A5083846211- Genetic Neurodegenerative Diseases
- Epilepsy research and treatment
- Mitochondrial Function and Pathology
- Dementia and Cognitive Impairment Research
- Neurological disorders and treatments
- Attention Deficit Hyperactivity Disorder
- Traumatic Brain Injury Research
- Neuroscience, Education and Cognitive Function
- Neurobiology of Language and Bilingualism
- Cognitive Abilities and Testing
- Psychological Testing and Assessment
- EEG and Brain-Computer Interfaces
- Psychotherapy Techniques and Applications
- Children's Physical and Motor Development
- Stroke Rehabilitation and Recovery
- Paranormal Experiences and Beliefs
- Cerebral Palsy and Movement Disorders
- Personality Disorders and Psychopathology
- Telemedicine and Telehealth Implementation
- Cognitive Functions and Memory
- Aging and Gerontology Research
- Hemispheric Asymmetry in Neuroscience
- Patient Satisfaction in Healthcare
- Healthcare Policy and Management
- Traumatic Brain Injury and Neurovascular Disturbances
University of Iowa
2010-2023
University of Iowa Hospitals and Clinics
2019-2023
Johns Hopkins University
2019
University of Virginia
2006
Nova Southeastern University
2001-2002
Austin Peay State University
2000
To assess brain morphometry in a sample of patients with juvenile-onset Huntington disease (JOHD) and several mouse models (HD) that likely represent the human JOHD phenotype.
The primary aim of this paper is to accelerate the number randomized experimental studies reliability and validity in-home tele-neuropsychological testing (tele-np-t).
Improve data-driven research to inform clinical decision-making with pediatric epilepsy surgery patients by expanding the Pediatric Epilepsy Research Consortium Surgery (PERC-Surgery) Workgroup include neuropsychological data. This article reports on process and initial success of this effort characterizes cognitive functioning largest multi-site cohort in United States.Pediatric neuropsychologists from 18 institutions completed surveys regarding practice impact involvement collaborative....
Aim: The symptoms of Huntington's disease are well known, yet the juvenile (JHD) less established due to its rarity. study examined a cluster considered be common, but under-recognized in JHD: pain, itching, sleeping difficulties, psychosis and tics. Materials & methods: A symptom survey was constructed using online tool Qualtrics dispersed JHD caregivers through websites. Results: total 33 surveys were completed. Disrupted sleep most prevalent (87%), followed by tics (78%), pain (69%),...
Abstract Background Juvenile‐onset Huntington's disease (JOHD) is a rare form of (HD) characterized by symptom onset before the age 21 years. Observational data in this cohort lacking. Objectives Quantify measures progression for use clinical trials patients with JOHD. Methods Participants who received motor diagnosis HD were included Kids‐JOHD study. The comparator group consisted children and young adults at‐risk inheriting genetic mutation that causes HD, but found to have CAG repeat...
Cognitive changes have been reported in patients after electroconvulsive therapy (ECT), but few studies investigated post-ECT across multiple cognitive domains. Because dysfunction is presumed to be more salient psychotic depression, we propose a brief pre-ECT multidomain assessment battery, assessing neurocognitive function this population before and ECT. We also compared performance estimated premorbid levels determined if neuropsychological functioning was related symptom...
Reports of behavioral disturbance in Juvenile-Onset Huntington’s Disease (JOHD) have been based primarily on qualitative caregiver reports or retrospective medical record reviews. This study aims to quantify differences behavior patients with JOHD using informant- and self-report questionnaires. Informants 21 children/young adults (12 female) 115 (64 a family history Disease, but who did not inherit the disease themselves (Gene-Non-Expanded; GNE) completed Behavior Rating Inventory Executive...
This study investigates the relationship between death anxiety and denial scale scores of persons employed in death-risk (DRG), death-exposure (DEG), or low-risk (CG) occupations. Participants were active duty military health care providers college students (CG). Death instruments selected Hoelter's Multidimensional Fear Scale (MFODS) Templer's Anxiety (DAS). Spielberger's Rationality/Emotional Defensiveness (R/ED) was measure. The two scales positively correlated ( p = .001). There no...
