A5102003318- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Shape Memory Alloy Transformations
- Pediatric Hepatobiliary Diseases and Treatments
- Sleep and Wakefulness Research
- Esophageal and GI Pathology
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- Anesthesia and Sedative Agents
- Grouting, Rheology, and Soil Mechanics
- Colorectal Cancer Screening and Detection
- Sleep and related disorders
- Neuroscience and Neuropharmacology Research
- Anesthesia and Pain Management
- Biliary and Gastrointestinal Fistulas
- Respiratory Support and Mechanisms
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Anesthesia and Neurotoxicity Research
- Circadian rhythm and melatonin
- Dam Engineering and Safety
- Airway Management and Intubation Techniques
- Pancreatic function and diabetes
Showa University
2016-2025
Toyama Prefectural Central Hospital
1999-2024
Showa University Hospital
2024
Ministry of Land, Infrastructure and Transport
2020
Public Works Research Institute
2020
Kagawa University
2020
Akita Red Cross Hospital
2012-2020
Ministry of Land, Infrastructure, Transport and Tourism
2020
Shiga University of Medical Science
2019
Osaka International Cancer Institute
2018
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMigration behavior of inorganic anions in micellar electrokinetic capillary chromatography using cationic surfactantTakashi. Kaneta, Shunitz. Tanaka, Mitsuhiko. Taga, and Hitoshi. YoshidaCite this: Anal. Chem. 1992, 64, 7, 798–801Publication Date (Print):April 1, 1992Publication History Published online1 May 2002Published inissue 1 April 1992https://pubs.acs.org/doi/10.1021/ac00031a017https://doi.org/10.1021/ac00031a017research-articleACS...
Abstract Background A new circulating biomarker superior to carbohydrate antigen 19–9 (CA19-9) is needed for diagnosing pancreatobiliary cancer (PBca). The aim of this study was identify serum microRNA (miRNA) signatures comprising reproducible and disease-related miRNAs. Methods This multicenter involved patients with treatment-naïve PBca healthy participants. optimized processing conditions were evaluated using t -distributed stochastic neighbor embedding ( -SNE) visualization. Serum miRNA...
Severe constipation can cause ischemic bowel disease and other complications in older adults. However, its association with the formation of prostate abscesses has rarely been reported. An 80-year-old male recently presented to our center syncope, dehydration, constipation. Contrast-enhanced computed tomography (CT) revealed fecal impaction a hypodense lesion prostate. Despite no initial elevation inflammatory markers, patient later developed recurrent hypotension. Follow-up CT confirmed...
Clear cell adenocarcinomas (CA), unlike serous (SA) of the ovary, are often at stage I, resistant to platinum-based drugs and have a poor prognosis. The causes these differences unclear. In this study, in progression between CA SA were examined terms apoptosis-related tumor invasion-related factors. 16 cases reviewed. Excised tissues classified into primary or metastatic loci, expressions survivin, Bcl-2 matrix metalloproteinase-2 (MMP-2) each locus immunohistochemically assayed. Whether...
To investigate the hypothesis that interleukin (IL)-1β is involved in mediating localized electroencephalogram synchronization. We evaluated bilateral cortical electroencephalograms after unilateral local application of IL-1β onto somatosensory cortex rats. Furthermore, we investigated effects an inhibitor, IL-1 soluble receptor, on spontaneous sleep and rebound deprivation. University research laboratory. N/A. Rats Neither dose or receptor affected duration non-rapid eye movement rapid...
Orexins (OXs) regulate wakefulness, and a lack of OX Type-I receptors cause narcolepsy. selectively increases norepinephrine (NE) release from rat cerebral cortical slices, brain noradrenergic neurons are involved in the sleep-wakefulness cycle. Ketamine NE cortex. We hypothesized that would affect ketamine anesthesia's interactions with neuronal activity.We used Sprague Dawley rats. studied 1) vivo effects orexin A (OXA) SB-334867-A (Orexin-1 receptor antagonist) on ketamine-induced...
Neuropeptide S (NPS) and its receptor (NPSR) is a novel neuropeptide system that regulates arousal anxiety. A link between natural sleep general anesthesia has been suggested. Therefore, we hypothesized the NPS neuronal may also modulate anesthesia.The effects of intracerebroventricular [D-Cys(tBu)(5)]NPS, peptide NPSR antagonist, on ketamine thiopental time were measured in rats. Anesthesia was defined as interval loss righting reflex recovery.Intracerebroventricular 1 to 30 nmol...
This study investigated the feasibility of side-by-side (SBS) partially covered self-expandable metal stent (PCSEMS) placement for unresectable malignant hilar biliary obstruction (MHBO). We retrospectively analyzed 33 patients from a single center who underwent endoscopic drainage MHBO July 2013 to June 2015. In all with bilateral during complete intrahepatic cholangiograms, we performed SBS 6-mm diameter PCSEMS using an 8-French delivery system. All sphincterotomy. Generally, recurrent...
Smoking changes numerous alveolar macrophage functions and is one of the most important risk factors for postoperative pulmonary complications. The current study tested hypothesis that smoking impairs antimicrobial proinflammatory responses in macrophages during anesthesia surgery.The authors studied 30 nonsmoking patients propofol-fentanyl general anesthesia. Alveolar immune cells were harvested by bronchoalveolar lavage immediately 2, 4, 6 h after induction at end surgery. types cell...