A5103176362- Hormonal Regulation and Hypertension
- Advances in Cucurbitaceae Research
- Plant Disease Resistance and Genetics
- Microbial Metabolites in Food Biotechnology
- Vitamin D Research Studies
- Plant Gene Expression Analysis
- Corneal surgery and disorders
- Genomics and Phylogenetic Studies
- Industrial Gas Emission Control
- Blood Pressure and Hypertension Studies
- Food Quality and Safety Studies
- Gout, Hyperuricemia, Uric Acid
- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Fungal Diseases
- Pharmacological Effects of Natural Compounds
- Corneal Surgery and Treatments
- Healthcare Operations and Scheduling Optimization
- Race, Genetics, and Society
- Photosynthetic Processes and Mechanisms
- Antibiotic Resistance in Bacteria
- Phytochemistry and Bioactive Compounds
- Esophageal Cancer Research and Treatment
- Antimicrobial agents and applications
- Military Defense Systems Analysis
- Seed and Plant Biochemistry
People's Hospital of Xinjiang Uygur Autonomous Region
2024-2025
First Hospital of Xi'an
2021-2023
Xinjiang Medical University
2023
First Affiliated Hospital of Xinjiang Medical University
2023
Changchun University
2022
Shandong Maternal and Child Health Hospital
2022
Shandong Provincial Hospital
2022
Shandong University
2022
People’s Hospital of Wenshan Prefecture
2021
Nanjing Agricultural University
2018-2019
This study sought to investigate the relationship between systemic inflammatory response index (SIRI) and bone mineral density (BMD), osteoporosis, future fracture risk in elderly hypertensive patients.
Prior research has highlighted the association between uric acid (UA) and activation of renin-angiotensin-aldosterone system (RAAS). However, specific relationship aldosterone, RAAS's end product, UA-related diseases remains poorly understood. This study aims to clarify impact aldosterone on development progression hyperuricemia gout in hypertensive patients.
Objective: This study aimed to evaluate the relationship between systemic inflammation response index (SIRI) and risk of stroke its subtypes in elderly patients with hypertension explore predictive accuracy any potential effect modifiers. Methods: The included 4749 participants no history at baseline. Cox regression was used estimate adjusted hazard ratios (HR) 95% confidence intervals (CIs). Interaction tests subgroup analyses were conducted. performance various inflammatory indicators for...
Previous studies have suggested that aldosterone may play a major role in calcium-phosphorus homeostasis and bone metabolism. However, the relationship between plasma concentrations (PAC) mineral density (BMD) middle-aged elderly hypertensive patients remains unclear. Therefore, this study sought to investigate PAC levels BMD explore PAC's potential impact on osteoporosis future fracture risk patients.
Abstract The purpose of this study was to determine the long-term pattern plasma aldosterone concentration (PAC) trajectories and explore relationship between PAC trajectory patterns cardiovascular disease (CVD) risk in patients with hypertension. Participants were surveyed three times 2010 2016, latent mixed modeling employed over exposure period (2010–2016). A Cox regression analysis used examine association CVD (stroke myocardial infarction). Hazard ratios (HRs) corresponding 95%...
Abstract Objective Recently, the stress hyperglycemia ratio (SHR) has been introduced as a metric to signify relative hyperglycemia. This study aimed investigate relationship between SHR and in-hospital mortality length of stay occurring during hospitalization in stroke patients. Methods The retrospective cohort comprised total 4,018 patients diagnosed with acute stroke. is expressed by formula: = ABG (mmol/L) / [1.59 × HbA1c (%) − 2.59]. Outcomes included stay. Multivariable logistic linear...
Objective To explore the link between plasma aldosterone concentration (PAC) and prevalence of metabolic dysfunction-related fatty liver disease (MAFLD) in hypertensive patients. Methods We analyzed data from 41,131 hospitalized patients January 1, 2014, to December 31, 2023. Multivariate logistic regression models tested associations, with threshold, subgroup, sensitivity analyses conducted validate findings. Results For each 5-unit increase PAC, risk MAFLD rose by 1.57 times, consistent...
Abstract Here, we report a high-quality draft genome of Chinese radish ( Raphanus sativus ) cultivar. This contains 387.73 Mb assembled scaffolds, 83.93% the scaffolds were anchored onto nine pseudochromosomes and 95.09% 43 240 protein-coding genes functionally annotated. 184.75 Mb (47.65%) repeat sequences was identified in genome. By comparative analyses against 10 other plant genomes, 2 275 780 gene families found unique to R. . is good reference for genomic study great value genetic...
