A5000776117- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Pulmonary Hypertension Research and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Issues in Pregnancy
- Coronary Artery Anomalies
- Cardiovascular Disease and Adiposity
- Infective Endocarditis Diagnosis and Management
- Mechanical Circulatory Support Devices
- Kawasaki Disease and Coronary Complications
- Elasticity and Material Modeling
- Cardiomyopathy and Myosin Studies
- Transplantation: Methods and Outcomes
- Protein Structure and Dynamics
- Cardiac Ischemia and Reperfusion
- Radiomics and Machine Learning in Medical Imaging
- Advanced MRI Techniques and Applications
- Nuclear Structure and Function
- Cardiovascular Health and Disease Prevention
- RNA Research and Splicing
Boston Children's Hospital
2016-2025
Harvard University
2016-2025
Children's Hospital of Philadelphia
2024
Boston Children's Museum
2007-2023
Baylor College of Medicine
2022
Texas Children's Hospital
2022
Brown University
2018
Jackson Memorial Hospital
2015
Harvard University Press
2013
Children's Hospital
2009-2012
Background— Pulmonary valve replacement (PVR) in repaired tetralogy of Fallot (TOF) reduces pulmonary regurgitation and decreases right ventricular (RV) dilation, but its long-term impact on tachycardia (VT) mortality is unknown. This study aimed to determine the incidence death VT TOF after PVR test hypothesis that leads improvement these outcomes. Methods Results— A total 98 patients with late for RV dilation were identified. Matched control subjects identified 77 patients; had no PVR....
Cardiac manifestations in multisystem inflammatory syndrome children (MIS-C) occur ∼80% of patients. Left ventricular (LV) systolic dysfunction is the most frequent cardiac finding.In this single-centre, retrospective cohort study, we report on detailed assessment LV function MIS-C patients using strain and rate analysis. We compare those with normal peak z-scores (both longitudinal circumferential strain) to abnormal (decreased and/or strain).Among 25 patients, 14 (56%) were male, 20 (80%)...
Background: Right ventricular (RV) morphology has been associated with adverse clinical outcomes in Fontan patients. The impact of RV versus left on stress and strain single ventricles is not well known. Methods Results: Cardiac magnetic resonance examinations 193 patients the circulation were retrospectively analyzed. Ventricular mass, volume, global circumferential longitudinal strain, average end-systolic fiber calculated using previously published methods. Compared morphology, (48%) was...
In addition to tricuspid regurgitation (TR) and right ventricular (RV) enlargement, patients with Ebstein anomaly are at risk for left (LV) dysfunction dyssynchrony. We studied the impact of cone valve reconstruction operation on LV size, function, All who had both pre- postoperative cardiovascular magnetic resonance (CMR) studies were retrospectively identified. From cine images, RV volumes ejection fractions (EF) calculated, circumferential longitudinal strain measured by feature tracking....
In patients with repaired tetralogy of Fallot (TOF), a better understanding the impact surgical pulmonary valve replacement (PVR) on ventricular mechanics may lead to improved indications and outcomes. Therefore, we used cardiovascular magnetic resonance (CMR) feature tracking analysis quantify strain synchrony in TOF before after PVR.
Transcatheter pulmonary valve (TPV) replacement is an emerging therapy intended to restore function in patients with right ventricular outflow tract conduit dysfunction; the impact of this technique on strain and synchrony not known.Cardiac magnetic resonance ECG data acquired at 1 center as part US Melody TPV trial were analyzed. Biventricular mechanical measurements made based short-axis 4-chamber steady-state free precession images using feature tracking software. Post- versus pre-TPV...
The impact of prenatal intervention on fetal cardiac function has not been well defined. We assessed standard ventricular parameters and strain in fetuses with evolving hypoplastic left heart syndrome (HLHS) treated aortic valvuloplasty (fAVP).Fetuses valvar stenosis that underwent fAVP were studied. Echocardiographic images prior to (Pre), within 1 week after (Post), at the last follow-up examination (FU) analyzed. Left (LV) circumferential (LVCS) longitudinal (LVLS), right (RV) (RVLS), LV...