Michael J. Javorski

ORCID: 0009-0000-0014-6075
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About
Contact & Profiles
Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Structural Anomalies and Repair
  • Surgical Simulation and Training
  • Mechanical Circulatory Support Devices
  • Diabetic Foot Ulcer Assessment and Management
  • Cerebrovascular and Carotid Artery Diseases
  • Otolaryngology and Infectious Diseases
  • Nutritional Studies and Diet
  • Healthcare Policy and Management
  • Burn Injury Management and Outcomes
  • Cardiovascular Health and Disease Prevention
  • Wound Healing and Treatments
  • Vitamin D Research Studies
  • Anatomy and Medical Technology
  • Endoplasmic Reticulum Stress and Disease
  • PI3K/AKT/mTOR signaling in cancer
  • Blood Pressure and Hypertension Studies
  • Cardiac Valve Diseases and Treatments
  • Aortic aneurysm repair treatments
  • Simulation-Based Education in Healthcare
  • Clostridium difficile and Clostridium perfringens research
  • Heat shock proteins research
  • Esophageal and GI Pathology
  • Foreign Body Medical Cases

Cleveland Clinic
2019-2024

Faculty of 1000 (United States)
2022

RELX Group (United States)
2022

Loyola University Medical Center
2018

Loyola University Chicago
2016-2018

Boston University
2013

Boston College
2013

Gut barrier disruption is often implicated in pathogenesis associated with burn and other traumatic injuries. In this study, the authors examined whether therapeutic intervention mesalamine (5-aminosalicylic acid [5-ASA]), a common anti-inflammatory treatment for patients inflammatory bowel disease, reduces intestinal inflammation maintains normal integrity after injury. Male C57BL/6 mice were administered an approximately 20% TBSA dorsal scald resuscitated either 1 ml saline or 100 mg/kg of...

10.1097/bcr.0000000000000396 article EN Journal of Burn Care & Research 2016-01-01

ObjectivesTo identify preoperative predictors of postcardiotomy cardiogenic shock in patients with ischemic and nonischemic cardiomyopathy evaluate trajectory postoperative ventricular function.MethodsFrom January 2017 to 2020, 238 ejection fraction <30% (206/238) or 30% 34% at least moderately severe mitral regurgitation (32/238) underwent conventional cardiac surgery Cleveland Clinic, 125 113 cardiomyopathy. Preoperative was 25 ± 4.5%. The primary outcome shock, defined as need for...

10.1016/j.jtcvs.2024.02.025 article EN cc-by-nc-nd Journal of Thoracic and Cardiovascular Surgery 2024-03-05

The baroreceptor at the carotid body plays an important role in hemodynamic autoregulation. Manipulation of during endarterectomy (CEA) or radial force from artery angioplasty and/or stenting (CAS) may cause both intraoperative and postoperative instability. purpose this study is to evaluate long-term effects CEA CAS on blood pressure (BP), heart rate (HR), subsequent changes antihypertensive medications.A retrospective chart review was performed identify patients who underwent between 2009...

10.1177/1538574419828088 article EN Vascular and Endovascular Surgery 2019-02-11

The use of cardiopulmonary bypass (CPB) in cardiac surgery often leads to a systemic inflammatory response. Up 25% patients undergoing CPB for are reported develop vasoplegic syndrome the acute postoperative period, which refractory vasopressors. purpose this study is assess vitamin D deficiency as risk factor vasoplegia after using CPB. We performed retrospective review 1322 adult requiring Forty-six with previously recorded 25-hydroxy (25(OH)D) levels within 6 months met conditions study....

10.1177/1076029618772357 article EN cc-by-nc Clinical and Applied Thrombosis/Hemostasis 2018-05-06

Introduction: Prevention of atherosclerosis should be started in children or young adults. Thus, we need adequate predictive tools to target high-risk individuals developing CVD diabetes for preventive activities. Obesity people aged >40 y.o. was shown independent but less strong risk factor than arterial hypertension (AH) hypercholesterolemia.

10.1093/eurheartj/eht310.4362 article EN European Heart Journal 2013-08-02

Morning Report is a time-honored tradition where physicians-in-training present cases to their colleagues and clinical experts collaboratively examine an interesting patient presentation. The section seeks carry on this by presenting patient’s chief concern story, inviting the reader develop differential diagnosis discover alongside authors of case.This report examines case 73-year-old woman who was walking her car when she suddenly felt weak fell backward, hitting head. Using questions,...

10.1056/evidmr2300254 article EN NEJM Evidence 2023-11-28

Traumatic injury, specifically burn remains a prominent medical problem due to the prevalence of secondary, burn-induced complications sepsis and multiple organ dysfunction syndrome. These arise as result gut barrier breakdown following injury. As harbors trillions resident bacteria, any compromise in integrity would allow for bacteria or bacterial products gain access extraintestinal sites potentiating systemic infections inflammation associated with Both experimental human data provide...

10.26859/jnnsci.v2i01.9600 article EN Journal of Nature and Natural Sciences 2017-01-25

Integrated cardiothoracic surgery (CTS) and vascular (VS) residents must achieve operative independence in fewer years compared with traditional training paradigms. Developing a strong foundation early from which to build technical skills is of paramount importance. We hypothesized that intensive simulation performed by CTS VS junior would accelerate skill progression improve confidence. In July 2021, 7 post-graduate year (PGY)-1 5 PGY-2 integrated programs at single institution participated...

10.1016/j.avsurg.2022.100140 article EN cc-by-nc-nd Annals of Vascular Surgery - Brief Reports and Innovations 2022-10-17
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