A5018503273- Advanced Drug Delivery Systems
- 3D Printing in Biomedical Research
- Pharmaceutical studies and practices
- Drug Solubulity and Delivery Systems
- Advanced Sensor and Energy Harvesting Materials
- Diabetes Treatment and Management
- Micro and Nano Robotics
- Advanced MEMS and NEMS Technologies
- Microfluidic and Bio-sensing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Advancements in Transdermal Drug Delivery
- Neuroscience and Neural Engineering
- Dental Implant Techniques and Outcomes
- Protein purification and stability
- Pancreatic function and diabetes
- Lipid Membrane Structure and Behavior
- Wireless Body Area Networks
- Soft Robotics and Applications
- Advanced Biosensing Techniques and Applications
- Neurological disorders and treatments
- Infant Health and Development
- Head and Neck Surgical Oncology
- Vagus Nerve Stimulation Research
- Orthodontics and Dentofacial Orthopedics
- Gastroesophageal reflux and treatments
Georgia Institute of Technology
2023-2024
Emory University
2023-2024
The Wallace H. Coulter Department of Biomedical Engineering
2023-2024
Stanford University
2021-2023
Massachusetts Institute of Technology
2017-2022
Barzilai Medical Center
2021
Johns Hopkins University
2015-2018
Delivering fragile drugs to the gut Oral delivery is simplest and least invasive way deliver many pharmaceuticals, but medications, including insulin, cannot survive passage through stomach or gastrointestinal tract. Abramson et al. developed an ingestible vehicle that could self-reorient from any starting position so as attach gastric wall. Encapsulation of a spring in sugar casing allowed for triggered actuation biomolecules. The approach successfully provided active insulin pigs. Science...
Assessing the efficacy of cancer therapeutics in mouse models is a critical step treatment development. However, low-resolution measurement tools and small sample sizes make determining drug vivo difficult time-intensive task. Here, we present commercially scalable wearable electronic strain sensor that automates testing by continuously monitoring micrometer-scale progression or regression subcutaneously implanted tumors at minute time scale. In two models, our discerned differences tumor...
Body-conformal sensors and tissue-interfacing robotic therapeutics enable the real-time monitoring treatment of diabetes, wound healing, other critical conditions. By integrating drug-delivery devices, scientists engineers have developed closed-loop systems with on-demand therapeutic capabilities to provide just-in-time treatments that correspond chemical, electrical, physical signals a target morbidity. To functionality in vivo, utilize various low-power means communication reduce size...
An ingestible device injects probes into stomach tissue for electrical stimulation and potential treatment of gastroparesis.
Abstract Bioelectronic fibers hold promise for both research and clinical applications due to their compactness, ease of implantation, ability incorporate various functionalities such as sensing stimulation. However, existing devices suffer from bulkiness, rigidity, limited functionality, low density active components. These limitations stem the difficulty many components on one-dimensional (1D) fiber incompatibility conventional microfabrication methods (e.g., photolithography) with curved,...
Objective: The objective was to assess the outcome of graftless sinus floor augmentation associated with dental implant placement performed an system that has internal port and screw, combined osteotome technique. Method materials: Between 2012 2018, 722 titanium-aluminum-vanadium implants (Ti-6Al-4V ELI, diameter 3.75/4.20 mm) were placed in 331 patients. Implants 11.5 mm length inserted maxillae bone level ≤ 5 mm, 13.0-mm-long > 8 mm. In all cases, no graft materials or substitutes used...
Orbital fractures account for up to 40% of craniofacial injuries. In this article, the authors present transoral endoscopy-assisted plating technique treating orbital blowout (OBF). A retrospective analysis 56 cases treated with approach was performed. Immediate versus delayed surgery decision-making performed by using our 2-week algorithm. The surgical included only incisions, forced duction and "pulse" tests, osteotomy, endoscopic inspections, reduction a curved elevator an indwelling...
Abstract Healthcare professionals and scientists utilize tumor shrinkage as a key metric to establish the efficacy of cancer treatments. However, current measurement tools such CT scanners calipers only provide brief snapshots dynamic geometric changes occurring in vivo, they are unable characterize continuous micrometer-scale volumetric transformations transpiring at minute timescales. Here we present stretchable electronic strain sensor, with 10-micron scale resolution, capable...
Inspired by pollen grain microstructures, we have microfabricated disc shaped microscrapers capable of collecting tissue samples as they pass through the gastrointestinal (GI) tract. These possess a sufficient cell count to perform molecular pathology tests, which screen for potential tumorigenic mutations. The devices are coated in sharp tapered microbristles and small enough so that tens thousands can be potentially added an orally ingestible capsule; additionally, magnetic allow easy...