A5100447208- Photosynthetic Processes and Mechanisms
- Plant tissue culture and regeneration
- Lipid metabolism and biosynthesis
- MicroRNA in disease regulation
- Ginseng Biological Effects and Applications
- Nitrogen and Sulfur Effects on Brassica
- RNA Research and Splicing
- Plant biochemistry and biosynthesis
- Plant Gene Expression Analysis
- Phytochemistry and Biological Activities
- Postharvest Quality and Shelf Life Management
- Research in Cotton Cultivation
- Plant Parasitism and Resistance
- Genetic Mapping and Diversity in Plants and Animals
- Plant Molecular Biology Research
- Electrocatalysts for Energy Conversion
- Cancer-related molecular mechanisms research
- Plant nutrient uptake and metabolism
- Advanced battery technologies research
- Seed Germination and Physiology
- FOXO transcription factor regulation
- Venomous Animal Envenomation and Studies
- Bioactive Natural Diterpenoids Research
- Plant responses to water stress
- Chromosomal and Genetic Variations
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2025
Huazhong University of Science and Technology
2019-2024
Huazhong Agricultural University
2024
Shanghai East Hospital
2022-2024
Ministry of Education of the People's Republic of China
2022-2023
East China Normal University
2023
First Affiliated Hospital of Nanchang University
2022
Nanchang University
2022
Affiliated Hospital of Hebei University
2020
Anhui University of Traditional Chinese Medicine
2019
Ten new highly oxidized monomeric (1–8) and dimeric guaianolides (9 10), along with two known guaianolide derivatives (11 12), were isolated from the aerial parts of Chrysanthemum indicum using a bioassay-guided fractionation procedure. The compounds characterized by basic analysis spectroscopic data obtained, absolute configurations determined both empirical approaches ECD calculations. Inhibitory effects 1–12 on nitric oxide production investigated in lipopolysaccaride (LPS)-mediated RAW...
Abstract Panax ginseng , a perennial herbaceous plant and representative of the genus, is renowned for its exceptional medicinal value economic benefits, often referred to as “King Herbs.” With increasing market demand limited availability suitable cultivation land, issue continuous cropping obstacles P. has become increasingly prominent, directly hindering sustainable development industry. This article summarizes concept hazards and, drawing on latest research, provides an in-depth analysis...
Sinopodophyllum hexandrum (Royle) Ying, the only species of in Berberidaceae, is an endangered traditional Tibetan medicine. The harsh plateau growth environment makes S. tough to breed and meet global demand for clinical medications such as podophyllotoxin (PTOX) etoposide. Jasmonic acid (JA) acknowledged a key phytohormone that modulates stress responses by activating defense mechanisms promoting production specialized metabolites, which offers valuable insights developing varieties are...
Osteosarcoma is one of the most malignant bone tumors, and its major threats are aggressive invasion early tumor metastasis, which result in a poor prognosis high mortality. Accumulating evidence indicates that ginsenoside compound K (CK) has significant antitumor effect, particularly on inhibition proliferation numerous human tumors. In present study, it was revealed CK inhibited viability osteosarcoma cells. Moreover, demonstrated induced apoptosis migration cells via apoptotic staining,...
Brassica napus is an important oilseed crop that offers a considerable amount of biomass for global vegetable oil production. The establishment efficient genetic transformation system with convenient transgenic-positive screening method great importance gene functional analysis and molecular breeding. However, to our knowledge, there are few the aforementioned systems available application in B. napus.Based on well-established napus, five vectors carrying red fluorescence protein encoding...
Heme is a crucial component in endowing plant-based meat analogs with flavor and color. This study aimed to develop green strategy for heme production by reducing fermentation off-odor accelerating synthesis. First, an efficient CRISPR/Cas9n system was constructed
Ginseng, the root and rhizome of
Roots of Euphorbia fischeriana and ebracteolata are recorded as the source plant traditional Chinese medicine “Langdu,” containing active ingredients with anticancer anti-AIDS activity. However, two species have specific patterns in graphic distribution. Compared E. ehracteolata, distributes higher latitude lower temperature areas might experienced cold stress adaptation. To reveal molecular mechanism environmental adaptation, RNA-seq was performed toward roots, stems, leaves ehracteolata ....