Since its discovery in Escherichia coli, the emergence and rapid spread of plasmid-mediated colistin resistance gene mcr-1 have become a public health concern. Livestock manure is potentially important reservoir because has been widely used livestock production. Efforts made to accurately quantify prevalence dynamic changes therein during thermophilic composting few far between. In this study, 51 collected samples from four kinds manures was detected quantified. total, 16 were found be...
The objective of this study was to ascertain the relationship between weight-adjusted waist index (WWI) and risk stroke in an elderly hypertensive population, a that has not been previously elucidated. Cox regression model employed assess correlation baseline WWI measurements incidence stroke. To further elucidate shape association stroke, restricted cubic splines were employed. Furthermore, subgroup analyses interaction tests carried out investigate potential heterogeneities. Our cohort...
Background: Previous studies have linked primary aldosteronism to simple renal cysts (SRC), but the relationship between plasma aldosterone concentration (PAC) and SRC remains unclear. This study aimed investigate association PAC in hypertensive patients. Methods: A total of 30,135 patients who visited our hospital from January 2014 December 2023 were included. Logistic regression analyses conducted explore SRC, while restricted cubic splines (RCS) assessed dose-response relationship....
Objectives To investigate the relationship between plasma aldosterone concentration (PAC) and prevalence of peripheral artery disease (PAD) in hypertensive patients to determine any potential threshold effects. Methods This cross-sectional study analyzed data from 13,157 individuals People's Hospital Xinjiang Uygur Autonomous Region, China. PAD was diagnosed based on an ankle-brachial index (ABI) ≤0.90. A multivariate logistic regression model utilized evaluate association PAC PAD, a...
This study aimed to investigate the effects of cumulative exposure plasma aldosterone concentration (PAC) and its time course on chronic kidney disease (CKD) in hypertensive patients, with goal providing insights for preventing future CKD events, especially younger patients. enrolled a total 7142 participants, each whom had undergone at least two PAC measurements before age 60. We calculated annual area under curve (AUC) used Cox regression analyses examine association between PAC_AUC risk....
Objective The objective of this study is to explore whether metagenomic next-generation sequencing (mNGS) and Epithelial Neutrophil Activating Peptide-78 (ENA-78) assays in the amniotic fluid (AF) patients with preterm labor (PTL) could be employed for diagnosing intra-amniotic infection/inflammation (IAI/I) predict outcomes emergency cerclage women cervical insufficiency(CI). Methods AF samples from 40 were subjected PTL mNGS microbial culture diagnose infection known as invasion cavity...
Abstract Background and Aim The body's requirement for iron is different at developmental stages. However, the molecular mechanisms of age‐dependent metabolism are poorly understood. In present study, we investigated expression transport proteins in duodenum S prague– D awley rats five age Methods Male postnatal week ( PNW ) 1, 3, 12, 44, 88 were employed study. Serum status tissue non‐heme concentrations spleen, liver, bone marrow, heart, kidney, duodenal epithelium, gastrocnemius examined...
Purpose: Cardiovascular disease is the leading cause of mortality in patients with type 2 diabetes mellitus (T2DM). This study aimed to develop and validate a nomogram for predicting risk factors coronary heart (CHD) T2DM population northwestern China. Patients Methods: The records 2357 who were treated First Affiliated Hospital Xinjiang Medical University from July 2021 2022 reviewed. After some data (n =239) excluded, 2118 participants included randomly divided into training set =1483)...
Premature birth is a common obstetric complication but its pathogenesis unclear. Inflammation at the maternal-fetal interface in preterm labor leads to infiltration of neutrophils, which promotes inflammatory responses and induces degradation extracellular matrix cell apoptosis, thus contributing labor. It unclear whether neutrophil traps (NETs), functional form are involved labor.After collecting amniotic membranes from research objects, we localized NETs by immunofluorescence evaluated...
Objective: Previously, we demonstrated that aldosterone (ALD) is associated with aortic aneurysm (AA) or dissection (AD). However, the underlying pathological mechanisms for ALD triggering AA AD remain elusive. Furthermore, whether antagonists are potential targeted drugs remains unclear. Design and method: Nine-month-old male C57BL/6J mice received salt 4 weeks AA/AD modeling. The antagonist treatment group spironolactone finerenone by gavage morning after osmotic minipump implantation....