The purpose of the study was to examine relationship between Luria-Nebraska Neuropsychological Battery-Third Edition (LNNB-III) and Wechsler Adult Intelligence Scale-Third (WAIS-III). Participants were 85 adults referred for neuropsychological evaluation. mean age participants 38.73 years (SD = 16.54) average education 13.07 2.60). sample predominantly female (52.9%), right-handed (86.3%), Caucasian (68.6%), with remainder population classified as Hispanic (13.7%), African-American (5.9%),...
The number of older adults in America is increasing every year, and just over one decade, people aged 65 will surpass the children under age 18 for first time history. Along with aging comes increase prevalence cognitive impairment because primary risk factor neurodegenerative conditions such as Alzheimer disease related disorders. There an urgent need to identify early possible so interventions can be deployed reduce associated medical, behavioral, economic burden on patients, families,...
The primary aim of this paper is to review evidence and clinical implications related lifestyle activities associated with promoting brain cognitive health. Our targets four key factors: physical activity exercise, social engagement, cognitively stimulating activity, consuming Mediterranean-style diets.
Previous studies have found that injury rates are slightly higher in children who play flag football versus tackle football. It is unclear if this difference due to the way each type played or taught whether there intrinsic differences attitudes neuropsychological characteristics and their parents.To determine score differently from those on validated tests.Cross-sectional study; Level of evidence, 3.Each participating athlete (aged 8-12 years) was recruited 2018 2019 by email through local...
This study assesses the interrater reliability of revised Advanced Psychodiagnostic Interpretation (API) scoring system for Bender Gestalt Test (BGT). The API identifies 207 possible distortions in a BGT protocol. Agreement across nine raters exceeded 90% each three clinical protocols. Kappa statistics indicated that exhibited good reliability. Further research is necessary such areas as test-retest and validity to further demonstrate effectiveness procedure.
This study assesses the test-retest reliability of revised Advanced Psychodiagnostic Interpretation (API) scoring system for Bender Gestalt Test (BGT). The API identifies 207 possible distortions in a BGT protocol. Test-retest 40 schizophrenic patients tested twice with mean interval 6.4 years (SD=3.8 years) was good, ranging from .71 to .80. Further and validity studies are needed further demonstrate effectiveness system.
CASE: Brian is an 11-year-old boy who presented to the emergency room with suicidal ideation and hearing voices. In preceding weeks, he had escalating symptoms of oppositional defiant disorder, attention-deficit hyperactivity disorder (ADHD), bipolar disorder. His medical history was notable for complex partial epilepsy onset at age 4 that been well controlled divalproate. He several mental health diagnoses by various practitioners including ADHD, Brian's family social absence identifiable...
Objective: The paper describes the case of a 27-year-old, right-handed woman, KF, who sustained left thalamic ischemic infarct. KF's is unusual in that she presented with ipsilateral hemiparesis. No similar cases were found existing literature. Young-Mok et al. (2005) describe two hemiparesis following corona radiata infarct they attribute to re-organization brain previous right-sided supratentorial stroke; however, there no radiologic evidence prior stroke for KF. Method: KF reported on...
Objective: The COVID-19 pandemic significantly disrupted schools and learning formats. Children with epilepsy are at-risk for generalized academic difficulties. We investigated the potential impact of on in those by comparing achievement well-established measures among school-age children referred prior to during pandemic. Participants Methods: This study included 466 [52% male, predominately White (76%), MAge=10.75 years] enrolled Pediatric Epilepsy Research Consortium (PERC) Surgery...
Objective: The Pediatric Epilepsy Research Consortium (PERC) Surgery Database Project is a multisite collaborative that includes neuropsychological evaluations of children presenting for epilepsy surgery. There some evidence specific phenotypes within (Hermann et al, 2016); however, this less clear in pediatric patients. As first step, we applied an empirically-based subtyping approach to determine if there were profiles using indices from the Wechsler scales [Verbal IQ (VIQ), Nonverbal...
Objective: Pediatric patients with frontal lobe epilepsy (FLE) have higher rates of attention deficit hyperactivity disorder (ADHD), as well executive functioning (EF) and fine motor (FM) challenges. Relations between these constructs been established in youth ADHD are supported by FM EF skill involvement frontal-subcortical systems. Still, they not understood pediatric FLE. We hypothesized that poorer performance would be related to greater dysfunction symptomatology this group....