A5080600976- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Computational Drug Discovery Methods
- Cancer Immunotherapy and Biomarkers
- Health Systems, Economic Evaluations, Quality of Life
- Pancreatic and Hepatic Oncology Research
- Fashion and Cultural Textiles
- Lung Cancer Treatments and Mutations
- Ferroptosis and cancer prognosis
- Healthcare Policy and Management
- interferon and immune responses
- Immune Response and Inflammation
- Chinese history and philosophy
- Electromagnetic Fields and Biological Effects
- Pancreatic function and diabetes
- Dental Education, Practice, Research
- Pharmacological Effects of Natural Compounds
- Cardiovascular Health and Risk Factors
- Renal cell carcinoma treatment
- Cancer Risks and Factors
- Nutritional Studies and Diet
- Diverse Scientific Research Studies
- Dental Health and Care Utilization
- Ideological and Political Education
- Global Health Care Issues
Beijing Radiation Center
2023-2025
Tianjin Medical University
2023-2024
Shanxi Normal University
2024
Jiangxi Institute Of Economic Administraors
2020-2024
Liaoning Technical University
2024
Shanxi University of Finance and Economics
2007-2024
Huawei Technologies (China)
2020-2024
Sichuan University
2023
Shaanxi Normal University
2023
Union Hospital
2020-2023
Abstract To unravel the source of SARS-CoV-2 introduction and pattern its spreading evolution in United Arab Emirates, we conducted meta-transcriptome sequencing 1,067 nasopharyngeal swab samples collected between May 9th Jun 29th, 2020 during first peak local COVID-19 epidemic. We identified global clade distribution eleven novel genetic variants that were almost absent rest world defined five subclades specific to UAE viral population. Cross-settlement human-to-human transmission was...
Overnutrition and genetics both contribute separately to pancreatic β-cell dysfunction, but how these factors interact is unclear. This study was aimed at determining whether microRNAs (miRNAs) provide a link between factors. In this study, miRNA-24 (miR-24) highly expressed in β-cells further upregulated islets from genetic fatty (db/db) or mice fed high-fat diet, subject oxidative stress. Overexpression of miR-24 inhibited insulin secretion proliferation, potentially involving 351...
Home blood pressure (BP) monitoring has been shown to be more effective than clinic BP for diagnosing and treating hypertension. However, reimbursement of home is uncommon in the United States because a lack evidence that it cost beneficial insurers. We develop decision-analytic model, which we use conduct cost–benefit analysis from perspective insurer. Model inputs are derived 2008 2011 claims data private health insurer States, 2009 2010 National Health Nutrition Examination Survey data,...
Few studies have investigated gender differences in dietary intake. The objective of this cross-sectional study was to examine patterns and their association with the prevalence metabolic syndrome. food intakes 3794 subjects enrolled by a two-stage cluster stratified sampling method were collected using valid semi-quantitative frequency questionnaire (FFQ). Metabolic syndrome (MetS) defined according International Diabetes Federation (IDF) its 35.70% sample (37.67% men 24.67% women). Dietary...
The emergence of the new coronavirus (nCoV-19) has impacted human health on a global scale, while interaction between virus and host is foundation disease. viral genome codes cluster proteins, each with unique function in event invasion or development. Under current adverse situation, we employ virtual screening tools searching for drugs natural products which have been already deposited DrugBank an attempt to accelerate drug discovery process. This study provides initial evaluation...
The leaves of Rhamnus erythroxylon Pall. are widely used as tea substitutes in northwest China for their fragrant aroma, anti-irritability, and digestion-enhancing properties. Ombuin, a main flavonoid compound found the leaves, exhibited notable anti-inflammatory antioxidant effects. However, its potential role treating neuroinflammatory-related diseases remains unexplored. Thus, this study aims to evaluate anti-neuroinflammatory effects ombuin explore underlying molecular mechanisms....
Objectives To assess the relationships between risk factors and incidence of nonfatal occupational injury coal mine workers Shanxi Province. Methods A cross-sectional study was conducted from July 2013 to December 2013, 4319 were recruited more than 200,000 employees who are exposed continuous potential injuries by using a two-stage stratified cluster sampling method. Trained interviewers having necessary medical knowledge face-to-face interviews with participants. Univariate multivariable...
