A5101639375- Photonic and Optical Devices
- Optical Systems and Laser Technology
- Advanced Fiber Laser Technologies
- Liver Disease Diagnosis and Treatment
- Semiconductor Lasers and Optical Devices
- HIV Research and Treatment
- Optical Coatings and Gratings
- Gut microbiota and health
- Solid State Laser Technologies
- Vitamin D Research Studies
- Veterinary medicine and infectious diseases
- HIV-related health complications and treatments
- HIV/AIDS Research and Interventions
- Advanced optical system design
- Optical Network Technologies
- Photorefractive and Nonlinear Optics
- Digestive system and related health
- thermodynamics and calorimetric analyses
- Optical measurement and interference techniques
- Liver physiology and pathology
- Photonic Crystal and Fiber Optics
- Pancreatitis Pathology and Treatment
- Immunotherapy and Immune Responses
- Thermal Radiation and Cooling Technologies
- Magneto-Optical Properties and Applications
Industrial Technology Institute
2025
Tianjin People's Hospital
2023-2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Zhongshan Hospital
2024
Fudan University
2024
Sun Yat-sen University
2024
Second Affiliated Hospital of Zhejiang University
2021-2022
Zhejiang Cancer Hospital
2021
University of Shanghai for Science and Technology
2020-2021
Hainan General Hospital
2021
Colorectal cancer (CRC) is one of the most common malignant tumors and associated with Fusobacterium nucleatum (F. nucleatum, Fn) infection. In this study, we explored role F. in CRC metastasis. Our results showed that abundance was enriched feces patients tended to increase stage IV compared I metastatic CRC. Tumor-derived CCL20 activated by not only increases metastasis, but also participates reprograming tumor microenvironment. promoted macrophage infiltration through activation...
p38 mitogen-activated protein kinases are important inflammatory factors. p38α alteration has been implicated in both human and mouse disease models. Therefore, we aimed to characterize the cell type-specific role of non-alcoholic steatohepatitis (NASH).Human liver tissues were obtained from 27 patients with fatty (NAFLD) 20 control individuals. NASH was established compared between hepatocyte-specific knockout (p38αΔHep), macrophage-specific (p38αΔMΦ) wild-type (p38αfl/fl) mice fed high-fat...
The retinoic acid-inducible gene I product (RIG-I) is a cellular sensor of RNA virus infection that regulates the beta interferon (IFN-beta) response. nucleoproteins (NP) arenaviruses are reported to antagonize IFN response by inhibiting regulatory factor 3 (IRF-3). Here, we demonstrate Z proteins four New World (NW) arenaviruses, Guanarito (GTOV), Junin (JUNV), Machupo (MAVC), and Sabia (SABV), bind RIG-I, resulting in downregulation IFN-beta We show expression NW arenavirus inhibits mRNA...
Quantum entanglement is a vital resource in quantum information processing. High-dimensional offers advantages that classical systems cannot surpass, particularly enhancing channel capacity, improving system noise resilience, and increasing sensitivity to external environments. The construction of multimode the spectral domain well-suited for fiber-optic systems. Here, we present straightforward scheme generating frequency-bin using semiconductor chip through simple mode conversion. A...
Incomplete immune recovery in people living with HIV/AIDS (PLWHA) remains an important clinical challenge the lack of effective strategy currently available to restore their T-cell response. This study aimed evaluate effect Albuvirtide (ABT) on immunological non-responders (INRs) and attempted explore potential mechanisms ABT functionality cells.
Objective: As of date, Kimura disease (KD) has an unclear etiology, no accepted diagnostic standard, and definite treatment regimen. In this study, clinical pathological laboratory characteristics regimens patients with KD different tumor sizes status recurrence were analyzed. This was performed to identify the factors, which determine size recurrence, effective methods for KD. Methods: A total 33 hospitalized a diagnosis enrolled in study. Results: There 15 (45.5%) maximum diameter <3 cm....
