- Forest, Soil, and Plant Ecology in China
- GABA and Rice Research
- Genetic Mapping and Diversity in Plants and Animals
- Rice Cultivation and Yield Improvement
- Plant Ecology and Soil Science
- Ecology and Conservation Studies
- Plant Stress Responses and Tolerance
- Multiple Myeloma Research and Treatments
- Plant Molecular Biology Research
- Plant Pathogens and Fungal Diseases
- Plant Diversity and Evolution
- Plant responses to water stress
- Photosynthetic Processes and Mechanisms
- Protein Degradation and Inhibitors
- Plant Gene Expression Analysis
- Plant tissue culture and regeneration
- Horticultural and Viticultural Research
- Ginger and Zingiberaceae research
- Plant Physiology and Cultivation Studies
- Plant Reproductive Biology
- Environmental and Agricultural Sciences
- Gestational Diabetes Research and Management
- CAR-T cell therapy research
- Liver physiology and pathology
- Pregnancy and preeclampsia studies
Shanghai Changzheng Hospital
2021-2024
Tianjin Children's Hospital
2020-2024
Southern Medical University
2023-2024
Guangdong Provincial People's Hospital
2021-2024
Guangdong Academy of Medical Sciences
2021-2024
Hunan University of Arts and Science
2024
Innovation Team (China)
2024
Hebei Agricultural University
2024
Jiangxi Academy of Agricultural Sciences
2017-2023
Rice Research Institute
2016-2022
Significance De-repressing appendage growth induces development of ectopic wings on the dorsal prothorax (T1) neopteran insect Oncopeltus . These T1 wings, albeit fully developed, are small and primarily origin. Transcriptome data indicate that incorporation ventrally originating tissue was a key evolutionary innovation for generating large useful T2 T3 wings. Complimentary functional experiments reveal an adjacent thoracic plate not developmentally distinct structures, coregulated to create...
This study aimed to investigate the effects of Se-enriched probiotics (SP) on liver fibrosis induced by CCl4 in rats. The results showed that SP significantly decreased serum alanine aminotransferase (87.0 ± 1.96 U/L), aspartate (101 3.13 hepatic hydroxyproline (898 72.5 μg/g), and malondialdehyde (2.39 0.34 nmol/mg) levels, but increased glutathione peroxidase (37.2 3.19 U/mg), superoxide dismutase (201 19.2 levels (3.32 0.25 mg/g) (P < 0.05) rats treated CCl4. suppressed inflammation...
Abstract Ethylene response factor (ERF) Group VII members generally function in regulating plant growth and development, abiotic stress responses, immunity Arabidopsis; however, the details of regulatory mechanism by which ERFs mediate immune responses remain elusive. Here, we characterized one such member, ERF72, as a positive regulator that mediates resistance to necrotrophic pathogen Botrytis cinerea. Compared with wild-type (WT), erf72 mutant showed lower camalexin concentration was more...
Patients with high-risk newly diagnosed multiple myeloma (NDMM) often have poor outcomes standard treatments, necessitating novel effective frontline therapies to enhance clinical outcomes. GC012F, a B-cell maturation antigen/CD19 dual-targeting chimeric antigen receptor (CAR) T-cell therapy, has been developed on the FasTCAR platform. Notably, its use as therapy for patients NDMM who are eligible transplant not thoroughly explored.
The prevalence of hyperuricemia (HUA) and gout continues to increase in China. Research suggests that HUA may be related many diseases other than gout. However, further population research is required investigate the association between metabolic syndromes. This study sought an average China, serum uric acid (UA) levels disorders.This multicenter retrospective real-world examined hospital information system data 4 tertiary hospitals 3 provinces patients aged 18 80 years, who had attended at...
Several studies have found that a low baseline -density lipoprotein cholesterol (LDL-C) concentration was associated with poor prognosis in patients acute coronary syndrome (ACS), which is called the "cholesterol paradox". Low LDL-C may reflect underlying malnutrition, strongly increased mortality. The aim of this study to investigate paradox CAD and effects malnutrition.A total 41,229 admitted Guangdong Provincial People's Hospital China were included from January 2007 December 2018 divided...
Chlorophyll content is one of the most important traits controlling crop biomass and economic yield in rice. Here, we isolated a spontaneous rice mutant named thermo-sensitive chlorophyll deficit 1 (tscd1) derived from backcross recombinant inbred line population. tscd1 plants grown normally seedling to tiller stages showed yellow leaves with reduced content, but no significant differences after booting stage. At temperatures below 22°C, obvious yellowish phenotype. With increasing...
Summary This open‐label, prospective trial evaluated the combination of ixazomib, cyclophosphamide and dexamethasone (ICD) in 12 newly diagnosed POEMS syndrome patients. The study is registered with Chinese Clinical Trials Registry (ChiCTR2000030072). treatment protocol consisted cycles ICD regimen compromising ixazomib (4 mg on Days 1, 8 15), oral (300 15) (20 weekly). A total patients received a median 10 (range: 3–23) regimen. haematological response could be overall rate was 80% (8/10),...
