A5066479728- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Mobile Health and mHealth Applications
- Organ Transplantation Techniques and Outcomes
- Medical Imaging Techniques and Applications
- Organ Donation and Transplantation
- Digital Mental Health Interventions
- Transplantation: Methods and Outcomes
- Cardiac electrophysiology and arrhythmias
- Hemophilia Treatment and Research
- Liver Disease and Transplantation
- Lipoproteins and Cardiovascular Health
- Childhood Cancer Survivors' Quality of Life
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Global Cancer Incidence and Screening
- Respiratory viral infections research
- Adolescent and Pediatric Healthcare
- Vascular anomalies and interventions
- Infective Endocarditis Diagnosis and Management
- Renal and Vascular Pathologies
- Health, Environment, Cognitive Aging
- Heparin-Induced Thrombocytopenia and Thrombosis
University of Alberta
2024
Amsterdam University Medical Centers
2022
Scripps Research Institute
2015-2019
University of California, San Francisco
2019
Advanced Radiation Centers of New York
2009-2017
Columbia University
2016
La Jolla Alcohol Research
2015
Scripps Health
2015
University Medical Center Utrecht
2014
St. Luke's-Roosevelt Hospital Center
2013
This study sought to determine updated conversion factors (k-factors) that would enable accurate estimation of radiation effective dose (ED) for coronary computed tomography angiography (CTA) and calcium scoring performed on 12 contemporary scanner models current clinical cardiac protocols compare these methods the standard chest k-factor 0.014 mSv·mGy−1cm−1. Accurate ED from CT scans is essential meaningfully benefits risks different imaging strategies optimize test protocol selection....
Background. Mobile health and digital medicine technologies are becoming increasingly used by individuals with common, chronic diseases to monitor their health. Numerous devices, sensors, apps available patients consumers–some of which have been shown lead improved management outcomes. However, no randomized controlled trials conducted examine care costs, most failed provide study participants a truly comprehensive monitoring system. Methods. We prospective trial adults who had submitted...
The relationships between host factors, viral shedding, illness severity, and antibody response in respiratory syncytial virus (RSV)-induced bronchiolitis are poorly defined. These were prospectively evaluated 77 infants hospitalized with RSV multicenter, double-blind, placebo-controlled trials of immunoglobulin therapy. Severity was influenced by age risk factors but not neutralizing titer or the amount nasal secretions at enrollment. Virus recovery variable highest Viral shedding primary...
Background Atrial fibrillation (AF) is the most commonly encountered arrhythmia and associated with an elevated risk of stroke. Improving identification patients highest for AF to enable appropriate surveillance treatment, if necessary, critical reducing AF-associated morbidity mortality. Multiple common single nucleotide polymorphisms (SNPs) are unequivocally lifetime AF. In current study we aimed prospectively validate genetic score (GRS) in previously undiagnosed at Methods findings...
Three-dimensional rotational angiography (3DRA) is a relatively new but promising imaging technique in the paediatric catheterization laboratory. However, data on effective dose (ED) of this children are lacking. The purpose study to provide ED 3DRA and correlate with parameters readily available daily practice. Furthermore, effect dose-reducing techniques evaluated.Effective doses were calculated Monte Carlo PCXMC 2.0 14 patients who underwent total 17 3DRAs at our Median age was 5.7 years...
A wide range of personal wireless health-related sensor devices are being developed with hope improving health management. Factors related to effective user engagement, however, not well-known. We sought identify factors associated consistent long-term use the Scanadu Scout multi-parameter vital sign monitor among individuals who invested in device through a crowd-funding campaign. Email invitations join study were sent 4525 participants from US. Those completing baseline survey follow-up...
ABSTRACT Background Mobile health and digital medicine technologies are becoming increasingly used by individuals with common, chronic diseases to monitor their health. Numerous devices, sensors, apps available patients consumers – some of which have been shown lead improved management outcomes. However, no randomized controlled trials conducted examine care costs, most failed provide study participants a truly comprehensive monitoring system. Methods We prospective trial adults who had...
The success of solid organ transplantation is limited by ongoing problems with availability.The use extended cadaveric donors as well the living are both strategies used to overcome this shortage. One group potential that has not been previously reported those who have received an transplant. This type transplant was first described a “domino heart-lung and heart” (1). A combined performed in patient end-stage lung disease, but still had adequate heart performance. normal recipient then...
Many patients with von Willebrand disease (VWD) are treated on demand factor and VIII (FVIII) containing concentrates present VWF and/or FVIII plasma levels outside set target levels. This carries a risk for bleeding potentially thrombosis. Development of population pharmacokinetic (PK) model based is first step to more accurate on-demand perioperative dosing this concentrate.Patients VWD undergoing surgery in Academic Haemophilia Treatment Centers the Netherlands between 2000 2018 FVIII/VWF...
Abstract BACKGROUND Lipoprotein(a) [Lp(a)] is an inherited risk factor for cardiovascular disease that accompanied by a more severe coronary artery (CAD) phenotype and higher events. The objective of this study to clarify the association between Lp(a) plaque characteristics in asymptomatic patients. METHODS 373 consecutive patients were evaluated primary prevention CAD. Artificial intelligence quantitative CTA (AI-QCT) was used investigate relationship characteristics. Multivariable linear...
Coronary computed tomography angiography (CCTA) is often used to assess the extent and severity of atherosclerosis. A major limitation CCTA are densely calcified coronary plaques that obscure underlying lumen rendering assessment difficult. The purpose this study was evaluate hemodynamic importance lesions on in patients with low-to-intermediate likelihood artery disease.We studied 92 (64±10 years, 75% men) who underwent stress perfusion cardiovascular magnetic resonance (CMR). stenoses were...
Background: Three-dimensional rotational angiography (3DRA) is a relatively new but promising imaging technique in the pediatric catheterization laboratory. However, data on effective dose (E) of this are lacking, since they very time consuming to obtain. The purpose our study provide E 3DRA and correlate Ed parameters readily available daily practice.