Surface properties of rare-earth (RE) doped ceria (RE = Sm, Gd, Pr, and Tb) were investigated by UV (325 nm) visible (514, 633, 785 Raman spectroscopy, combined with UV-vis diffuse reflectance high-resolution transmission electron microscopy, X-ray photoelectron spectra techniques. It was found that the optical absorption property samples, wavelength detecting laser line, inhomogeneous distribution dopants significantly affected obtained surface information, namely, peak intensity shape at...

The objective of this study was to investigate the differences in fatty acid composition human breast milk from Holstein cows, Jersey Saanen goats, and humans at different lactation period find possible substitute for milk. In study, milk, were collected stages. Gas chromatography (GC-MS) used determine goat's cow's cows stages lactation. Pearson correlation analysis analyze between acids. results show that types relative contents acids varied among varieties same animals have varying...

The nutritional value of goat milk is determined by the composition its fatty acids, with particular importance placed on role unsaturated acids in promoting human health. CircRNAs have been known to affect acid metabolism through different pathways. In this study, high-throughput sequencing was employed construct expression profiles mammary tissue harvested during dry period and peak lactation stages dairy goats. Differentially expressed circRNAs mRNAs were screened, revealing significantly...

The composition of fatty acids plays a key role in regulating milk flavor and quality. Therefore, to improve the quality milk, it is particularly important study regulatory mechanism acid metabolism dairy cows. In this study, expression profiles at non-lactation, peak-lactation, mid-lactation late-lactation were constructed by high-throughput sequencing. Considering non-lactation as control group other points experimental groups, differentially expressed genes screened. ELOVL5 was...

Biotransformation of betulonic acid (1) by Rhizopus arrhizus CGMCC 3.868 resulted in the production 16 new (3, 5, 6, and 9-21) five known compounds. Structures compounds were established analysis spectroscopic data. Hydroxylation, acetylation, oxygenation, glycosylation, addition reactions involved C-20-C-29 double bond. Antineuroinflammatory activities obtained NO tested lipopolysaccharides-induced BV-2 cells. Compared with substrate acid, biotransformation products 3, 8, 9, 14, 21...

Lead, the most widely used heavy metal in industry, is detrimental to human health if exposed living and occupational environment. Although several studies have been conducted on lead exposure, little has reported its harm mammary gland mechanisms. In view of this, our study first verify that exposure could promote apoptosis inflammation mouse tissue (in vivo) cow epithelial cells vitro). After establishing a model, expression profile was constructed by high-throughput sequencing technology....

Milk, known for its high content of short- and medium-chain fatty acids unsaturated acids, has attracted substantial attention due to nutritional health value. The regulation acid metabolism by non-coding RNAs become a subject growing attention, particularly in relation production at the transcriptional/epigenetic post-transcriptional levels. This study established circRNA-11228/miR-103/INSIG1 (insulin-inducible gene) regulatory network using methods such as qRT-PCR, dual luciferase...

The regulatory mechanisms governing metabolism of fatty acids in cow mammary gland are crucial for establishing relationships between milk quality and acid content. Both, microRNAs (miRNAs) protein-coding genes important factors involved the regulation fat synthesis. In this study, high-throughput sequencing miRNAs mRNAs bovine tissue was performed during peak lactation (3 samples) late periods to characterize expression profiles. Differential (DE) analyses miRNA mRNA miRNA-mRNA pathway...

采用浸渍法制备了不同V2O5负载量(分别为5%和15%)的V2O5/CeO2催化剂.利用不同激发波长(514和325nm)的Raman光谱,结合X射线衍射(XRD)、紫外-可见漫反射(UV-Vis DRS)和N2物理吸附技术,考察了V2O5/CeO2催化剂中V2O5和载体CeO2之间的固相反应.结果表明:催化剂在300℃焙烧时,V2O5与CeO2反应生成CeVO4,升高温度有利于同相反应的发生.样...

Objective: There is a strong relationship between the content of beneficial fatty acids in milk and fat metabolic activity mammary gland. To improve quality, it therefore necessary to study acid metabolism bovine gland tissue. In adipose tissue, peroxisome proliferator-activated receptor gamma (PPARG), core transcription factor, regulates gene network determines deposition. However, its regulatory effects on during lactation have rarely been reported.Methods: Transcriptome sequencing was...

MicroRNAs (miRNAs) are a class of small RNA genes with important roles in cancer biology regulation. There considerable studies regarding the microRNA-505-3p (miR-505-3p) development and progression, but function miR-505-3p epithelial ovarian (EOC) has not been fully clarified. Comparative analysis miRNA expression data set was used to select differentially expressed miRNAs. Quantitative real-time polymerase chain reaction applied detect levels RNAs, while western blot immunofluorescence...

The prevalence of neurodegenerative diseases has increased in recent decades. Its exact pathogenesis is not yet fully understood, and only a few drugs can be used clinically to alleviate disease symptoms. Increasing evidence highlights plant-derived compounds are becoming promising resource for mitigating the onset progression diseases. Uvaol (

Biotransformation of ursonic acid (1) by two fungal strains Aspergillus ochraceus CGMCC 3.5324 and oryzae 3.407 yielded thirteen new compounds (4, 5, 7-10, 13-19), along with five recognized ones. The structural details were determined through spectroscopic examination (NMR, IR, HR-MS) X-ray crystallography. Various modifications, including hydroxylation, epoxidation, lactonization, oxygen introduction, transmethylation, identified on the ursane core. Additionally, anti-neuroinflammatory...

Two new tigliane diterpenes, named eupneonoids A (1) and B (2), together with four known analogues (3-6) were isolated from the whole plant of Euphorbia neorubella Bruyns. Their structures deduced based on detailed spectroscopic analysis. All isolates displayed cytotoxic effects against A549 human tumor cell lines IC50 values ranging 1.318 to 7.042 μM.

In this study, the biotransformation of asiatic acid by Cunninghamella echinulata CGMCC 3.970 and Circinella muscae 3.2695 was investigated. Scaled-up reactions yielded eight metabolites. Their structures were established based on extensive NMR HR-ESI-MS data analyses four them are new compounds. C. could catalyze regioselecitve hydroxylation, carbonylation lactonization to yield five selectively acetylation glycosylation products. Furthermore, all identified metabolites evaluated for their...

采用乙醇为助磨剂,利用球磨的方法将5-15μm长的多壁碳纳米管切短成长度约为200nm,并且分布较为均匀的短碳纳米管（SCNT）.以SCNT为载体,采用有机溶胶法制得了含铂20%（w）的Pt/SCNT及PtRu/SCNT催化剂.实验发现：对于甲醇的阳极电氧化过程,以切短碳纳米管为载体的Pt/SCNT催化剂具有比相同条件制得的Pt/CNT催化剂高得多的催化活性,前者甲醇氧化峰电流密度是后者的1.4倍,并且远远高于商品的Pt/C催化剂.同时我们发现添加了钌的PtRu/SCNT具有比不含钌的催化剂更好的活性.采用X射线衍射（XRD）、透射电镜（TEM）、比表面积分析（BET）等方法对催化剂进行表征,结果表明,切短碳纳米管的晶相结构并未改变,但Pt/SCNT和PtRu/SCNT催化剂的比表面积和电化学活性得到了显著的提高.