A5030527407- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Radiopharmaceutical Chemistry and Applications
- Cancer, Lipids, and Metabolism
- Bladder and Urothelial Cancer Treatments
- Pediatric Urology and Nephrology Studies
- Hepatitis B Virus Studies
- Renal and Vascular Pathologies
- Hormonal and reproductive studies
- Acute Myeloid Leukemia Research
- Multiple Myeloma Research and Treatments
- Lung Cancer Treatments and Mutations
- Economic and Financial Impacts of Cancer
- Renal and related cancers
- Hepatitis C virus research
- Neutropenia and Cancer Infections
- Inflammatory Biomarkers in Disease Prognosis
- Viral-associated cancers and disorders
- Frailty in Older Adults
- Pregnancy and preeclampsia studies
- Histone Deacetylase Inhibitors Research
- Testicular diseases and treatments
- Effects of Radiation Exposure
- Neuroendocrine Tumor Research Advances
Kaohsiung Medical University
2024-2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2024-2025
National Yang Ming Chiao Tung University
2021-2024
Taichung Veterans General Hospital
2021-2024
LinkedIn (United States)
2023
Essen University Hospital
2021-2022
German Cancer Research Center
2021
University of Oslo
2017
I-Shou University
2011-2016
E-Da Hospital
2011-2016
Abstract Several life‐prolonging therapies for metastatic castration‐resistant prostate cancer (mCRPC) are available, including radium‐223 dichloride ( 223 Ra), which was approved based on phase 3 data demonstrating improved overall survival (OS) and a favorable safety profile. To date, real‐world evidence Ra use in Taiwan is from three studies of <50 patients. This observational study (NCT04232761) enrolled male patients with histologically/cytologically confirmed mCRPC bone metastases...
Background: Sexual dysfunction is common after radical prostatectomy (RP). Although pelvic-floor muscle exercise (PFME) has been recommended for sexual dysfunction, the optimal time starting exercises this surgery and effects of still need to be examined. Objectives: The present study was intended explore prevalence assess efficacy PFME in following RP. Methods: Participants were randomly distributed into an experimental group (n = 35) or a control 27). took part as regular daily activities...
Purpose: To investigate the prognostic efficacy of Geriatric Nutritional Risk Index (GNRI) in patients with metastatic Castration–resistant Prostate Cancer (mCRPC) receiving docetaxel as first line treatment. Methods: We retrospectively reviewed mCRPC and Taichung Veterans General Hospital from 2006 to 2012. The GNRI was calculated using serum albumin body mass index, a poor nutritional status defined &lt;92.0. Multivariate Cox-regression analysis used evaluate risk survival. Results:...
Background/Aim: Prostate cancer (PCa) is lethal. Our aim in this retrospective cohort study was to use machine learning-based methodology predict PCa risk patients with benign prostate hyperplasia (BPH), identify potential factors, and optimize predictive performance. Patients Methods: The dataset extracted from a clinical information database of at single institute January 2000 December 2020. newly diagnosed BPH prescribed alpha blockers/5-alpha-reductase inhibitors were enrolled. excluded...
Aims and objectives. To evaluate the symptoms self‐assessment of quality life in men with localised prostate cancer after having had a radical prostatectomy or brachytherapy treatment. Background. Prostate is significant growing disease among Taiwan. Quality issues for who are living this consequences Design. A postal questionnaire survey. Methods. The study population came from one 1170‐bed hospital Kaohsiung County, Data was collected 20 August 2007–20 November 2009. Seventy‐eight met...
Background/Aim: The use of complete metastasectomy for treating metastatic renal cell carcinoma (mRCC) has been shown to improve survival outcomes in the era tyrosine kinase inhibitors (TKIs). However, its effectiveness combination with immune checkpoint (ICIs) remains unclear. Therefore, objective study was elucidate impact patients mRCC who received both TKIs or ICIs. Patients and Methods: A total 157 diagnosed between 2006 2018 Taichung Veterans General Hospital were included study....
