A5100386287- Bacteriophages and microbial interactions
- Microbial infections and disease research
- Antimicrobial Peptides and Activities
- Polyamine Metabolism and Applications
- Streptococcal Infections and Treatments
- Aquaculture disease management and microbiota
- Bacterial biofilms and quorum sensing
- Probiotics and Fermented Foods
- CRISPR and Genetic Engineering
- Antibiotic Resistance in Bacteria
- Biochemical and Structural Characterization
- Phytochemicals and Antioxidant Activities
- RNA and protein synthesis mechanisms
- Antimicrobial Resistance in Staphylococcus
- Protein Hydrolysis and Bioactive Peptides
- RNA Interference and Gene Delivery
- Neonatal and Maternal Infections
- Postharvest Quality and Shelf Life Management
- Glycosylation and Glycoproteins Research
- Escherichia coli research studies
- Plant Pathogenic Bacteria Studies
- Neuroendocrine regulation and behavior
- Bacillus and Francisella bacterial research
- Infections and bacterial resistance
- Olfactory and Sensory Function Studies
Ministry of Agriculture and Rural Affairs
2016-2025
Shaanxi Normal University
2024-2025
Inner Mongolia Agricultural University
2024-2025
Anhui Agricultural University
2024-2025
Zhejiang University
2022-2025
Ministry of Science and Technology of the People's Republic of China
2018-2024
Center of Hubei Cooperative Innovation for Emissions Trading System
2015-2024
Huazhong Agricultural University
2015-2024
Shanxi Medical University
2024
Guangdong Medical College
2023-2024
In this study, the physicochemical properties, antioxidant capacity, and volatile compounds of juices different guava cultivars before after pectinase treatment were evaluated. The results showed that juice small fragrant (SF) cultivar exhibited highest ascorbic acid concentration (1761.09 mg/L), contents total phenolics (329.52 mg GAE/L) flavonoids (411.13 RE/L) both found in watermelon red (WR) cultivar. After treatment, yield titratable acid, sugar components, flavonoids, capacity levels...
Control of biogenic amines (BAs) is critical to guarantee the safety fermented meat products. The aim this study evaluate BAs formation and degradation abilities lactic acid bacteria from Chinese bacon obtain beneficial candidate for control. Seven were selected typical products, identified as Lacbacillus curvatus by 16S rDNA analysis. Then, genes analysis high performance liquid chromatography (HPLC) performed as-selected strains. All L. strains confirmed harbor encoding tyrosine...
Although antimicrobial peptides (AMPs) hold tremendous promise in overcoming the threats of multidrug resistance, main obstacle to successful therapeutic applications is their poor stability. Various synthetic strategies such as unnatural amino acids and chemical modifications have made advances for improving this problem. However, complicated synthesis often greatly increases cost production. Here, we show that a series novel peptides, designed by combining an α-helical coiled coil model,...
Significance Bacteria can produce β-lactamases, enzymes that destroy β-lactam antibiotics and thereby resist these potent target cell wall synthesis. Production of β-lactamases is often controlled by β-lactam-induced perturbations in the wall. Here, we have identified a new mechanism controlling β-lactamase production. We found signaling system which membrane-associated histidine kinase directly binds β-lactams, triggering expression resistance to antibiotics. Direct sensing may enable...
The increasing demand for natural resources due to urban growth has led sharp conflicts between land and environmental protection, causing problems such as decrease in the carbon storage of terrestrial ecosystems. To achieve sustainable development, China implemented spatial regulation restrict growth, but there have been various among multiple plans. In this study, we explored impact on under integrated Wuhan, by combining SLEUTH InVEST (Integrated Valuation Environmental Services...
Biogenic amines (BAs) in sausages represent a health risk for consumers, and thus investigating the BAs accumulation mechanism is important to control BAs. In this study, profiles of 16 typical Chinese sausage samples were evaluated, 8 kinds common detected from different samples. As whole, contents majority within safe dosage range, except that total histamine concentrations sample HBBD above toxic levels. Furthermore, bacterial fungal communities investigated by high-throughput sequencing...
Colistin is a last-line antibiotic against Gram-negative multidrug-resistant bacteria, but the increased resistance poses huge challenge to this drug. However, mechanisms underlying such are largely unexplored. The present study first identified mutations of two genes encoding AceF subunit pyruvate dehydrogenase (PDH) and TetR family transcriptional regulator in colistin-resistant Vibrio alginolyticus (VA-RCT ) through genome sequencing. Then, gas chromatography-mass spectroscopy-based...
