A5101485733- Catalytic Processes in Materials Science
- Plasma Applications and Diagnostics
- Mass Spectrometry Techniques and Applications
- Gas Sensing Nanomaterials and Sensors
- Atmospheric chemistry and aerosols
- Analytical chemistry methods development
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Atmospheric and Environmental Gas Dynamics
- Ion-surface interactions and analysis
- Obesity, Physical Activity, Diet
- Advanced Chemical Sensor Technologies
- Cardiovascular Health and Disease Prevention
- Antimicrobial Resistance in Staphylococcus
- Antibiotics Pharmacokinetics and Efficacy
- Air Quality and Health Impacts
- Hydrocarbon exploration and reservoir analysis
- Laser-induced spectroscopy and plasma
- Birth, Development, and Health
- PI3K/AKT/mTOR signaling in cancer
- Carbon and Quantum Dots Applications
- Contact Dermatitis and Allergies
- Industrial Gas Emission Control
- Gastrointestinal Tumor Research and Treatment
- Chemical Reaction Mechanisms
Hebei Medical University
2021-2024
Fourth Hospital of Hebei Medical University
2021-2024
Shanghai University
2017-2024
Guangdong University of Technology
2020-2021
Jinan University
2020-2021
Shandong University
2014-2019
Shanghai University of Electric Power
2012
It has been argued that metabolically healthy obesity (MHO) does not increase cardiovascular disease (CVD) risk. This study examines the association of MHO with carotid intima-media thickness (cIMT), a proxy CVD risk, in children and adolescents.Data were available for 3,497 adolescents aged 6-17 years from five population-based cross-sectional studies Brazil, China, Greece, Italy, Spain. Weight status categories (normal, overweight, obese) defined using BMI cutoffs International Obesity...
BACKGROUND Plasma concentration monitoring is crucial for optimizing vancomycin use, particularly in patients the intensive care unit (ICU). However, reference interval plasma remains undetermined. AIM To evaluate correlations of area under curve (AUC0-24) and trough (Cmin) with efficacy nephrotoxicity ICU. METHODS A total 103 treated methicillin-resistant Staphylococcus aureus infections were analyzed this study. The associations clinicodemographic characteristics (including sex, age,...
Background: Imatinib is the first-line treatment for gastrointestinal stromal tumors; however, clinical prognosis and adverse reactions of patients vary owing to individualized discrepancies in plasma exposure. Methods: To determine safe interval steady-state trough concentrations (C min ) imatinib its active metabolite, N-demethyl (NDI), 328 samples from 273 treated with were retrospectively analyzed. C NDI tested, recorded. The association between , serious was evaluated. Results: range...
The clinical utility of screening for pediatric metabolic syndrome (MetS) in children and adolescents is still controversial. We examined the performance MetS vs. clustering cardiovascular risk factors (which are components MetS) predicting high carotid intima-media thickness (cIMT) adolescents.Participants included 2427 aged 6-17 years from population-based studies three countries (Brazil, China Italy). Pediatric was defined using either modified National Cholesterol Education Program Adult...
Ultrasensitive analysis of organic molecules is crucial for various fundamental research and applications. State-of-the-art techniques this purpose can achieve detection limits several hundred ppq (parts-per-quadrillion), while a higher sensitivity pursued constantly. To goal, we develop femtosecond laser assisted chemical ionization mass spectrometry. This technique combines the advantages ionization, either which enables subppt (parts-per-trillion) spectrometry molecules. The results...
Non-thermal plasma (NTP) has proven to be an effective approach for the removal of volatile organic compounds (VOCs). However, harmful by-products, produced during NTP-mediated VOCs, hinder practical applications this technology. It is necessary characterize by-products assess their health risks.A method proposed analyzing and evaluating VOCs in work. NTP generated by a coaxial dielectric barrier discharge (DBD) reactor was used model VOC, toluene, nitrogen. Organic products were...
LA-SPAMS was developed for online measurement of the size and chemical composition individual particles ablated from solid materials.
Abstract Proton transfer reaction mass spectrometry (PTR‐MS) is a mature technique for the real‐time measurement and monitoring of volatile organic compounds in atmosphere. In this paper, modified quantification method PTR‐MS was used to assess performance nonthermal plasma (NTP) reactor removal toluene which widely industrial production processes. Toluene 11 corresponding by‐products were tentatively identified quantified by proton time‐of‐flight spectrometer. The degradation dynamics...
The study of ion chemistry involving the NO2+ is currently focus considerable fundamental interest and relevant in diverse fields ranging from mechanistic organic to atmospheric chemistry. A very intense source was generated by injecting products dielectric barrier discharge a nitrogen oxygen mixture upstream into drift tube proton transfer reaction time-of-flight mass spectrometry (PTR-TOF-MS) apparatus with H3 O+ as reagent ion. intensity controllable related operation conditions ratio...
A new atmospheric pressure ionization method, plasmaspray ionization, termed as PSI, was developed to be an alternative ambient ion source for mass spectrometry. It comprises a plasma jet device and sample spray part. While the nonthermal strikes surface of stainless steel tube out capillary, sprayed will ionized with assistant auxiliary gas. Although PSI is little bit more complex than electrospray (ESI) in instrument, it shows both better linearity higher sensitivity organic compounds. For...
Objective: Imatinib is a first-line medicine for chronic myeloid leukemia (CML) and gastrointestinal mesenchymal stromal tumors (GIST). Co-administration of nifedipine may lead to drug-drug interactions that affect the clinical efficacy imatinib. are substrates cytochrome enzyme CYP3A4. This study aimed research pharmacokinetic effect on imatinib its metabolism N-desmethyl in rats. Method: Twenty healthy SD rats were randomly divided into two groups. The control group was administered by...
Objective: Tacrolimus, a calcineurin inhibitor (CNI), is the first-line treatment for chronic myeloid leukemia (CML) and advanced gastrointestinal stromal tumors (GIST). Imatinib tacrolimus are both substrates of hepatic enzymes CYP3A4/5 efflux transporter P-gp, so drug-drug interactions may occur during their co-administration treatment. Therefore, this study aimed to evaluate pharmacokinetic interaction between imatinib in rats. Methods: Rats were divided into groups I (30 mg/kg...