A5101560696- Cancer-related molecular mechanisms research
- Viral-associated cancers and disorders
- Medical Imaging Techniques and Applications
- RNA modifications and cancer
- Circular RNAs in diseases
- MicroRNA in disease regulation
- S100 Proteins and Annexins
- Radiomics and Machine Learning in Medical Imaging
- Medical Image Segmentation Techniques
- Advanced X-ray and CT Imaging
- Monoclonal and Polyclonal Antibodies Research
- Industrial Vision Systems and Defect Detection
- Cancer-related gene regulation
- HER2/EGFR in Cancer Research
- Surface Roughness and Optical Measurements
- RNA Research and Splicing
- Gastric Cancer Management and Outcomes
- Advanced Glycation End Products research
- Cell death mechanisms and regulation
- Lung Cancer Diagnosis and Treatment
- Wnt/β-catenin signaling in development and cancer
- Bone and Dental Protein Studies
- Dental Research and COVID-19
- Helicobacter pylori-related gastroenterology studies
- Optical Imaging and Spectroscopy Techniques
Chung Yuan Christian University
1996-2025
National Taiwan University Hospital
2025
Guangdong Pharmaceutical University
2024
Qufu Normal University
2024
Fujian Provincial Cancer Hospital
2011-2023
Fujian Medical University
2011-2023
Chengdu University of Traditional Chinese Medicine
2022
Wenzhou Medical University
2015
The University of Texas Southwestern Medical Center
2015
Yale University
2011
Controlling healthcare-associated infections (HAIs) remains one of the major challenges faced by healthcare systems worldwide. Effective management HAIs has become a critical indicator for evaluating quality services provided medical institutions. This study aims to compare outcomes environmental and instrument cleaning audits using an adenosine triphosphate (ATP) bioluminescence assay prevent spread micro-organisms within environments. The ATP monitoring system employs cold light integrated...
Abstract Epstein‐Barr virus (EBV) Bam HI A rightward transcripts (BART) encoded microRNAs (EBV‐miR‐BARTs) are abnormally highly expressed in nasopharyngeal carcinoma (NPC). This study aims to investigate the diagnostic and prognostic performance of miR‐BART7‐3p miR‐BART13‐3p. Plasma levels EBV DNA, miR‐BART7‐3p, miR‐BART13‐3p were examined by quantitative PCR 483 treatment‐naïve NPC patients 243 controls without NPC. The was comparing plasma with rates distant metastasis during follow‐up....
The use of positron emission tomography (PET) in quantitative fluorodeoxyglucose (FDG) studies aging and dementia has been limited by partial volume effects. A general method for correction effects (PVE) PET involves the following common procedures: segmentation MRI brain images into gray matter (GM), white (WM), cerebral spinal fluid (CSF), muscle (MS) components: registration; generation simulated images. Afterward, two different approaches can be taken. first approach derives a...
Nasopharyngeal carcinoma is an Epstein-Barr virus (EBV)-associated tumor that highly common in southern China. Our previous sequencing data demonstrated the EBV-encoded microRNA BART8-3p was most upregulated nasopharyngeal (NPC) and closely associated with metastasis of NPC. However, values plasma NPC patients have not yet been well characterized.We quantified expression by quantitative real-time PCR 205 newly diagnosed patients. Kaplan-Meier analysis used to compare overall survival (OS),...
We evaluated shedding of epidermal growth factor type II receptor (Her2/neu) extracellular domain (ECD) in primary uterine serous carcinoma (USC) cell lines and the serum USC patients its biological effects experiments trastuzumab-induced cytotoxicity vitro. Her2/neu expression was by immunohistochemistry (IHC), real-time PCR flow cytometry, while c-erbB2 gene amplification assessed using fluorescent situ hybridisation (FISH). ECD levels supernatants 38 19 controls were tested ELISA. The...
Annexin A2 (ANXA2) has been found to be involved in cancer proliferation, metastasis and prognosis; however, its exact role nasopharyngeal carcinoma (NPC) radioresistance remains unknown. We that ANXA2 expression was correlated with prognosis NPC patients, longer overall survival patients low than those high expression. knockdown increased the radiosensitivity radioresistant cells, overexpression decreased cells. Knocking-down irradiation-induced apoptosis of induced G2/M phase arrest cells...
