Yadong Chen

ORCID: 0009-0000-5523-593X
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About
Contact & Profiles
Research Areas
  • Aquaculture disease management and microbiota
  • Invertebrate Immune Response Mechanisms
  • MicroRNA in disease regulation
  • Immune Response and Inflammation
  • Antimicrobial Peptides and Activities
  • Complement system in diseases
  • Cancer-related molecular mechanisms research
  • Genetic and phenotypic traits in livestock
  • Marine Bivalve and Aquaculture Studies
  • Aquaculture Nutrition and Growth
  • Mosquito-borne diseases and control
  • Genetic diversity and population structure
  • Genomics and Phylogenetic Studies
  • Identification and Quantification in Food
  • Facial Trauma and Fracture Management
  • Extracellular vesicles in disease
  • Reconstructive Surgery and Microvascular Techniques
  • Physiological and biochemical adaptations
  • International Relations and Foreign Policy
  • interferon and immune responses
  • Plant Stress Responses and Tolerance
  • Vibrio bacteria research studies
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Circular RNAs in diseases
  • Reproductive biology and impacts on aquatic species

Chinese Academy of Fishery Sciences
2015-2024

Shanghai Ocean University
2023-2024

Qingdao National Laboratory for Marine Science and Technology
2015-2023

Laoshan Laboratory
2023

Marine Biology Institute of Shandong Province
2021-2023

Ministry of Agriculture and Rural Affairs
2021-2022

Qingdao University
2017-2021

China Pharmaceutical University
2020

Zhejiang University
2018-2019

Dalian Ocean University
2014-2015

Drought stress significantly limits cotton growth and production due to the necessity of water at every stage crop growth. Hence, it is essential identify tolerant genetic resources understand mechanisms drought tolerance in economically socially important plants such as cotton. In this study, molecular physio-biochemical investigations were conducted by analyzing different parameters following standard protocols three species, namely TM-1 (Gossypium hirsutum), Zhongmian-16 arboreum),...

10.3390/ijms19092636 article EN International Journal of Molecular Sciences 2018-09-06

Drought is one of the most important abiotic stresses that seriously affects cotton growth, development, and production worldwide. However, molecular mechanism, key pathway, responsible genes for drought tolerance incotton have not been stated clearly. In this research, high-throughput next generation sequencing technique was utilized to investigate gene expression profiles three species (Gossypium hirsutum, Gossypium arboreum, barbadense L.) under stress. A total 6968 differentially...

10.3390/ijms20092076 article EN International Journal of Molecular Sciences 2019-04-27

Background: Inflammation and steatosis are the main pathological features of alcoholic liver disease (ALD), in which, inflammation is one critical drivers for initiation development steatosis. NIK, an inflammatory pathway component activated by cytokines, was suspected to link hepatic during ALD. However, underlying pathogenesis not well-elucidated. Methods: Alcoholic induced mice chronic-plus-binge ethanol feeding. Both loss- gain-of-function experiments hepatocyte-specific deletion,...

10.7150/thno.40149 article EN cc-by Theranostics 2020-01-01

Single nucleotide polymorphism (SNP) arrays are a powerful genotyping tool used in genetic research and genomic breeding programs. Japanese flounder (Paralichthys olivaceus) is an economically-important aquaculture flatfish many countries. However, the lack of high-efficient tools has impeded programs for flounder. We developed 50K SNP array, "Yuxin No. 1," report its utility selection (GS) disease resistance to bacterial pathogens. screened more than 42.2 million SNPs from whole-genome...

10.1016/j.eng.2020.06.017 article EN cc-by-nc-nd Engineering 2020-08-01

Sexual size dimorphism (SSD) is the difference in segments or body between sexes prevalent various species. Understanding genetic architecture of SSD has remained a significant challenge owing to complexity growth mechanisms and sexual influences among The Chinese tongue sole ( Cynoglossus semilaevis ), which exhibits female-biased sex reversal from female pseudomale, an ideal model for exploring mechanism at molecular level. present study aimed integrate transcriptome methylome analysis...

10.3389/fcell.2021.743722 article EN cc-by Frontiers in Cell and Developmental Biology 2021-12-02

Heat shock proteins 70 (HSP70s) are known to play essential roles in organisms' response mechanisms various environmental stresses. However, no systematic identification and functional analysis has been conducted for HSP70s the turbot (Scophthalmus maximus), a commercially important worldwide flatfish. Herein, 16 HSP70 genes unevenly distributed on nine chromosomes were identified at genome-wide level. Analyses of gene structure, motif composition, phylogenetic relationships provided...

10.3390/ijms24076025 article EN International Journal of Molecular Sciences 2023-03-23

As the Russian sturgeon (Acipenser gueldenstaedtii) is an important food and main source of caviar, it necessary to discover genes associated with its sex differentiation. However, complicated life maturity cycles restrict accurate identification in early development. To generate a first look at specific sex-related genes, we sequenced transcriptome gonads different development stages (1, 2, 5 yr old stages) next-generation RNA sequencing. We generated >60 million raw reads, filtered reads...

10.1152/physiolgenomics.00113.2015 article EN Physiological Genomics 2016-05-07

Infectious diseases have caused dramatic production decline and economic loss for fish aquaculture. However, the poor understanding of disease resistance severely hampered prevention. Chinese tongue sole (Cynoglossus semilaevis) is an important flatfish suffering from vibriosis. Here we used genomic, transcriptomic experimental approaches to investigate molecular genetic mechanisms underlying vibriosis resistance. A genome-wide comparison revealed that genes under selective sweeps were...

10.3389/fimmu.2022.974604 article EN cc-by Frontiers in Immunology 2022-09-29
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