A5066589468- Nutrition and Health in Aging
- Cardiovascular Health and Risk Factors
- Health disparities and outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutritional Studies and Diet
- Dementia and Cognitive Impairment Research
- Health, Environment, Cognitive Aging
- Frailty in Older Adults
- Optical Coherence Tomography Applications
- Blood Pressure and Hypertension Studies
- Photoacoustic and Ultrasonic Imaging
- Sleep and related disorders
- Birth, Development, and Health
- Nutrition, Genetics, and Disease
- Health and Wellbeing Research
- Health and Well-being Studies
- Global Health Care Issues
- COVID-19 Clinical Research Studies
- Smoking Behavior and Cessation
- COVID-19 epidemiological studies
- Neurological Disease Mechanisms and Treatments
- Iron Metabolism and Disorders
- Advanced Fluorescence Microscopy Techniques
- Optical Imaging and Spectroscopy Techniques
- Erythropoietin and Anemia Treatment
Chinese People's Liberation Army
2015-2025
Chengdu University of Traditional Chinese Medicine
2025
Tongren University
2024
Chinese PLA General Hospital
2015-2024
Donghua University
2024
Wuhan Children's Hospital
2024
Huazhong University of Science and Technology
2024
Daqing Oilfield General Hospital
2018-2024
Hebei Medical University
2024
Zunyi Medical University
2024
China has a large population of older people, but not yet undertaken comprehensive study on the prevalence, risk factors, and management both dementia mild cognitive impairment (MCI).For this national cross-sectional study, 46 011 adults aged 60 years or were recruited between March 10, 2015, Dec 26, 2018, using multistage, stratified, cluster-sampling method, which considered geographical region, degree urbanisation, economic development status, sex age distribution. 96 sites randomly...
The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain.We collected data from 3098 patients with AD 81 representative centers across estimated for individual patient total 2015. Based this data, we re-estimated the worldwide AD.The annual cost per was US $19,144.36, were $167.74 billion are predicted to reach $507.49 2030 $1.89 trillion 2050. our results, estimates dementia $957.56 2015, will be $2.54 2030, $9.12 2050, much more...
Coronavirus Disease 2019 (COVID-19) is currently a global public health threat. Outside of China, Italy one the countries suffering most with COVID-19 epidemic. It important to predict epidemic trend in help develop strategies.
Abstract Objective To identify an optimal lifestyle profile to protect against memory loss in older individuals. Design Population based, prospective cohort study. Setting Participants from areas representative of the north, south, and west China. Individuals aged 60 years or who had normal cognition underwent apolipoprotein E (APOE) genotyping at baseline 2009. Main outcome measures were followed up until death, discontinuation, 26 December 2019. Six healthy factors assessed: a diet...
Biomarker changes that occur in the period between normal cognition and diagnosis of sporadic Alzheimer's disease have not been extensively investigated longitudinal studies.
Most existing studies focus on either the relationship between sarcopenia and depressive symptoms or cognitive functions. Few have examined functions simultaneously. This study aimed to analyze both in elderly by introducing activities of daily living explore mediating role mental health. used data from 2015 2018 China Health Retirement Longitudinal Study, including a total 3,552 older adults aged 60 above. We conducted descriptive statistical analysis correlation seemingly unrelated...
Objective The information on the changes of prevalence MetS in China is limited. Our objective was to assess a 10-year's change Chinese elderly population between 2001 and 2010. Methods We conducted two cross-sectional surveys representative sample aged 60 95 years Beijing 2010 respectively. defined according 2009 harmonizing definition. Results A total 2,334 participants (943 male, 1,391 female) 2,102 (848 1,254 completed survey. 50.4% (95%CI: 48.4%–52.4%) 58.1% 56.0%–60.2%) absolute 7.7%...
As the most important risk factors of cardiovascular disease, pre-hypertension and hypertension are public health challenges. Few studies have focused on trends specifically for aging population in China. Given anticipated growth elderly China, there is an urgent need to document conditions this population.We conducted two cross-sectional surveys Chinese adults aged ≥60 years 2001 2010. A total 2,272 (943 males, 1,329 females) 2,074 (839 1,235 participants were included surveys,...
Objective. This study aimed to evaluate the association between serum uric acid (SUA) levels within a normal high range and risk of metabolic syndrome (MetS) among community elderly explore sex difference. Design Methods. A cross-sectional was conducted in representative urban area Beijing 2009 2010. two-stage stratified clustering sampling method used 2102 participants were included. Results. The prevalence hyperuricemia MetS 16.7% 59.1%, respectively. There strong four components women...