Circular RNA (CircRNA) is related to tumor development. Nevertheless, the regulation and function of hsa_circ_0006692 its interactions with miR-205-5p CDK19 in development non-small-cell lung cancer (NSCLC) were un-explored. The correlations expression levels NSCLC specimens cells pathological characteristics studied. assessed real-time PCR, RNA-binding protein immunoprecipitation (RIP), luciferase reporter, pull-down, fluorescence situ hybridization (FISH). roles on cell growth, invasion,...
SNHG8, a family member of small nucleolar RNA host genes (SNHG), has been reported to act as an oncogene in gastric carcinoma (GC). However, its biological function Epstein–Barr virus (EBV)-associated cancer (EBVaGC) remains unclear. This study investigated the role SNHG8 EBVaGC. Sixty-one cases EBVaGC, 20 non-EBV-infected (EBVnGC), and relative cell lines were studied for expression BHRF1 (BCL2 homolog reading frame 1) encoded by EBV with Western blot qRT-PCR assays. The relationship...
A pair of positively charged stable isotope labeling (SIL) agents, (4-carbonochloridoylphenyl)-trimethylazanium iodide (d0-CCPTA) and d6-CCPTA, were designed synthesized. These agents employed in the precolumn advanced glycation end products (AGEs) within 5 min under mild conditions. Through derivatization, mass spectrometry response AGEs was enhanced by approximately 2 orders magnitude. The detection quantitation limits ranges 3.1–7.1 10.0–23.7 ng/kg, respectively. recoveries range...
This review primarily focuses on the latest developments in Lewis acid-catalyzed strain-release cycloaddition reactions of BCBs.
A hybrid attenuation correction technique (ACT) is under development for /sup 18/F-FDG total body positron emission tomography (PET). With a short transmission scan of the thorax, any time within few days imaging session, this can correct in entire body. Segmentation, registration, and active contour finding techniques are applied to both images locate map major attenuating structures This eliminates need patient remain still from start end without added noise simultaneous or post...
Non-coding RNAs have been shown to play important regulatory roles, notably in cancer development. In this study, we investigated the role of microRNAs and circular Nasopharyngeal Carcinoma (NPC) by constructing a circRNA-miRNA-mRNA co-expression network performing differential expression analysis on mRNAs, miRNAs, circRNAs. Specifically, Epstein-Barr virus (EBV) infection has found be an risk factor for NPC, potential pathological differences may exist EBV+ EBV- subtypes NPC. By comparing...
Nasopharyngeal carcinoma (NPC) is rare worldwide but remains highly prevalent in endemic regions, notably southern China. Radiotherapy the treatment of choice for NPC, radioresistance has been identified as a major cause therapeutic failure. The Wnt/β-catenin signaling found to be involved NPC radioresistance; however, effect β-catenin overexpression on unknown until now. This study aimed examine impact radiosensitivity human CNE-2 cells.Immunohistochemistry was performed detect expression...
Evidence has suggested that vascular endothelial growth factor (VEGF), a crucial in regulating progenitor cells (EPCs), plays central role keloid formation. However, the levels of circulating EPCs patients with have not yet been explored. The aim this study was to determine number keloid. Circulating (defined as CD45− CD34+CD133+VEGFR2+cells) and VEGF from 39 22 healthy controls (HCs) were assessed by flow cytometry ELISA, respectively. detectable peripheral blood plasma significantly higher...
It is anticipated that the rate of sexual transmission viruses could be substantially decreased by use topical chemical barrier methods. Chemical modification bovine (β-lactoglobulin (β-LG), major protein whey, led to generation a potent inhibitor (designated 3HP-β-LG) human immunodeficiency virus type 1 (HIV-1) infection which was also active against herpesviruses. Compounds intended for application prevent need maintain their antiviral activity at pH <<7, corresponding an acidic...
A hybrid attenuation correction technique (ACT) has been developed for /sup 18/F-FDG Total Body Positron Emission Tomography (PET). With a short transmission scan of the thorax, any time within few days isotope injection, it can correct in entire body. Segmentation, registration, and active contour finding techniques are applied to both emission images locate map major attenuating structures This eliminates need patient remain still from start end without added noise simultaneous or post...
Background: Paraspeckle component 1 (PSPC1) is overexpressed in various cancer and correlated with poor survival the patients. However, little known about its expression role progression of nasopharyngeal carcinomas (NPC). The purpose this study to examine PSPC1 NPC explore clinical prognosis radiation therapy. Methods: association clinicopathological features 109 patients was examined using partial correlation analysis. Cancer tissues were obtained prior treatment. All cases diagnosed...