Sanhua plum is difficult to dehydrate because of its epicuticular wax and dense pulp. Therefore, it necessary pretreat enhance dehydration efficiency. In this study, ultrasound-assisted osmotic pretreatment was used for plum, the effect on drying characteristics quality properties investigated. The results showed that ultrasound significantly increased water loss solid gain during dehydration. Furthermore, treated with reduced time, improved rate, effective diffusivity. low intensity...
Abstract Tigecycline is regarded as the last line of defense to combat multidrug-resistant Klebsiella pneumoniae . However, increasing utilization has led rising drug resistance and treatment failure. Here, we design a D-alpha tocopheryl polyethylene glycol succinate-modified S-thanatin peptide-functionalized nanorods based on calcium phosphate nanoparticles for tigecycline delivery pneumonia therapy caused by tigecycline-resistant After incubation with bacteria, fabricated can enhance...
Litchi pomace, a by-product of litchi processing, is rich in dietary fiber. Soluble and insoluble fibers were extracted from fiber was modified by ultrasonic enzymatic treatment to obtain soluble fibers. The structural, physicochemical, functional properties the samples evaluated compared. It found that all displayed typical polysaccharide absorption spectra, with arabinose being most abundant monosaccharide component. pomace morphologically fragmented relatively smooth, high swelling...
The aim of the current study was to analyse distribution antimicrobial drug resistance (AMR) among Pseudomonas aeruginosa (P. aeruginosa, PA) isolates from Guangdong Provincial People's Hospital (GDPH) 2017 2021, and impact COVID-19 outbreak on changes in clinical rate P. establish guidelines for empiric therapy. Electronic data registry records 2021 were retrospectively analysed AMR strains GDPH. identified by VITEK 2 Compact MALDI-TOF MS, MIC method or Kirby-Bauer antibiotic susceptibility...
Escherichia coli K‐12 carries a gene for protein denoted ClyA or SheA that can mediate cytolytic phenotype. The is not expressed at detectable levels in most strains of E. , but overproduction suitable purification was accomplished by cloning the structural an hns mutant strain. Highly purified cytotoxic to macrophage cells culture and caused detachment lysis mammalian cells. Results from osmotic protection assays were consistent with suggestion formed pores diameter up 3 nm. Using...
Actinobacillus pleuropneumoniae is the etiologic agent of porcine contagious pleuropneumonia, a cause considerable world wide economic losses in swine industry. We sequenced complete genome A. pleuropneumoniae, JL03, an isolate serotype 3 prevalent China. Its single chromosome 2,242,062 base pairs containing 2,097 predicted protein-coding sequences, six ribosomal rRNA operons, and 63 tRNA genes. Preliminary analysis genomic sequence functions encoded proteins not only confirmed present...
Porcine beta-defensin 2 (PBD-2) which is a member of the family antimicrobial peptides, widely expressed in pig organs with broad spectrum bactericidal activities confirmed vitro. We previously demonstrated that transgenic (TG) pigs overexpressing PBD-2 could resist infection by porcine pathogen Actinobacillus pleuropneumoniae. In this study, roles protecting against bacterial were further investigated. The biochemical indexes blood sample, body weights, histological morphologies and weights...
The reduction of carbon emissions from land use (CELU) is critical for China to achieve neutrality, which may be greatly facilitated by trading policies. Previous studies the emission effects policies focused mostly on source emissions, and there a lack research comprehensive perspective sources sinks. Understanding effect CELU help improve evaluation system policies, as well provide important implications construction China’s market in context global neutrality. Here, based current...
Bisphenol A (BPA) is widely used to harden plastics and polycarbonates causes serious toxic effects in multiple organs, including the intestines. Selenium, as an essential nutrient element for humans animals, exhibits a predominant effect various physiological processes. Selenium nanoparticles have attracted more attention due their outstanding biological activity biosafety. We prepared chitosan-coated selenium (SeNPs) further compared protective effects, investigated underlying mechanism of...
Pathogenic bacteria have evolved many strategies to evade surveillance and attack by complements. Streptococcus suis is an important zoonotic pathogen that infects humans pigs. Hyaluronidase (HylA) has been reported be a potential virulence factor of S. suis. However, in this study, it was discovered the genomic region encoding HylA virulent strain SC19 other ST1 strains truncated into four fragments when aligned with containing intact possessing hyaluronidase activity. As result, had no...
The mesolimbic dopamine (DA) system has been implicated in pair bond formation. However, involvements of DA release, real time activities, and electrophysiological activities D1/D2 medium spiny neurons (MSNs) the nucleus accumbens (NAc) shell bonding remain unclear. This work verified that male mandarin voles after released higher levels NAc displayed D1 MSNs activity lower D2 upon sniffing their partners compared to an unknown female. Moreover, induced differential alterations both synaptic...