This study aimed to determine whether there is a difference in the risk of death/critical illness between different stages hepatitis B virus (HBV) (resolved B, HBeAg (-) chronic [CHB]/infection, (+) CHB/infection, and HBV reactivation) coinfected with coronavirus disease 2019 (COVID-19); if difference, it due abnormal liver function what extent.This cohort included all COVID-19 inpatients single-center tertiary care academic hospital Wuhan, Hubei, China, February 4, 2020, follow-up April 14,...
To examine associations between metabolic syndrome (MetS) and its individual components with risk of mild cognitive impairment (MCI) among community elderly explore the age difference.Cross-sectional study.About 2,102 aged 60 older residents in Beijing metropolitan area, China.Cognitive function was assessed by Mini-Mental State Examination (MMSE). MetS defined 2009 harmonizing definition. Overnight-fasting blood samples were obtained to measure biochemistry indicators.The prevalence MCI...
A thorough understanding of the spatiotemporal dynamics blood supply and tissue viability is great importance in stroke researches. In current study, vascular cellular responses to focal ischemia were monitored with optical coherence tomography on chronic rat photothrombotic model. The 3D mapping perfusion scattering achieved by analyzing temporal depth attenuation intrinsic backscattered light respectively. Optical revealed that vessels different types presented various spatial during...
The intricate interrelationship between oral health, the number of teeth, microbiota, and frailty remains largely unexplored in clinical research. This study aimed to investigate microbiome, frailty. Data from 4518 participants NHANES 2009-2012 were analyzed. Frailty was measured using 48-item Index (FI), microbiota diversity through 16S rRNA sequencing, tooth retention via examination. Multivariable logistic regression restricted cubic spline (RCS) evaluated associations alpha Mediation...
Objective: To explore the association between physical activity (PA) level and all-cause mortality in elderly with different obesity status Beijing. Methods: The study subjects were from Cardiovascular Cognitive Healthy Study Middle-Aged Elderly Residents of Beijing, a total 3 746 individuals aged ≥60 years baseline survey 2013 2015 included study. Questionnaire examination conducted to collect basic information individuals. metabolic equivalent was used calculate PA level, an international...
Objective: To study the association between subtypes of hypertension and risk for all-cause mortality cardio-cerebrovascular mortalities in elderly communities Beijing. Methods: The data were collected from Beijing Healthy Aging Cohort Study. 5 urban areas (former Xicheng, former Xuanwu, Fangshan, Haidian Tongzhou) 4 rural (Yanqing, Miyun, Huairou Daxing) selected as subjects by multi-stage stratified cluster random sampling. baseline survey was conducted July 2009 to September 2015....
Background: As evidence on depression and health-related quality of life (HRQoL) among the oldest-old is currently limited, this study aimed to re-examine association between HRQoL centenarians. Methods: We analyzed cross-sectional data from China Hainan Centenarian Cohort Study (CHCCS). The 15-item Geriatric Depression Scale (GDS-15) EuroQol five dimensions-visual analog scale (EQ-5D-VAS) were used evaluate HRQoL, respectively. Poor health states defined as EQ-5D index<0.665. Based their...
To determine if alcohol consumption is a risk factor for obstructive sleep apnea (OSA) and nocturnal oxygen desaturation.
No licensed medications are available to treat vascular dementia (VaD).Patients were randomly assigned experimental groups (SaiLuoTong [SLT] 360 or 240 mg for A and B 52 weeks, respectively) placebo group (SLT C only from weeks 27 52, respectively).Three hundred twenty-five patients included in final analysis. At week 26, the difference VaD Assessment Scale-cognitive subscale scores was 2.67 (95% confidence interval, 1.54 3.81) versus C, 2.48 (1.34 3.62) (both P < .0001). However, at no...
Objective To investigate the relationship between upper and lower limb muscle strength health-related quality of life (HRQoL) a Chinese rural, elderly population. Design A population-based, cross-sectional study. Setting Miyun, Beijing, China. Participants The participants this study were 2083 (834 men 1249 women) older adults from rural area, (average age ≥60 years), living in Miyun county, located on outskirts Beijing. Data collected May October 2014. Handgrip timed up go tests (TUGT)...
Abstract Background Coronavirus Disease 2019 (COVID-19) is currently a global public health threat. Outside of China, Italy one the most suffering countries with COVID-19 epidemic. It important to predict epidemics trend epidemic in help develop strategies. Methods We used time-series data from Jan 22,2020 Mar 16,2020. An infectious disease dynamic extended susceptible-infected-removed (eSIR) model, which covers effects different intervention measures dissimilar periods, was applied estimate...