- Traditional Chinese Medicine Analysis
- Consumer Perception and Purchasing Behavior
- Medical Research and Treatments
- Inflammasome and immune disorders
- Vitamin C and Antioxidants Research
- Mechanical Circulatory Support Devices
- Video Coding and Compression Technologies
- Blockchain Technology Applications and Security
- Respiratory Support and Mechanisms
- Neurological Disease Mechanisms and Treatments
- Cancer, Hypoxia, and Metabolism
- Wastewater Treatment and Nitrogen Removal
- Inflammatory Biomarkers in Disease Prognosis
- Steroid Chemistry and Biochemistry
- Cardiac Valve Diseases and Treatments
- Advanced Data Compression Techniques
- Energy, Environment, Economic Growth
- Dietetics, Nutrition, and Education
- Error Correcting Code Techniques
- Geochemistry and Geologic Mapping
- Attachment and Relationship Dynamics
- Image and Video Quality Assessment
- Stroke Rehabilitation and Recovery
- Agriculture Sustainability and Environmental Impact
- Preterm Birth and Chorioamnionitis
Shandong University
2023-2025
Affiliated Hospital of Hangzhou Normal University
2020-2025
Qingdao University of Science and Technology
2024
Qingdao University of Technology
2024
Peking University
2024
Yunnan University
2024
TEDA International Cardiovascular Hospital
2024
ShanghaiTech University
2024
University of Manchester
2024
Zhengzhou University
2021-2023
ABSTRACT Aims To explore the association between body image, fear of childbirth and maternal‐fetal attachment mediating effects among different image profiles. Design A cross‐sectional study. Methods Pregnant women were recruited from obstetric outpatient clinics February 2022 October 2023. Face‐to‐face data collected using validated questionnaires. First, role birth was examined by calculating total scores. Then, latent analysis performed to identify profiles, relative mediation for in...
Background: We aimed to explore the effects of normative medical nutrition management based on health concepts weight control and maternal infant outcomes in women advanced age. Methods: Overall, 112 age were divided into group observation by random number table method. The was given routine intervention, concepts. nutritional status, delivery control, adverse pregnancy compared, mental state during evaluated State-Trait Anxiety Inventory Questionnaire (STAI). Results: status better than...
Gastroesophageal reflux disease (GERD), akin to sepsis, is mediated by inflammatory reactions and exhibits a strong correlation with intestinal dysbiosis. We sought examine whether these associations reflect causality using the Mendelian randomization (MR) mediation analysis. Genetic data were obtained from genome-wide association studies. Two-sample MR performed evaluate causal association, accompanied sensitivity analyses. Reverse direction was undertaken assess potential for reverse...
We report the development of an engineered aminotransferase for synthesis a key chiral intermediate anti-HIV drug Lenacapavir. Due to sterically demanding nature ketone substrate, substrate walking approach was adopted during directed evolution unlock desired activity starting from parent template (TA25) with no observable target reaction. Introduction 6 mutations into TA25 over 4 rounds led that affords amine product 90% conversion and >99% e.e. in favor S-enantiomer. The enzyme serves...
Thermal infrared remote sensing (TIRS) technology is intriguing for geothermal anomaly detection due to its time efficiency and cost-effectiveness. Land surface temperature (LST) derived from TIRS indicates potential anomalies. However, LST on different natural features, exhibiting relatively cold/hot anomalies in daytime nighttime, affected the identification of abnormal areas. The aim this study was highlight anomalous areas by integrating multi-view nighttime data. Specifically, winter...
Background: Early neurological deterioration (END) has been recognized as a serious complication after acute ischemic stroke. However, to date, the WORSEN score was only one scoring system specifically developed detect END events in stroke patients. The purpose of this study investigate score's utility China, and determine potential predictors Methods: Consecutive patients with admitted Department Neurology, Aerospace Center Hospital between March 2015 February 2017 were recruited into...
In recent years, user generated content (UGC) has become the dominant force in internet traffic. However, UGC videos exhibit a higher degree of variability and diverse characteristics compared to traditional encoding test videos. This variance challenges effectiveness data-driven machine learning algorithms for optimizing broader context scenarios. To address this issue, we propose Tri-Dynamic Preprocessing framework UGC. Firstly, employ an adaptive factor regulate preprocessing intensity....
There has been a growing trend in compressing and transmitting videos from terminals for machine vision tasks. Nevertheless, most video coding optimization method focus on minimizing distortion according to human perceptual metrics, overlooking the heightened demands posed by systems. In this paper, we propose preprocessing framework tailored tasks address challenge. The proposed incorporates neural preprocessor which retaining crucial information subsequent tasks, resulting boosting of...
Background Pyroptosis, a form of inflammatory programmed cell death, has recently emerged as pivotal factor in the pathogenesis myocardial ischemia/reperfusion (MI/R) injury. Despite its significance, effective therapeutic strategies targeting MI/R-induced pyroptosis remain elusive current clinical practice. Previous studies have demonstrated promising anti-inflammatory effects Angelica sinensis polysaccharide (ASP) context certain disorders. Objectives We aimed to investigate ASP on MI/R...
We report the development of an engineered P450 monooxygenase that mediates a chemo- and stereo-selective alkene epoxidation to generate key chiral precursor anti-tuberculosis drug delamanid. Screening in-house panel led identification BM3 variant, containing five mutations, with activity for target transformation. Over single round laboratory evolution gene shuffling, three further beneficial mutations were introduced leading order magnitude increase in de-sired activity, total turnover...