A5057081242- Colorectal Cancer Screening and Detection
- Breast Implant and Reconstruction
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Cancer Genomics and Diagnostics
- Sarcoma Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Nutrition, Genetics, and Disease
- Bacterial Identification and Susceptibility Testing
- Pancreatitis Pathology and Treatment
- Reconstructive Facial Surgery Techniques
- Soft tissue tumor case studies
- Breast Cancer Treatment Studies
- Soft tissue tumors and treatment
- Intestinal Malrotation and Obstruction Disorders
- Breast Lesions and Carcinomas
- Body Image and Dysmorphia Studies
- Diverticular Disease and Complications
- Body Contouring and Surgery
- Infective Endocarditis Diagnosis and Management
- Vascular Tumors and Angiosarcomas
- Metastasis and carcinoma case studies
- Appendicitis Diagnosis and Management
- Cancer, Lipids, and Metabolism
Copenhagen University Hospital
2017-2023
Rigshospitalet
2021-2023
University of Copenhagen
2013-2022
Smerteklinikken
2021-2022
Hvidovre Hospital
2013-2020
The prognosis of patients with atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) remains uncertain no standardized follow-up programs have been established.To recommend a program AFX PDS based on nationwide long-term estimates local recurrence metastasis.All in Denmark between 2002 2022 were included. Danish National Registries used to estimate the risks metastasis for PDS.The 5-year risk was 10% 17% PDS. 0.8% 16% metastasized within 3 years >90% lungs as primary site (50%)....
Serological biomarkers may be an option for early detection of colorectal cancer (CRC). The present study assessed eight cancer-associated protein in plasma from subjects undergoing first time ever colonoscopy due to symptoms attributable neoplasia. Plasma AFP, CA19-9, CEA, hs-CRP, CyFra21-1, Ferritin, Galectin-3 and TIMP-1 were determined EDTA-plasma using the Abbott ARCHITECT® automated immunoassay platform. Primary endpoints (i) CRC high-risk adenoma (ii) CRC. Logistic regression was...
The aim was to evaluate serum levels of circulating cell-free nucleosomes (ccfn) containing a variety epigenetic signals including 5-methylcytosine DNA, histone modifications H3K9Me3, H3K9Ac, H3S10PO4, H3K36Me3, H4K20Me3, H4PanAc and pH2AX, nucleosome variant H2AZ adducts with HMGB1 EZH2 as well ccfn per se, in addition develop predictor models based on the above mentioned carcinoembryonic antigen (CEA), early detection colorectal cancer (CRC). Blood-samples were collected from 4,105...
Programs for population screening of colorectal cancer (CRC) have been implemented in several countries with fecal immunochemical testing (FIT) as the preferred platform. However, major obstacle a feces-based method is limited compliance that reduces clinical sensitivity detection participants non-symptomatic CRC. Therefore, research approaches initiated to develop concepts based on biomarkers blood. Preliminary results show protein, genetic, epigenetic, and metabolomic components may be...
Anatomical implants provide a wide range of options in terms implant dimensions for breast augmentation. Nevertheless, many surgeons choose not to use anatomical due the risk rotation malposition and because their advantages over round are clearly defined.A retrospective review medical records was performed on all women who underwent augmentation or exchange with microtextured from 2012 2019 single private clinic. The authors focused outcomes subgroup glandular ptosis nipple placement below...
Aim: To evaluate pre-analytical variables of circulating cell-free nucleosomes containing 5-methylcytosine DNA (5mC) or histone modification H3K9Me3 (H3K9Me3).Materials and methods: Six studies were designed to assess the possible influence variables. Study 1: stasis contamination with white-cells platelets. 2: within-day variations. 3: day-to-day variation. 4: temperature during handling storage, neoplastic disease. 5: colonoscopy. 6: surgical trauma. 5mC measurements performed using...
Introduction: Plasma levels of eight combined proteins have shown value as biomarkers for detection colorectal cancer (CRC). However, their in identifying adenoma needs further evaluation. The aim was to evaluate the (AFP, CA19-9, CEA, CyFra21-1, Ferritin, Galectin-3, hs-CRP and TIMP-1) high-risk (HRA) prediction recurrence adenoma. Furthermore, discrimination between HRA low-risk (LRA) or CRC lesions evaluated. Methods: study included 4698 individuals undergoing diagnostic colonoscopy....
Blood-based protein biomarkers for detection of colorectal cancer (CRC) have been submitted to intense research improve the full potential in screening CRC.The aim was explore diagnostic performance 92 proteins related inflammation and carcinogenesis CRC or precancerous lesions.Blood-samples were collected from 4,698 individuals undergoing colonoscopy. An explorative unmatched case-control study designed with 294 cases (individuals high-risk adenoma) 490 controls low-risk adenoma,...
When repetitive infective endocarditis episodes occur in the same patient, accurate species identification is essential for differentiating relapse and a new episode. We report case, which has had four of IE within 2 years: episode 1 due to Enterococcus faecalis, Mitis group Streptococcus, Episodes 3 4 Salivarius Streptococcus. Detailed molecular examinations using Multi Locus Sequence Analysis (MLSA) convincingly documented that two strains from were different. Thus, it was not relapse, but...
Background At present plasma tissue inhibitor of metalloproteinases-1 (TIMP-1) is undergoing validation as a biological marker in colorectal cancer (CRC). The clinical implementation TIMP-1 prognosis, prediction, screening and monitoring CRC requires robust information to the influence preanalytical factors, including inter- intrapersonal variations. aim study was evaluate possible effects smoking on level from healthy subjects. Materials Methods Forty-six never-smokers 48 daily smokers...