ABSTRACT The annual increase of microwave exposure in human environments continues to fuel debates regarding its potential health impacts. This study monitored the EEG and ECG responses three Cynomolgus monkeys before at 0, 3, 7, 14, 30 days after 50 mW/cm² radiation for 15 min. findings revealed no significant differences power spectral densities (PSDs) whole brain, frontal, temporal lobes across various frequency bands (δ, θ, α, β, low‐γ, high‐γ) immediately up postexposure. Notable...
To unravel the source of SARS-CoV-2 introduction and pattern its spreading evolution in United Arab Emirates, we conducted meta-transcriptome sequencing 1067 nasopharyngeal swab samples collected between May 9th Jun 29th, 2020 during first peak local COVID-19 epidemic. We identified global clade distribution eleven novel genetic variants that were almost absent rest world defined five subclades specific to UAE viral population. Cross-settlement human-to-human transmission was related...
Inactivated coronavirus disease 2019 (COVID-19) vaccines such as CoronaVac and BBIBP-CorV have been widely used in China. However, more investigation is still needed to understand antibodies' duration effectiveness against severe acute respiratory syndrome 2 (SARS-CoV-2) variants the real world. In this study, 575 participants who had vaccinated with two or three doses of inactivated vaccine were recruited. Serum samples collected tested for anti-spike IgG neutralizing antibodies SARS-CoV-2...
Several prediction models for fatty liver disease (FLD) are available with limited externally validation and less comprehensive evaluation. The aim was to perform external direct comparison of 4 (the Fatty Liver Index, the Hepatic Steatosis ZJU index, Framingham Index) FLD both in overall population obese subpopulation. This cross-sectional study included 4247 subjects aged 20 65 years recruited from north Shanxi Province China. Anthropometric biochemical features were collected using...
Epidermal growth factor receptor (
Norovirus (NoV) infection is a major cause of gastroenteritis worldwide. The virus poses great challenges in developing vaccines with broad immune protection due to its genetic and antigenic diversity. To date, there are no approved NoV for clinical use. Here, we aimed develop broad-acting quadrivalent vaccine based on chimpanzee adenovirus vector, AdC68, carrying the capsid protein (VP1) noroviral GI GII genotypes. Compared intramuscular (i.m.), intranasal (i.n.), or other prime-boost...
Abstract Hypoxia complicates islet isolation for transplantation and may contribute to pancreatic β -cell failure in type 2 diabetes. Pancreatic -cells are susceptible hypoxia-induced apoptosis. Severe hypoxic conditions during the immediate post-transplantation period a main non-immune factor leading death graft failure. In this study, we identified transcription Ets-1 (v-ets erythroblastosis virus E26 oncogene homolog 1) as an early response gene against apoptosis -cells. regulates at...
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a widely secreted protein that regulates cell motility, proliferation, and apoptosis. Although it recognized TIMP-1-tetraspanin CD63 epithelial apoptosis how TIMP-1 controls motility not well understood. In this study, we identify tetraspanin CD82 (also called KAI1) as component the promiscuous interacting complex on surface human pancreatic adenocarcinoma cells. directly binds to N-terminal region through its large extracellular loop...
Although coal miners are susceptible to dyslipidaemia owing their highly risky and stressful working environment as well unhealthy lifestyle, very few studies have focused on this issue thus far. Therefore, study investigated the current epidemiological characteristics of among Chinese miners.Demographic, anthropometric, biochemical data were gathered from 4341 in China. Dyslipidaemia was diagnosed based serum lipid levels. Univariate multivariate logistic regression analyses used assess...
Electroacupuncture (EA) has been widely applied for illness prevention, treatment or rehabilitation in the clinic, especially pain management. However, molecular events that induce these changes remain largely uncharacterized. The periaqueductal gray (PAG) and spinal dorsal horn (DH) have verified as two critical regions response to EA stimulation analgesia. In this study, a genetic screen was conducted delineate gene expression profile PAG-DH of rats explore analgesic effect induced by...