Recent findings have suggested that oxidative damage might contribute to the cytotoxicity and carcinogenicity of aflatoxin B1 (AFB1). Salvia miltiorrhiza (Sm), a herbal plant has been used extensively in traditional Chinese medicine for treating cardiovascular liver diseases, is believed some antioxidative capabilities. In this study, protective effect Sm against AFB1-induced was investigated cultured primary rat hepatocytes. lipid peroxidation (LPO) were estimated by determination lactate...
Abstract Seed aging is the key factor leading to loss of genetic integrity. In this study, seeds Dongxiang wild rice, Xianggu, 9194 and Nipponbare were kept in a plant incubator with constant temperature humidity for artificial treatment. The integrity germplasm resources different germination gradients analyzed using 44 SSR markers. results suggested that accessions could be ranked order resistance from highest lowest as common rice > Xianggu Nipponbare. maintain diversity population...
<em>Melastoma dodecandrum</em> Lour. (MDL) is component used in traditional Chinese medicine that widely distributed throughout southern China. MDL has been long utilized clinical treatment for various conditions, such as inflammation. However, the toxicity and underlying anti‑inflammatory mechanism of remain to be elucidated. In present study, Sprague‑Dawley rats received intragastric administration 2 months, was investigated. The were treated with lipopolysaccharide (LPS) 8 h determine...
Abstract Background High-sensitivity C-reactive protein (hs-CRP) plays an important role in hypoalbuminemia as a representative of inflammation, which is closely associated with poor prognosis among patients coronary artery disease (CAD). The present study aimed to evaluate the independent and joint effects high hs-CRP levels on long-term mortality CAD patients. Methods A total 1449 were included from prospective, multicenter, observational cohort (REICIN, NCT01402232) referred for...
Abstract Serum B-cell maturation antigen (sBCMA) levels can serve as a sensitive biomarker in multiple myeloma (MM). In the research setting, sBCMA be accurately detected by enzyme-linked immunosorbent assay (ELISA), but approach has not been approved for clinical use. Here, we used novel chemiluminescence method to assess 759 serum samples from 17 healthy donors and 443 patients with plasma cell (PC) diseases including AL amyloidosis, POEMS syndrome, MM. BCMA were elevated 16.1-fold newly...
Lately, numerous researches have portrayed stress hyperglycemia ratio (SHR) is predominantly connected with short-term adverse prognosis among individuals who acute coronary syndrome. Nevertheless, the relation of SHR prolonged effects and value in predicting artery disease (CAD) patients or lacking chronic kidney (CKD) remain unclear. The present study was designed to elucidate long-term all-cause cardiovascular death CAD CKD non-CKD.
Seed storability (SS) is an important trait for agronomic production and germplasm preservation in rice (Oryza sativa L.). Quantitative locus (QTL) seed three storage periods was identified using two sets of recombinant inbred lines (RILs) derived from the crosses with a common female parent Shennong 265 (SN265). Ten QTLs were detected on chromosomes 1, 2, 3, 4, 6, 8, 12 SL-RILs (SN265/Lijiangxingtuanheigui (LTH)), total 9, 10 SH-RILs (SN265/Luhui 99 (LH99)) different periods. Among these...
Grain traits are major constraints in rice production, which key factors determining grain yield and market values. This study used two recombinant inbred line (RIL) populations, RIL-JJ (japonica/japonica) RIL-IJ (indica/japonica) derived from the crosses Shennong 265/Lijiangxintuanheigu (SN265/LTH) 265/Luhui 99 (SN265/LH99). Sixty-eight quantitative trait loci (QTLs) associated with 10 were consistently detected on 12 chromosomes across different populations environments. Although 61.75% of...
Although application of calcium polyamino acid (Ca-polyAA) is one the effective ways to improve saline-alkali soil and promote plant growth, clear mechanisms are unknown. A two-year field experiment with four Ca-polyAA treatments (added at rates 0, 7.5, 15.0, 22.5 × 103 kg ha−1) was conducted on in Songnen Plain China. In first year (2016), increased porosity decreased pH, electrical conductivity (EC1:5) exchangeable sodium percentage (ESP). Root Na+/K+ Na+/Ca2+ ratio were reduced whereas...
Abstract A recombinant inbred line ( RIL ) population consisting of 153 lines derived from a cross between indica ‘Zhongyouzao8’ and japonica ‘Toyonishiki’ rice was used to detect stable quantitative trait loci QTL for rapid visco analyser RVA characteristics under four environmental conditions. We identified 93 profiles, pleiotropic regions harbouring stably expressed were detected on chromosomes 2, 6, 7 11. These newly will facilitate further research into the genetic mechanism regulating...