A5101878424- Cancer-related molecular mechanisms research
- Photosynthetic Processes and Mechanisms
- RNA modifications and cancer
- Circular RNAs in diseases
- Light effects on plants
- Plant Diversity and Evolution
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- Plant Molecular Biology Research
- Algal biology and biofuel production
- Advanced biosensing and bioanalysis techniques
- Antioxidant Activity and Oxidative Stress
- Extracellular vesicles in disease
- Plant Stress Responses and Tolerance
- Inflammatory Biomarkers in Disease Prognosis
- Plant Gene Expression Analysis
- Innovative Educational Techniques
- Cancer-related gene regulation
- Effects and risks of endocrine disrupting chemicals
- Delphi Technique in Research
- Hedgehog Signaling Pathway Studies
- Natural product bioactivities and synthesis
- Alcohol Consumption and Health Effects
- Gout, Hyperuricemia, Uric Acid
- Dental Research and COVID-19
China Agricultural University
2012-2024
Hunan University of Traditional Chinese Medicine
2023-2024
Guangxi Medical University
2022-2024
First Affiliated Hospital of GuangXi Medical University
2022-2024
Wuxi People's Hospital
2011-2024
Tianjin Academy of Agricultural Sciences
2024
Xian Yang Central Hospital
2024
University of Toronto
2020-2022
Potato Research Institute
2021
Sichuan University
2021
ABSTRACT Triclosan (TCS) and triclocarban (TCC), as broad spectrum antibacterial agents, are distributed widely in the environment humans. Most studies have focused on their distribution biodegradation, but endocrine‐disrupting effects of these chemicals, especially estrogenic effects, still unclear. In present study, we investigated TCS TCC using a series vitro assays, including ER reporter gene assay CV‐1 cells, E‐screen evaluation estrogen‐responsive genes MCF‐7 cells. The tested...
The current paper investigates how long non-coding RNA (lncRNA) FAM83A antisense 1 (lncRNA FAM83A-AS1) affected the epithelial-mesenchymal transformation (EMT), growth, invasion and migration of lung adenocarcinoma (LUAD) via targeting miRNA-141-3p. GEPIA ENCORI databases were used to analyze differences in lncRNA FAM83A-AS1 levels within LUAD samples. miR-141-3p assessed using qRT-PCR among 30 samples surrounding normal tissues. In addition, we analyzed proliferation, invasion, migration,...
Hepatocellular carcinoma (HCC) is a fatal disease with great public health impact worldwide. Heme oxygenase (HO)-1 has recently been reported as an important player in tumor angiogenesis and metastasis. However, the role of HO-1 liver cancer metastasis unclear. In this study, we explored genetic differences downstream signal transduction pathways cell lines. wild-type mutant lines were generated from human line HepG2. The overexpression decreased migration HepG2 cells. contrast, HO-1G143H...
Low light stress is one of the most important factors affecting photosynthesis and growth in winter production cucumber (Cucumis sativus L.) solar greenhouses northern China. Here, two genotypes (Deltastar Jinyan 2) are used to determine effect low on Rubisco expression leaves from emergence senescence. During leaf development, net photosynthetic rate (PN), stomatal conductance (gs), initial activity activation state, transcript levels rbcL rbcS, abundance rbcS DNA these increase rapidly...
Rheumatoid arthritis (RA) is an inflammatory disease that leads to disability; however, existing therapies are still unsatisfactory. Activated fibroblast-like synoviocytes (FLSs) play essential role in synovitis formation and joint destruction RA. The Hedgehog signaling pathway aberrantly activated contributes the aggressive phenotype of RA-FLSs. However, it remains uncertain whether inhibiting Smoothened (SMO), a critical component pathway, effective treatment for Here, we design series...
Lung cancer is a high incidence on worldwide basis and has become major public health problem. adenocarcinoma (LUAD) makes up approximately half of all lung cancers threat to human health. Long non-coding RNAs (lncRNAs) an important regulator the development progression adenocarcinoma. In this manuscript we examined role potential mechanism lncRNA PCAT6 in LUAD.Differences levels between LUAD samples normal were first explored GEPIA database. We found that expression was elevated, which also...
Violaxanthin de-epoxidase (VDE) plays an important role in protecting the photosynthetic apparatus from photo-damage by dissipating excessively absorbed light energy as heat, via conversion of violaxanthin (V) to intermediate product antheraxanthin (A) and final zeaxanthin (Z) under high stress. We have cloned a gene (CsVDE) cucumber. The amino acid sequence CsVDE has homology with VDEs other plants. RT-PCR analysis histochemical staining show that is expressed all green tissues cucumber...
Background: Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 1 (NEDD1) serves as a crucial factor in promoting cellular mitosis by directly facilitating wheel assembly and daughter centriole biogenesis at the lateral site of parent centrioles, ultimately driving centrosome replication.The amplification centrosomes abnormal expression centrosome-associated proteins contribute to invasion metastasis non-small cell lung cancer cells.However, specific mechanism which NEDD1...
Triple-negative breast cancer (TNBC) is a common with high aggressiveness and mortality in women. Recently, plenty of studies have indicated that long non-coding RNAs (lncRNAs) exert the crucial function human cancers, TNBC included. The carcinogenicity lncRNA intergenic non-protein coding RNA 1503 (LINC01503) has been confirmed several nevertheless, its still unclear. Therefore, our study aimed to reveal underlying mechanism LINC01503 TNBC.
Long non-coding RNAs (lncRNAs) play a crucial role in tumor generation and progression. However, the exact functional significance underlying molecular mechanism by which lncRNA CERS6-AS1 operates context of lung adenocarcinoma (LUAD) remain unknown. We aimed to evaluate potential CERS6-AS1/miR-424-5p/ANLN axis progression LUAD through bioinformatics cytobehavioral experiments, provide new insight into combined treatment LUAD. Based on TCGA database, expression pan-cancer was evaluated, its...
Abstract Background Photosynthesis in the green leafless blade tissues or organs of plants has been studied some plants, but photosynthetic characteristics stems and petioles are poorly understood. Cucurbitaceous climbing that have substantial stem petiole biomass. Understanding contribution cucumber to their growth underlying molecular mechanisms important for regulating production. Results In this study, capacity were determined by 14 CO 2 uptake. The total carbon fixed was approximately...
Objective To investigate the DNA methylation status of promoter region within coding gene hsa-miR-124a in human gastric cancer tissue, and examine its association with expression Rb CDK6 protein clinicopathological factors. Methods Methylation-specific PCR (MS-PCR) was used to detect tissues adjacent normal from 30 patients. The these examined using immunohistochemistry. Results overall rate 73.3%, which significantly higher than that (10.0%, P＜0.05). positive rates were 86.7% 80.0%,...
Objective To evaluate the diagnostic performance of plasma miR-499 in acute myocardial infarction (AMI) diagnosis. Methods Diagnostic accuracy test.The suspected AMI patients,who with chest pain for more than half an hour and been admitted Second People′s Hospital Wuxi First chuzhou during October 2010 July 2011,were consecutively prospectively enrolled present study.Sixty apparently healthy individuals were designed as control.The samples patients collected within two hours after...
Abstract The xanthophyll cycle is crucial for protecting plants and algae from photodamage. While the resistance of violaxanthin de-epoxidase enzyme (VDE) to high-light stress in has been extensively studied, there limited knowledge about VDE-related (VDR) proteins, which share a close homologous relationship with VDEs. In this study, we conducted preliminary investigation VDR protein aspects basic bioinformatics, spatiotemporal gene expression patterns, strong light treatment. Through...