A5101777814- Genetic Mapping and Diversity in Plants and Animals
- Rice Cultivation and Yield Improvement
- GABA and Rice Research
- HER2/EGFR in Cancer Research
- Breast Cancer Treatment Studies
- Advanced Breast Cancer Therapies
- Cancer-related Molecular Pathways
- Cancer Treatment and Pharmacology
- Environmental and Agricultural Sciences
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Genetics and Plant Breeding
- Cancer, Hypoxia, and Metabolism
- Viral Infections and Immunology Research
- Monoclonal and Polyclonal Antibodies Research
- Cardiac electrophysiology and arrhythmias
- Neurobiology and Insect Physiology Research
- Cancer Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Vaccine Coverage and Hesitancy
- Chronic Lymphocytic Leukemia Research
- Global Health Care Issues
- Inhalation and Respiratory Drug Delivery
- Crop Yield and Soil Fertility
- Pulmonary Hypertension Research and Treatments
Zhongshan Hospital of Xiamen University
2025
Fudan University
2025
Guangzhou University of Chinese Medicine
2025
Tianjin Medical University Cancer Institute and Hospital
2025
National Clinical Research
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2025
Institute of Plant Protection
2024-2025
Tianjin University of Traditional Chinese Medicine
2025
Dalian Ocean University
2025
Second Xiangya Hospital of Central South University
2023-2025
Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with favorable safety profile demonstrated in preclinical phase I studies. BRIGHT‐1 aimed to further explore the efficacy of bireociclib monotherapy patients locally advanced, recurrent or metastatic, hormone receptor‐positive human epidermal growth factor receptor 2‐negative (HR + /HER2 − ) breast cancer who had progressed on after prior chemotherapy endocrine therapy advanced...
To determine whether patients with congestive heart failure and true left bundle branch block (LBBB) morphology have better response to cardiac resynchronization therapy (CRT) than do without LBBB. We defined LBBB as conventional plus QRS duration ≥130 ms mid-QRS notching/slurring in at least two of the leads I, aVL, V1, V2, V5, or V6. prospectively enrolled 58 allocated them three groups: (t-LBBB, n = 22); non-true (nt-LBBB, no notch notches fewer leads, 17); non-specific intraventricular...
Aside from enterovirus 71 (EV71) and coxsackie virus A16 (CV-A16), viruses that are known to cause hand-foot-and-mouth disease (HFMD), epidemiological profiles of other enteroviruses induce HFMD limited. We collected 9949 laboratory surveillance cases 1230 serum samples infants children in Shanghai 2012-2016. Since 2013, CV-A6 has displaced EV71 CV-A16 become the predominant serotype. Interestingly, novel patterns infections were observed, with one large peak both 2012 2014, followed by two...
Patients with diabetes are more susceptible to severe acute respiratory syndrome-associated coronavirus (SARS-CoV)-2 infection, but vaccine hesitancy is a problem in this population. We investigated the prevalence of SARS-CoV-2 among patients China through cross-sectional survey from April and August 2021 using questionnaire administered at two hospitals affiliated Changzhi Medical College (Shanxi, China). The health belief model (HBM) used examining factors influencing hesitancy. After...
Abstract Background Smoking remains a major risk factor for the development and progression of chronic obstructive pulmonary disease (COPD). Due to adolescent smoking associated with worse health state, age, at which an individual started smoking, might play key role in shaping trajectory COPD severity. Methods We conducted observational study from September 2016 through January 2023 eligible patients hospitalized COPD. Patients who during alveolar stage (ADS, initiation ≤ 24 years old) were...
Single nucleotide polymorphism (SNP) is the most abundant molecular marker associated with many physiologic and pathologic phenotypes. An isothermal, accurate cost-effective SNP detection could make a great difference in point-of-care testing (POCT) or on-site diagnosis. However, there are two challenges, expensive instrument labor-intensive process, faced by development of detection. We reported novel typing method based on probe-enhanced loop-mediated isothermal amplification (PE-LAMP),...
Abstract Biological evidence suggests that vitamin D has numerous anticancer functions, but the associations between status and colorectal cancer (CRC) risk survival remain inconclusive. Based on UK Biobank, we prospectively evaluated of season‐standardized 25‐hydroxyvitamin (25(OH)D) concentrations with CRC among 360 061 participants, 2509 cases. We observed an inverse linear relationship 25(OH)D ( P for linearity = .01; HR per 1‐SD increment, 0.95; 95% CI, 0.91‐0.99). Compared to lowest...
Guidelines specify steroids as therapy for acute exacerbation of chronic obstructive pulmonary disease (AECOPD). However, the duration survival benefit associated with and optimal dosage nebulized budesonide (NB) during hospitalization remain unclear. We conducted a retrospective study hospitalized AECOPD patients. The primary endpoint was all-cause mortality after discharge. Cox regression analysis used to determine impact steroid on survival. Wilcoxon showed positive systemic...
Bacterial infection is frequently observed in disease outbreaks of aquatic animals, making it significance to isolate and identify the bacterial pathogens. In this study, diseased individuals Crassostrea gigas were sampled from nearshore area Zhanjiang, Guangdong May 2023. Culturable bacteria isolated tissue a pathogenic strain labeled as H27 was screened through hemolysis test challenge experiments. Morphological characterization, 16S rRNA gene sequence-based molecular identification...
This study aimed to analyze the characteristics of patients undergoing percutaneous liver biopsies and investigate pathological manifestations four major diseases across different age groups. A retrospective analysis was conducted 4,717 pathology reports from 2009 2024. The population comprised 4,188 who underwent biopsies, with 408 receiving two 50 three or more procedures. Most (4,171) were performed between 2013 2023. Disease categorization, temporal distribution, groups assessed employed...
Dry-hot wind during the grain filling period is a prevalent agrometeorological challenge worldwide, causing significant functional leaf senescence, disrupting process, and ultimately leading to wheat yield loss. Although studies have explored alleviating effects of EBR under abiotic stress, its application in potential mechanisms underlying role mitigating dry-hot still require further investigation. Using dry-hot-wind-sensitive cultivar Jinan 17 (JN17) dry-hot-wind-resistant Liangxing 77...
Early rehabilitation after stroke can improve the prognosis of patients and enhance effectiveness quality rehabilitation. Whether Quality Control Circle (QCC), as a management method, be used to early intervention rate has not been reported. This study aimed investigate QCC in increasing patients, providing reference program for improvement medicine. The was conducted based on repeated measurement design. applied at Zhongshan Hospital (Xiamen), Fudan University from August December 2023....
<title>Abstract</title> Background Nurses' leisure crafting can affect their mental health and job performance. This study aims to investigate the current situation of among nurses in cancer specialized hospitals through a cross - sectional survey method analyze its influencing factors. Method From July August 2024, convenience sampling was used select 530 clinical from tertiary hospital Tianjin. A general information survey, Leisure Crafting Scale, scale, nurse perceived organizational...
Background: "Treatable traits (TTs)" is a precision medicine strategy for the management of chronic airway diseases. However, data on TTs in hospitalized AECOPD patients are limited. This study aimed to determine prevalence Chinese with and which predict future exacerbation risk, develop an prediction model. Methods: multicenter, cohort recruited from January 2022 April 2023. Participants underwent multidimensional assessment characterize were then followed up one year. Cox regression...