RENAL nephrometry score (RNS) has been proposed as an anatomical classification system for renal masses to investigate the influence on perioperative outcomes and complications. The aim of this study was assess external validation laparoscopic partial nephrectomy (LPN). single-surgeon database enrolled patients who had undergone LPN from December 2008 September 2013. Renal tumors were divided into low-, intermediate-, high-complexity groups according RNS sum score. We reviewed including...
Docetaxel has been widely used in metastatic Castration-resistant Prostate Cancer (mCRPC) patients for decades. The purpose of the study was to evaluate efficacy docetaxel rechallenge with mCRPC.We retrospectively compared who had received either first-line and after Androgen Receptor-axis Targeted therapies (ARAT), those without docetaxel. Multivariate cox-regression analysis survival.Out 204 mCRPC enrolled study, 24 180 did not. median overall survival 50.11 months group, as 26.36...
The aim of this study was to investigate whether complete cycles Radium-223 (Ra-223) improved survival in patients with metastatic castration resistant prostate cancer (mCRPC).We retrospectively analyzed mCRPC treated Ra-223 at Taichung Veterans General hospital. Patient and disease characteristics, laboratory results, number bone metastases, treatment sequence, outcomes were collected. Overall progression-free (PFS) Kaplan-Meier analysis. Uni- multivariate analysis used identify...
The clinical hazard of prostate cancer development after five-alpha reductase inhibitors (5ARI) treatment among benign hyperplasia (BPH) patients is still controversial. aim this study was to evaluate the epidemiological features BPH treated in a single institute identify risk factors associated with development.We retrospectively analyzed who were diagnosed and received alpha blockers (AB) only or 5ARI between January 2007 December 2012 followed up until death 2020. primary outcome...
You have accessJournal of UrologyInfections/Inflammation/Cystic Disease the Genitourinary Tract: Kidney & Bladder II (PD63)1 May 2024PD63-05 DECODING THE INTRICACIES OF CHRONIC KIDNEY DISEASE: EXPLORING GTF21 POLYMORPHISMS AS POTENTIAL BIOMARKERS IN A COLLABORATIVE MULTICENTRIC CROSS-SECTIONAL STUDY Kevin Lu, Kun-Yuan Chiu, I-Chieh Chen, Guan-Cheng Lin, Jian-Ri Li, and Chen-Li Cheng LuKevin Lu , ChiuKun-Yuan Chiu ChenI-Chieh Chen LinGuan-Cheng Lin LiJian-Ri Li ChengChen-Li View All Author...
Key Points Genetic factors are key players in CKD, with two linked single-nucleotide polymorphisms the GTF2I gene, associated CKD susceptibility Taiwanese population. Individuals specific genotypes (CT/TT for rs117026326 and CT/CC rs73366469) show higher prevalence earlier onset. Men of rs73366469 face a heightened risk compared women, particularly at lower eGFR. Background poses global health challenge, but its molecular mechanisms poorly understood. play critical role, phenome-wide...
Granulocyte transfusions have long been used to bridge the time neutrophil recovery in patients with neutropenia and severe infection. Recent randomized controlled trials did not prove a beneficial effect of granulocyte transfusions, but were likely underpowered suffered from very heterogeneous study populations.We retrospectively reviewed data all treated at our pediatric center 2004 2019. To identify parameters that predict success we stratified 3 groups. Patients group 1 cleared their...
Novel hormone agents (NHA) have become important tools for the treatment of advanced prostate cancer. Among them, abiraterone and enzalutamide are two major regimens in metastatic castration-resistant cancer (MCRPC). The aim this study was to evaluate efficacy both drugs patients who had disease progression after androgen deprivation therapy (ADT), using our real-world database.We retrospectively analyzed MCRPC received between October 2010 2021. associations baseline demographics clinical...