Noncoding RNAs (ncRNAs) play important roles in cancer biology, providing potential targets for intervention. As a new class of endogenous noncoding RNAs, circular (circRNAs) have been recently identified cell development and function, certain types pathological responses contribute to progression, including glioblastoma. However, the mechanisms underlying relationship between circRNAs glioblastoma progression are still largely unknown. Methods: The expression RNA 0010117 (circ-0010117) were...
Rapeseed (Brassica napus) supplies about half of the vegetable oil in China. Increasing production and searching for genes that control content crop are research goals. In our previous studies, four major QTL located on A08, A09, C03 C06 KenC-8 × N53-2 (KN DH) mapping population were detected. The parental lines resequenced to identify structural variations candidate affecting these regions. Insertion-deletion (InDel) markers developed used narrow Differentially expressed regions...
Brassica napus is the most important oilseed crop in world, and lipid was stored oil body (OB) form of triacylglycerol. At present, studies on relationship between morphology seed content B. focused mature seeds. In present study, OBs different developing seeds with relatively high (HOC) about 50% low (LOC) 39% were analyzed. It revealed that size first increased then decreased both materials. And late developmental stages, average OB rapeseed HOC higher than LOC, while it reversed early...
Fatty acid desaturases add a second bond into single of carbon atoms in fatty chains, resulting an unsaturated between the two carbons. They are classified soluble and membrane-bound desaturases, according to their structure, subcellular location, function. The orthologous genes Camelina sativa were identified analyzed, total 62 desaturase identified. It was revealed that they had common domain, which has evolved separately, proteins same family also originated from ancestry. A mix...
As a high-value active component in <italic>Salvia miltiorrhiza</italic> (Danshen), the accumulation of tanshinones is under influence various environmental factors, yet it unknown whether light, as an essential factor for plant growth, regulates biosynthesis tanshinones. In this study, we first measured temporal jasmonates (JAs) and dark-to-light transition, found that JA, JA-Ile light-dependent. Transcriptome analysis revealed <italic>SmAOS</italic> <italic>SmAOC</italic> involved JA...
SUMMARY Very long‐chain fatty acids (VLCFAs) are important industrial raw materials and can be produced by genetically modified oil plants. For a long time, class A lysophosphatidic acid acyltransferase (LPAT) was considered unable to promote the accumulation of VLCFA in crops. The bottlenecks that transgenic high lines have an content penalty low amount phosphatidylcholine remains intractable. In present study, LPAT2 from Camelina sativa (CsaLPAT2) promoting VLCFAs phospholipid found....
Despite the critical role of bacterial cell walls in maintaining shapes, certain environmental stressors can induce transition many species into a wall-deficient state called L-form. Long-term induced Escherichia coli L-forms lose their rod shape and usually hold significant mutations that affect division growth. Besides this, genetic background L-form bacteria is still poorly understood. In present study, genomes two stable strains E. (NC-7 LWF+) were sequenced gene mutation status was...
To obtained an accurate, rapid and efficient method for authenticate medicinal snakes listed in Chinese Pharmacopoeia (Zaocysd humnades, Bungarus multicinctus, Agkistrodon acutus), a PCR its adulterants was established based on the classic molecular authentication methods. DNA extracted by alkaline lysis specific primers were amplified two-steps amplification method. The denatured annealing temperature cycle numbers optimized. When 100 x SYBR Green I added product, strong green fluorescence...
In this study, a novel strain for degrading chitin was identified as Bacillus paralicheniformis HL37, and the key chitinase CH1 firstly mined through recombinant expression in amyloliquefaciens HZ12. Subsequently, sequence composition catalytic mechanism of protein were analyzed. The molecular docking indicated that triplet Asp526, Asp528, Glu530 active center. enzymatic properties analysis revealed optimal reaction temperature pH 65 °C 6.0, respectively. Especially, activity showed no...