A5001104716- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Pediatric Pain Management Techniques
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Neurobiology of Language and Bilingualism
- Infant Health and Development
- Hemoglobinopathies and Related Disorders
- Childhood Cancer Survivors' Quality of Life
- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- Attention Deficit Hyperactivity Disorder
- Pregnancy and Medication Impact
- Child and Adolescent Psychosocial and Emotional Development
- Advanced Chemical Sensor Technologies
- Fetal and Pediatric Neurological Disorders
- Olfactory and Sensory Function Studies
- Advanced Neuroimaging Techniques and Applications
- Cardiac Arrest and Resuscitation
- Meningioma and schwannoma management
- Neuroscience of respiration and sleep
- Sleep and related disorders
- Pain Management and Placebo Effect
- Mental Health Research Topics
- Congenital heart defects research
Emory University
2020-2024
Children's Healthcare of Atlanta
2010-2024
NeuroDevelopment Center
2021-2023
Boston Children's Hospital
2015-2020
Harvard University
2020
Capital District Health Authority
2015
Georgia State University
2010-2012
During pregnancy in women with epilepsy, lower blood concentrations of antiseizure medications can have adverse clinical consequences.
Background: To date, few studies have delineated clear sex-based differences in symptom resolution after a sports-related concussion (SRC), and equivocal results been identified on baseline assessments. Purpose: assess whether female athletes displayed prolonged recovery more symptoms at an SRC compared with male athletes. Study Design: Cohort study; Level of evidence, 3. Methods: The current study assessed 135 41 (10-18 years old) who participated high-impact sports metropolitan Atlanta...
Data suggest parents' preprocedural anxiety is related to children's acute procedural and pain. This study examined the temporal relations among these constructs determine whether mediates relation between anticipatory pain.A total of 90 preschoolers receiving immunizations, their parents, nurses rated Parents provided ratings own anxiety.Bootstrapping analyses revealed that mediated pain according report nurses' but not self-report pain.Analyses Thus, targeting might be beneficial parents...
<h3>Importance</h3> The neurodevelopmental risks of fetal exposure are uncertain for many antiseizure medications (ASMs). <h3>Objective</h3> To compare children at 2 years age who were born to women with epilepsy (WWE) vs healthy and assess the association maximum ASM in third trimester subsequent cognitive abilities among WWE. <h3>Design, Setting, Participants</h3> Maternal Outcomes Neurodevelopmental Effects Antiepileptic Drugs (MONEAD) study is a prospective, observational, multicenter...
Improve data-driven research to inform clinical decision-making with pediatric epilepsy surgery patients by expanding the Pediatric Epilepsy Research Consortium Surgery (PERC-Surgery) Workgroup include neuropsychological data. This article reports on process and initial success of this effort characterizes cognitive functioning largest multi-site cohort in United States.Pediatric neuropsychologists from 18 institutions completed surveys regarding practice impact involvement collaborative....
INTRODUCTION: Hemispherectomy is an important surgical technique for seizure control. METHODS: Between 2019 to 2023, 65 sEEGs, 11 functional hemispherectomy surgeries were carried out in the authors’ institution. All patients had at least a one-year follow up. Four who fulfilled standard criteria underwent sEEG investigation. four also vEEG, MRI, PET, and neuropsychological studies. One patient MEG study. RESULTS: Patients’ age ranged from 10 16 years epilepsy etiologies related neonatal...
<h3>BACKGROUND AND PURPOSE:</h3> Ischemic injury to the brain is a common complication of SCA. To better understand neurologic impact SCA, TBSS were applied DTI data investigate white matter injuries in pediatric patients with <h3>MATERIALS METHODS:</h3> comparisons range anisotropy and diffusion measures carried out between age- background-matched population groups: SCA no visible lesions, mild gliosis, normal controls. <h3>RESULTS:</h3> analysis revealed that both populations exhibited...
The association of fetal exposure to antiseizure medications (ASMs) with outcomes in childhood are not well delineated.
Objective To examine a computerized parent training program, "Bear Essentials," to improve parents' knowledge and coaching help relieve preschoolers' immunization distress. Method In randomized controlled trial, 90 parent–child dyads received Bear Essentials plus distraction, distraction only, or control. Outcomes were knowledge, child behavior, pain. Results resulted in improved of the effects reassurance, provision information, apologizing on children's procedural Trained parents also...
Abstract The conventional intracarotid amobarbital (Wada) test has been used to assess memory function in patients being considered for temporal lobe epilepsy (TLE) surgery. Minimally invasive approaches that target the medial (MTL) and spare neocortex are increasingly used, but a knowledge gap remains how language risk from these procedures. We retrospectively compared results of two versions Wada test, artery (ICA-Wada) posterior cerebral (PCA-Wada) approaches, with respect predicting...
We present neuropsychological and functional outcome data in a teenager undergoing stereotactic laser amygdalohippocampotomy (SLAH) who had drug-resistant mesial temporal lobe epilepsy due to left hippocampal sclerosis. Given strong baseline cognitive performance, there was concern for post-operative declines language verbal memory were this patient undergo open resection. She evaluated pre- post-ablation with clinical experimental measures including semantic memory, category-specific...
The piriform cortex (PC) is part of the olfactory system, principally receiving input from lateral tract and projecting to downstream components network, including amygdala. Based on preclinical studies, PC vulnerable injury can be easily kindled as an onset site for seizures. While role in human epilepsy has been studied indirectly subject speculation, cases demonstrated seizure direct intracranial recording are rare. We present a pediatric patient with drug-resistant focal reflex right...
Functional abdominal pain (FAP) is a common physical complaint in children and adolescents. Prior research has documented associations between FAP symptoms mood, especially internalizing behaviors. Limited available examining the association symptom burden cognitive function this pediatric population. This study explored symptoms, behaviors, school Twenty-seven participants (mean age = 12.6 years, range 8.8-16.5; 33% male) diagnosed with completed assessments of cognitive, emotional,...
Many studies have investigated brain network dynamics involved in language, but most done so from the scalp and focused on discrete components of language. Functional mapping using stereoelectroencephalography (SEEG) offers a unique opportunity to directly examine eloquent cortex supporting Picture naming is common task used during SEEG map language may not adequately capture neural “natural” everyday conversation. In this exploratory case report, we high-frequency activity (HFA)...
Accurate assessment of pain severity is important for caring patients with sickle cell disease (SCD). The Brief Pain Inventory was developed to address limitations previous pain-rating metrics and available in a short form (BPI-SF). However, the BPI-SF self-report scale dependent on patient comprehension interpretation items.
Pathogenic variants in SPTAN1 result abnormal neurodevelopment but limited information is available on the spectrum of neurodevelopmental profiles associated with variations this gene. We present novel data collected at two time points over a three-year period nine-year-old patient heterozygous de novo variant, drug-resistant epilepsy, and left hippocampal sclerosis. Across evaluations, our patient's performance was highly variable, ranging from below age expectation to within age-expected...
Abstract Objective This pilot study examines the effects of yoga therapy on anxiety, depression symptoms, inattention, and seizure frequency in children diagnosed with Epilepsy. Data Selection The sample consisted 5 participants (4 male, 1 female), ages 7-12 years old, diagnoses generalized epilepsy, absence complex partial epilepsy. Participants all had average cognitive abilities (IQ SS = 100.7; VCI 106.3; PRI 108.3), a diagnosis Attention Deficit Hyperactivity Disorder (ADHD), clinically...