A.F. Pierre

ORCID: 0000-0003-4501-5428
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About
Contact & Profiles
Research Areas
  • Transplantation: Methods and Outcomes
  • Organ Transplantation Techniques and Outcomes
  • Cancer Genomics and Diagnostics
  • Lung Cancer Treatments and Mutations
  • Renal Transplantation Outcomes and Treatments
  • Educational Tools and Methods
  • Polyomavirus and related diseases
  • Acoustic Wave Phenomena Research
  • Functional Brain Connectivity Studies
  • Cancer-related molecular mechanisms research
  • Educational and Social Studies
  • Pleural and Pulmonary Diseases
  • Advanced Adaptive Filtering Techniques
  • RNA Interference and Gene Delivery
  • Cell Image Analysis Techniques
  • Mechanical Circulatory Support Devices
  • Vehicle Noise and Vibration Control
  • Pulmonary Hypertension Research and Treatments
  • Virus-based gene therapy research
  • Lung Cancer Diagnosis and Treatment
  • Eosinophilic Disorders and Syndromes
  • Cardiac Structural Anomalies and Repair
  • Xenotransplantation and immune response
  • Hepatocellular Carcinoma Treatment and Prognosis
  • CRISPR and Genetic Engineering

Allen Institute for Brain Science
2023-2024

Brown University
2023-2024

University Health Network
2003-2023

Health Net
2023

University of Toronto
1998-2016

Toronto Public Health
2016

Toronto General Hospital
2001-2011

Princess Margaret Cancer Centre
2005

We describe a novel technique of pumpless extracorporeal life support in four patients with cardiogenic shock due to end-stage pulmonary hypertension (PH) including veno-occlusive disease (PVOD) using lung assist device (LAD). The was connected via the arterial main trunk and left atrium, thereby creating septostomy-like shunt unique addition gas exchange abilities parallel lung. Using this approach, all were successfully bridged bilateral transplantation combined heart-lung transplantation,...

10.1111/j.1600-6143.2009.02549.x article EN cc-by-nc-nd American Journal of Transplantation 2009-03-06

Donor-specific HLA antibodies (DSA) have an adverse effect on short-term and long-term lung transplant outcomes. We implemented a perioperative strategy to treat DSA-positive recipients, leading equivalent rejection graft survival Pretransplant DSA were identified HLA-A, B, C, DR DQ antigens. patients transplanted if panel reactive antibody (PRA) ≥30% or medically urgent desensitized with plasma exchange, intravenous immune globulin, antithymocyte globulin (ATG), mycophenolic acid (MPA)....

10.1111/ajt.13076 article EN cc-by-nc-nd American Journal of Transplantation 2015-01-23

Lymphomatoid granulomatosis is a rare lymphoproliferative disorder which affects extranodal sites, most commonly lung. Radiologically, it typically presents with multiple nodular opacities that may wax and wane. The reversed halo sign has previously been reported in cryptogenic organizing pneumonia more recently South American blastomycosis. We describe case of histologically proven lymphomatoid patient who presented initially the typical opacities, subsequently progressed into sign. To best...

10.1259/bjr/46361210 article EN British Journal of Radiology 2007-08-01

Neuroscience research has evolved to generate increasingly large and complex experimental data sets, advanced science tools are taking on central roles in neuroscience research. Neurodata Without Borders (NWB), a standard language for neurophysiology data, recently emerged as powerful solution management, analysis, sharing. We here discuss our labs’ efforts implement NWB pipelines. describe general principles specific use cases that illustrate successes, challenges, non-trivial decisions...

10.1523/jneurosci.0381-24.2024 article EN Journal of Neuroscience 2024-09-18

Neuroscience research has evolved to generate increasingly large and complex experimental data sets, advanced science tools are taking on central roles in neuroscience research. Neurodata Without Borders (NWB), a standard language for neurophysiology data, recently emerged as powerful solution management, analysis, sharing. We here discuss our efforts implement NWB pipelines. describe general principles specific use cases that illustrate successes, challenges, non-trivial decisions software...

10.48550/arxiv.2310.04317 preprint EN cc-by-nc-sa arXiv (Cornell University) 2023-01-01

7217 Background Lung cancer remains a leading cause of cancer-related mortality in North America. Despite potentially curative resection, NSCLC patients remain at high risk relapse and death, with five-year survival less than 60%. Several randomized trials now confirm the benefit adjuvant platinum-based chemotherapy seen Collaborative Group meta-analysis, including IALT, NCIC BR 10 CALGB 9633, absolute improvements 4 & 5-year to15%. This study examines whether referral patterns for therapy...

10.1200/jco.2005.23.16_suppl.7217 article EN Journal of Clinical Oncology 2005-06-01
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