The intestinal epithelial barrier plays an important role during human immunodeficiency virus (HIV) disease progression. However, the extent to which is damaged in immunological non-responders (INRs) and responders (IRs) largely unknown. In this study, we investigated compared levels of gland damage related molecules, including tight junction protein claudin-1, apoptosis marker caspase-3, HIV DNA, CD4+ T cell count, inflammation tumor necrosis factor-α (TNF-α) among IRs (n = 10), INRs 8),...
Antiretroviral therapy (ART) prolongs lifespan and decreases mortality of HIV infected patients. However, many patients do not achieve optimal immune reconstitution. The influence non-optimal recovery on non-AIDS related diseases is well defined in aged HIV-infected receiving ART.A retrospective study was conducted at Tianjin Second People's Hospital, China to evaluate the association an inadequate immunological response ≥60 years age virally suppressed for least 2 by ART.The included (n =...
Livedoid vasculopathy (LV) is a chronic prothrombotic disease of cutaneous micro-circulation resulting in ischemia and infarction. As rare disease, LV has an estimated incidence ten cases per million. Not only correct diagnosis but also effective treatments are very difficult for patients with LV. Due to the lack large-scale studies this poses great challenge doctors, existing treatment always been individual attempt off-label application. The main goals avoid repeated occurrence active...
An InP-based long wavelength velocity-matched distributed photodetector with metal-semiconductor-metal photodiodes is experimentally demonstrated. A 3 dB bandwidth of 18 GHz and an external quantum efficiency 0.42 A/W have been achieved.
Low-energy electron-beam (e-beam) lithography using ZEP-520 as a positive resist has been investigated in the energy range between 0.5 and 20 keV. The interaction electrons resist, its effect on exposure dose penetration depth of have studied function electron energy. At 10 keV ~ energy, we were able to achieve line gratings about 25 nm width 80 pitch films 180 nm-thickness silicon substrate. It is found that main limitation achieving high resolution dense pattern at low forward scattering...
// Lina Fan 1,* , Xuegang Hu 2,* Shihan Lin 2 Wentu Zhou 1 Sheng Fu and Hongbing Lv Department of Oral Maxillofacial Surgery, Fuzhou General Hospital Nanjing Command, PLA, Fuzhou, China School Stomatology, Fujian Medical University, * These authors have contributed equally to this work Correspondence to: Fu, email: Lv, Keywords : oral squamous cell carcinoma, three-dimensional conformal radiotherapy, concurrent preoperative chemotherapy, paclitaxel nedaplatin Received October 17, 2016...
Studies assessing the gut mucosal immune balance in HIV-infected patients using intestinal samples are scarce. In this study, we used specimens from ileocecal region of seven immunological nonresponders (INRs), nine responders (IRs), and six HIV-negative controls. We investigated T helper 17 (Th17) regulatory (Treg) cell counts their ratio, zonula occludens-1 (ZO-1), fatty acid-binding protein (I-FABP), tumor necrosis factor-α, CD4
The predecessor of China Optics was and Applied Digest, which founded in 1985. At that time, it the only retrieval journal field optics China. end 2008, Digest renamed
非机械式激光光束扫描系统具有体积小、重量轻、易集成等优势,在激光雷达、激光武器和激光通信等领域具有较大的应用前景,其通光口径决定着设备的工作距离、扫描精度和目标摧毁能力。基于液晶偏振光栅设计了一种全电控制的大口径激光光束扫描系统。采用液晶偏振光栅和液晶空间光调制器的协同工作方式,实现光束的大角度连续扫描;设计了光束扫描系统,并重点分析了级联液晶偏振光栅组的控制策略,给出了具体控制方法。最后,进行了激光光束的初步扫描实验,实现了70 mm口径光束在−16.575°~16.575°的偏转。该研究结果为激光光束的非机械式扫描控制提供了技术支撑,并在大口径激光扫描系统应用方面进行了初步探索。