Hongfu Sun

ORCID: 0000-0003-4638-8437
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Esophageal Cancer Research and Treatment
  • Cancer Immunotherapy and Biomarkers
  • Lung Cancer Research Studies
  • Nutrition and Health in Aging
  • Cancer survivorship and care
  • Colorectal and Anal Carcinomas
  • Radiomics and Machine Learning in Medical Imaging
  • Pancreatic and Hepatic Oncology Research
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Treatments and Mutations
  • Cancer-related gene regulation
  • Prostate Cancer Diagnosis and Treatment
  • Advanced Radiotherapy Techniques

Shandong First Medical University
2022-2025

Shandong Tumor Hospital
2022-2025

Second Hospital of Shandong University
2024

Shandong Academy of Chinese Medicine
2022

PURPOSE This multicenter, randomized, phase III clinical trial (Northern Radiation Oncology Group of China-002) focused on patients with oligo-organ metastatic non–small cell lung cancer (NSCLC) who have epidermal growth factor receptor ( EGFR ) mutations. We aimed to investigate whether first-line concurrent thoracic radiotherapy (TRT) and EGFR-tyrosine kinase inhibitors (TKIs), compared TKIs alone, could achieve better survival. MATERIALS AND METHODS The in the TKI plus TRT group received...

10.1200/jco.23.02075 article EN Journal of Clinical Oncology 2024-10-07

410 Background: Neoadjuvant chemotherapy or chemoradiotherapy followed by surgery is the standard of care for resectable locally advanced ESCC. SHR-1701, a new bifunctional fusion protein composed monoclonal antibody against PD-L1 fused with extracellular domain TGF-β receptor II, may enhance antitumor activity in combination neoadjuvant therapies ESCC patients (pts). The aim this phase II trial to determine safety and efficacy plus SHR-1701 esophagectomy pts Methods: Pts thoracic ESCC,...

10.1200/jco.2025.43.4_suppl.410 article EN Journal of Clinical Oncology 2025-01-27

Purpose To compare the difference between magnetic resonance imaging (MRI) and computed tomography (CT) in delineating target area of lung cancer with atelectasis. Method A retrospective analysis was performed on 15 patients accompanied by All positioning images were transferred to Eclipse treatment planning systems (TPSs). Six MRI sequences (T1WI, T1WI+C, T1WI+C Delay, 10 minutes, T2WI, DWI) registered CT. Five radiation oncologists delineated tumor boundary obtain gross volume (GTV)....

10.3389/fonc.2022.841771 article EN cc-by Frontiers in Oncology 2022-08-03

Although concurrent Chemoradiotherapy (cCRT) is presently the standard intervention for patients with inoperable, locally advanced Esophageal Squamous Cell Carcinoma (ESCC), it has been associated poor long-term survival outcomes. Notably, Immune Checkpoint Inhibitors (ICIs) improve of Cancer (EC) patients, manageable Adverse Effects (AEs). Herein, 90 residual pathology after radical simultaneous Radiotherapy (RT) inoperable/refused-to-operate ESCC were enrolled and randomized into two...

10.1080/14796694.2024.2432290 article EN cc-by-nc-nd Future Oncology 2024-11-26
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