A5035698166- Pneumonia and Respiratory Infections
- Bacterial Infections and Vaccines
- Respiratory viral infections research
- Immunodeficiency and Autoimmune Disorders
- Streptococcal Infections and Treatments
- Infective Endocarditis Diagnosis and Management
- Antibiotic Resistance in Bacteria
- Pneumocystis jirovecii pneumonia detection and treatment
- Biosensors and Analytical Detection
- Pediatric health and respiratory diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Microbial Inactivation Methods
- Microbial infections and disease research
- Influenza Virus Research Studies
- Essential Oils and Antimicrobial Activity
- Otolaryngology and Infectious Diseases
- Antimicrobial Resistance in Staphylococcus
- Salmonella and Campylobacter epidemiology
- Reproductive tract infections research
- Listeria monocytogenes in Food Safety
- Bacterial Identification and Susceptibility Testing
- Indoor Air Quality and Microbial Exposure
Narodowy Instytut Leków
2014-2025
University of Warsaw
2016
Three pathogens,<italic>N. meningitidis</italic>,<italic>H. influenzae</italic>, and<italic>S. pneumoniae</italic>, have been successfully detected and identified in clinical cerebrospinal fluids using SERS method.
The epidemiology of invasive listeriosis in humans appears to be weakly characterized Poland, the sixth most populous member state European Union. We obtained antimicrobial susceptibility data, PCR-serogroups and genotypic profiles for 344 isolates Listeria monocytogenes, collected between 1997 2013 Poland. All were susceptible 10 tested antimicrobials, except one that was resistant tetracycline minocycline harbored tet(M), tet(A) tet(C) genes. Overall, no increasing MIC values observed...
Background Neisseria meningitidis is a leading etiologic agent of severe invasive disease. The objective the study was to characterise meningococcal disease (IMD) epidemiology in Poland during last decade, based on laboratory confirmed cases. Methods encompassed all meningococci collected between 2002 and 2011 National Reference Centre for Bacterial Meningitis. isolates were re-identified characterised by susceptibility testing, MLST analysis, porA fetA sequencing. A PCR technique used...
We investigated pneumococcal carriage among unvaccinated children under five years of age at a time when the conjugate polysaccharide vaccine (PCV) was introduced in Poland into national immunization program (NIP). Paired nasopharyngeal swab (NPS) and saliva samples collected between 2016 2020 from n = 394 were tested with conventional culture using qPCR. The rate detected by 25.4% (97 394), qPCR 39.1% (155 40.1% (158 394) overall. risk significantly elevated day care center attendees,...
The introduction of pneumococcal conjugate vaccines (PCV) into the national immunization programs (NIPs) has significantly reduced number infections. However, infections caused by isolates non-vaccine serotypes (NVT) started spreading shortly thereafter and strains NVT 19A have become main cause invasive disease burden worldwide. aim study was to characterize serotype pneumococci GPSC1/CC320 circulating in Poland before PCV Polish NIP 2017 compare them from other countries where PCVs were...
Streptococcus pyogenes (group A Streptococcus, GAS) is a major human pathogen and causes every year over 600 millions upper respiratory tract onfections worldwide. Untreated or repeated infections may lead to post-infectional sequelae such as rheumatic heart disease, cause of GAS-mediated mortality. There no comprehensive, longitudinal analysis the M type distribution strains isolated in Poland. Single reports describe rather their antibiotic resistance patterns focus on invasive isolates....
Neisseria meningitidis serogroup B (MenB) has recently become the major cause of invasive meningococcal disease in Poland. Therefore, purpose this study was to characterize MenB isolates, responsible for 2010–2016, by MLST and sequencing genes encoding proteins used as 4CMenB vaccine antigens. Two methods coverage estimation were performed: extrapolation MATS results Polish meningococci 2010–2011 (exMATS) gMATS, which combines genotyping results. Among 662 isolates 20 clonal complexes (CC)...
This study evaluated the usefulness of Pneumotest-Latex assay for serotyping Streptococcus pneumoniae isolates directly in clinical samples. With an agreement 88.1% with a PCR-based reference method, this test can be useful tool purpose, especially laboratories that do not have access to nucleic acid amplification technologies.
The aim of this study was to describe the characteristics invasive meningococcal disease (IMD) among patients under 20 years age in Poland from 2009 2011, based on data collected by National Reference Centre for Bacterial Meningitis (NRCBM). performed all Neisseria meningitidis Poland, between and 2011 NRCBM. isolates were identified serotyped. MICs determined Etests or M.I.C.Evaluators. A PCR technique used identification etiological agent directly clinical materials case a negative...
Abstract We investigated pneumococcal carriage among unvaccinated children under five years of age at the time conjugate polysaccharide vaccine (PCV) introduction into national immunization program (NIP). Paired nasopharyngeal swab (NPS) and saliva samples collected between 2016 2020 from n=394 were tested with conventional culture using qPCR. The rate detected by was 25.4% (97 394), qPCR 39.1% (155 40.1% (158 394) overall. risk significantly elevated day care center attendees, during...