- Antibiotic Resistance in Bacteria
- Pneumocystis jirovecii pneumonia detection and treatment
- Vibrio bacteria research studies
- Antibiotics Pharmacokinetics and Efficacy
- Autophagy in Disease and Therapy
Jinan University
2022-2023
Southern University of Science and Technology
2022-2023
Shenzhen Second People's Hospital
2022
Adaptation to selective pressures is crucial for clinically important pathogens establish epidemics, but the underlying evolutionary drivers remain poorly understood. The current epidemic of carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat public health. In this study we analyzed genome sequences 794 CRKP bloodstream isolates collected in 40 hospitals China between 2014 and 2019. We uncovered subclonal replacement predominant clone ST11, where previously prevalent...