and to be useful marker for disease severity prognosis. The objective this study was assess clinical usefulness dogs. Plasma levels, well C-reactive protein (CRP), typical canine marker, were measured dogs with various especially systemic response syndrome (SIRS), that had undergone surgery....
Inflammatory colorectal polyp (ICRP), common in miniature dachshunds, presents with hematochezia, tenesmus and mucoid feces. Although an 80% response rate has been reported when treated prednisolone cyclosporine, effective treatment is needed for the remaining 20% of ICRP dogs. Leflunomide immunosuppressive drug as several immune-mediated diseases. In present study, we retrospectively evaluated efficacy adverse effects leflunomide 15 dogs that were refractory to cyclosporine. Treatment was...
Although cytology is a rapid diagnostic procedure in dogs, the cytologic criteria of endoscopic biopsies for chronic enteritis and intestinal lymphoma are not well defined. An immediate diagnosis using would benefit patients by enabling prompt initiation therapy. The objective this study was to investigate correlation between results histopathology. In study, 167 dogs with clinical signs gastrointestinal disease were included. On basis histopathology, following diagnoses determined:...