A5016946221- Infant Nutrition and Health
- Neonatal Respiratory Health Research
- Infant Development and Preterm Care
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Diaphragmatic Hernia Studies
- Clinical Nutrition and Gastroenterology
- Neonatal and fetal brain pathology
- Infant Health and Development
- Gut microbiota and health
- Probiotics and Fermented Foods
- Intestinal Malrotation and Obstruction Disorders
- Prenatal Screening and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Viral gastroenteritis research and epidemiology
- Pulmonary Hypertension Research and Treatments
- Breastfeeding Practices and Influences
- Congenital limb and hand anomalies
- Cardiovascular Issues in Pregnancy
- Lymphatic Disorders and Treatments
- Gastrointestinal disorders and treatments
- Neuroscience of respiration and sleep
- Neonatal and Maternal Infections
- Cardiac Arrest and Resuscitation
- Pregnancy-related medical research
- Fetal and Pediatric Neurological Disorders
King Edward Memorial Hospital
2016-2025
The University of Western Australia
2015-2025
The Kids Research Institute Australia
2022-2025
Nanyang Technological University
2023
Baptist Memorial Hospital for Women
2023
UNSW Sydney
2023
Directorate of Health
2022
Indiana University School of Medicine
2022
Memorial Hospital
2022
Princess Margaret Hospital for Children
2013-2020
OBJECTIVES: The current Australian epidemiology of Kawasaki disease (KD) is poorly defined. Previous enhanced surveillance (1993–1995) estimated an incidence 3.7/100 000 <5 years. METHODS: We identified all patients hospitalized in Western Australia (current population ∼2.4 million) 1979 through 2009 with a discharge diagnosis KD. reviewed demographic, clinical, laboratory, and echocardiographic data from individual patient files derived age-specific estimates. KD was made using...
Health care professionals (HCPs) in neonatal intensive units (NICUs) are prone to significant stress, leading deleterious mental health effects. Recently, some studies have explored virtual reality (VR) immersion experience mitigate these risks. However, vary clinical settings, design and parameters. To report on the safety feasibility of VR busy tertiary NICU HCPs. Ten eligible HCPs without photosensitive epilepsy or cardiopulmonary disease participated. Participants underwent (intervention...
Mortality, necrotising enterocolitis (NEC), late onset sepsis (LOS) and feeding intolerance are significant issues for very preterm (< 32 weeks) extremely 28 infants. The complications of ≥ Stage II NEC [e.g. Resection the gangrenous gut, survival with intestinal failure, recurrent infections, prolonged hospital stay, long-term neurodevelopmental impairment (NDI)] impose a health burden. LOS also carries burden including NDI due to adverse effects inflammation on brain during critical phase...
Objective Evidence indicates that multistrain probiotics benefit preterm infants more than single-strain (SS) probiotics. We assessed the effects of SS versus triple-strain (TS) probiotic supplementation (PS) in extremely (EP) infants. Design EP (gestational age (GA) <28 weeks) were randomly allocated to TS or probiotic, assuring blinding. Reference (REF) group was placebo arm our previous trial. PS commenced with feeds and continued until 37 weeks’ corrected GA. Primary outcome time full...
(1) Background: The incidence of gestational diabetes mellitus (GDM) is rising globally. current evidence indicates that GDM, especially in conjunction with maternal overweight, can alter the composition infants' gut microbiota, potentially increasing risk inflammatory diseases, metabolic disorders, and neurodevelopmental issues later life. Probiotic supplantation early life might establish eubiosis mitigate future complications. To best our knowledge, no study has evaluated effects...
Organic acidemias (OAs) are heritable genomic abnormalities characterized by the absence or defects in critical enzyme(s), which result accumulation of abnormal and toxic organic acid metabolites.These metabolites can be detected blood and/or urine high levels.Organic have severe clinical manifestations, where most patients become symptomatic within neonatal period early infancy.Mildly affected cases may present later during adolescence adulthood following decompensation illness, surgery,...
OBJECTIVE: To compare outcomes of hospitalized preterm infants following previable prelabour rupture membranes (PPROM) at≤23 weeks gestation. METHODS: Retrospective cohort study admitted for intensive care, between January 2006 and December 2016 PPROM, was conducted. Short term clinical included severity respiratory morbidity, length hospital stay mortality. Neurodevelopment in survivors assessed using Bayley’s Scales Infant Development (3rd edition) at 24 months corrected age. RESULTS: A...
Abstract Objectives The purpose of this study was to characterise neonatal Staphylococcus aureus (SA) sepsis in Western Australia (WA) between 2001 and 2020 at the sole tertiary intensive care unit (NICU), examine risk factors for cohort, compare short- long-term outcomes control infants without any sepsis. Methods Retrospective cohort Neonatal Directorate King Edward Memorial Hospital (KEMH) Perth Children’s Hospital, using electronic databases patient medical records. Results overall...
Green gastric residuals (GR) are often considered as a sign of feed intolerance and discarded in preterm infants. Probiotics known to enhance tolerance To assess the composition (primary outcome) volume green GRs, feeding outcomes extremely (EP) infants probiotic trial, pale dark GRs first two weeks life from EP (<28 weeks) randomized controlled trial (RCT: SiMPro) single vs. three-strain probiotics was assessed. Feeding included time full feeds (TFF: 150 mL/kg/day) duration parenteral...