A5088115198- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- RNA Research and Splicing
- Extracellular vesicles in disease
- Circular RNAs in diseases
- Biosensors and Analytical Detection
- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Cancer Cells and Metastasis
- RNA and protein synthesis mechanisms
- RNA regulation and disease
- Endoplasmic Reticulum Stress and Disease
- Hepatitis B Virus Studies
- Cell Adhesion Molecules Research
- SARS-CoV-2 detection and testing
- Epigenetics and DNA Methylation
- Toxin Mechanisms and Immunotoxins
- Ion channel regulation and function
- Phagocytosis and Immune Regulation
- Galectins and Cancer Biology
- Caveolin-1 and cellular processes
- Genetic factors in colorectal cancer
- SARS-CoV-2 and COVID-19 Research
- Cancer Immunotherapy and Biomarkers
National Research University Higher School of Economics
2019-2025
Institute of Bioorganic Chemistry
2024-2025
Engelhardt Institute of Molecular Biology
2005-2020
P.A. Hertzen Moscow Oncology Research Institute
2016-2020
Ministry of Health of the Russian Federation
2016-2019
Medical Radiological Research Center
2019
Oncological Dispensary No. 2
2019
BioClinicum (Russia)
2017
Russian Academy of Sciences
2010
The purpose of this study was to investigate the prognostic significance cholesterol uptake genes in predicting survival breast cancer patients. Cholesterol plays a crucial role homeostasis tumor cells. It is known that levels can influence important parameters disease, such as sensitivity therapy, progression, and metastasis cancer. Previous studies suggest subtypes exhibit differences metabolism. objectives were determine whether have for overall patients, evaluate if varies between...
Abstract MicroRNAs (miRNAs) are a family of short noncoding RNAs that posttranscriptionally regulate gene expression and play an important role in multiple cellular processes. A significant percentage miRNAs intragenic, which is often functionally related to their host genes playing either antagonistic or synergistic roles. In this study, we constructed analyzed the entire network intergenic interactions induced by intragenic miRNAs. We further focused on core network, was defined as union...
α-Latrotoxin (α-LTX) was found to form two-dimensional (2D) monolayer arrays in solution at relatively low concentrations (0.1 mg/mL), with the toxin tetramer constituting a unit cell. The crystals were imaged using cryogenic electron microscopy (cryoEM), and image analysis yielded ~12 Å projection map. At this resolution, no major conformational changes between crystalline states of α-LTX tetramers observed. Electrophysiological studies showed that, under conditions crystallization,...