A5089886905- Alzheimer's disease research and treatments
- Dementia and Cognitive Impairment Research
- Lung Cancer Treatments and Mutations
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Cytokine Signaling Pathways and Interactions
- Aging, Elder Care, and Social Issues
- Amyotrophic Lateral Sclerosis Research
- Cancer-related molecular mechanisms research
- Genomics and Chromatin Dynamics
- Circular RNAs in diseases
- RNA modifications and cancer
- DNA Repair Mechanisms
- RNA Research and Splicing
- Cancer Genomics and Diagnostics
- Multiple Sclerosis Research Studies
Hebei Medical University
2017-2023
Second Hospital of Hebei Medical University
2017-2023
Henan Agricultural University
2015-2016
Luoyang Central Hospital Affiliated to Zhengzhou University
2014
China has a large population of older people, but not yet undertaken comprehensive study on the prevalence, risk factors, and management both dementia mild cognitive impairment (MCI).For this national cross-sectional study, 46 011 adults aged 60 years or were recruited between March 10, 2015, Dec 26, 2018, using multistage, stratified, cluster-sampling method, which considered geographical region, degree urbanisation, economic development status, sex age distribution. 96 sites randomly...
We examined mRNA expression levels of ERCC1, BRCA1, RRM1, and human β-tubulin-III (TUBB3) in non-small-cell lung carcinoma (NSCLC) patients investigated the association between these genes clinical outcome NSCLC treatment.A total 366 who underwent surgery for were included this study.All received third-generation platinum-based chemotherapy as first-line treatment.The relative cDNA quantification TUBB3 was determined using a fluorescence-based, real-time detection method.We found that low...
1. This study was conducted to explore the promoter region of chicken ASB15 gene by detecting activities dual luciferase reporter and assess expression profiles in 10 different tissues from Gushi chickens. 2. Five vectors were constructed transfected into DF1 cells. The recombined plasmids measured core confirmed bioinformatic analysis. Total RNA extracted relative examined. 3. Data analysis indicated that located -955 -212 bp. Results showed expressed heart, breast muscle leg muscle. 4. has...
Single nucleotide polymorphism in microRNAs (miRNA) may influence their target gene selection and regulation efficiency, leading to animal phenotypic variation.The aim of this study was evaluate the possible effect single polymorphisms miRNA-1757 precursor region (pre-mir-1757) on economicrelated traits chicken.Genotyping performed using Sequenom MassArray ® iPLEX GOLD System.Association analysis SPSS19.0.The data showed that G/C significantly correlated with semi-evisceration weight,...
The present study aims to examine the relationship between polymorphisms in third intron of IFN-γ gene and their influence on susceptibility multiple sclerosis. A population-based case-control was used for this purpose. Multiple sclerosis patients healthy controls were interviewed. Genetic III at +2118 A/G +3586 G/ACT sites detected using polymerase chain reaction-restriction fragment length polymorphism. Genotypes allele frequencies position significantly different (P ≥ 0.05). However, no...