A5103169095- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
- Biochemical and Structural Characterization
- Urinary Tract Infections Management
- Microbial Metabolism and Applications
- Healthcare and Venom Research
- MicroRNA in disease regulation
- Infections and bacterial resistance
- Cancer Research and Treatments
- Bacteriophages and microbial interactions
- Circular RNAs in diseases
- Plant Pathogenic Bacteria Studies
- Cancer-related gene regulation
- Venomous Animal Envenomation and Studies
- Nicotinic Acetylcholine Receptors Study
- Leech Biology and Applications
- Hemodynamic Monitoring and Therapy
- Liver Disease Diagnosis and Treatment
- Neuroscience and Neuropharmacology Research
- Extracellular vesicles in disease
- Muscle metabolism and nutrition
- Bacterial biofilms and quorum sensing
Second Affiliated Hospital of Guangzhou Medical University
2024
Guangzhou Medical University
2024
The First People’s Hospital of Lianyungang
2018-2023
Taizhou First People's Hospital
2021
Yichun University
2010-2017
Zhaotong University
2006
Adaptation to selective pressures is crucial for clinically important pathogens establish epidemics, but the underlying evolutionary drivers remain poorly understood. The current epidemic of carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a significant threat public health. In this study we analyzed genome sequences 794 CRKP bloodstream isolates collected in 40 hospitals China between 2014 and 2019. We uncovered subclonal replacement predominant clone ST11, where previously prevalent...
In this first national bloodstream infection (BSI) surveillance program in China, we assessed the composition of pathogenic bacteria and trends for antimicrobial susceptibility over a 6-year period China.Blood bacterial isolates from patients at hospitals participating Blood Bacterial Resistant Investigation Collaborative System (BRICS) were collected January 2014 to December 2019. Only isolate species per patient was eligible full study period. Antibiotic-susceptibility testing conducted by...
We recently reported the complete sequence of a blaKPC-2- and rmtB-carrying IncFII-family plasmid p675920-1 with pKPC-LK30/pHN7A8 hybrid structure. Comparative genomics additional sequenced plasmids similar structures their prevalence in blaKPC-carrying Klebsiella pneumoniae strains from China were investigated this follow-up study.A total 51 K. isolated 2012 to 2016 five Chinese hospitals genotyped by multilocus typing. The four representative compared pCT-KPC. Plasmid transfer,...
A pathophysiological feature of septic organ failure is endothelial dysfunction in sepsis (EDS). The physiological and pathological mechanism considered to be vascular leakage caused by dysfunction. These changes lead systemic injury. However, an analysis using bibliometric methods has not yet been conducted the field EDS. This study was provide overview knowledge structure research trends
Extrahepatic metastatic hepatocellular carcinoma (HCC) and its insensitivity to chemotherapy are the main causes of poor prognosis in patients with HCC. This study investigated anti-cancer effect Macrothele raveni venom on intrarenal HCC.Subrenal capsule xenograft model HCC was established by inoculation H22 liver cancer cells.The general health, histology, molecular changes were observed after administering 10 times different dose raven injections. A volume 0.8 μg/ml 1.0 significantly...
// Jiao Feng 1, * , Zhe Yin Zhan 1 Haifeng Mao 2 Xiaoyuan Jiang Lijun Zeng Wenhui Yang Huiying Jinglin Wang Haijian Zhou 3, 4 and Dongsheng State Key Laboratory of Pathogen Biosecurity, Beijing Institute Microbiology Epidemiology, Beijing, 100071, China The First People’s Hospital Lianyungang, 222002, 3 for Infectious Disease Prevention Control, National Communicable Control Prevention, Chinese Center 102206, Collaborative Innovation Diagnosis Treatment Diseases, Hangzhou, 310003,...
Objective To investigate the distribution and antimicrobial resistance profile of clinical bacteria isolated from blood culture in China. Methods The bacterial strains member hospitals Blood Bacterial Resistant Investigation Collaborative System (BRICS) were collected during January 2016 to December 2017. Antibiotic susceptibility tests conducted by agar dilution or broth methods recommended US Clinical Laboratory Standards Institute (CLSI) 2019. WHONET 5.6 was used analyze...
Objective To investigate the regulatory networks of DNA methylation profiles in STEMI by microarrays. Methods A total often male patients with and ten healthy controls were recruited. Methyl-DNA immunoprecipitation Nimblegen HG18 Meth 385K promoter plus CpG island microarrays used to identify differentially methylated regions. And several bioinformatics analysis tools which included chromosomal assignment, gene ontology pathway SignalMap The Database for Annotation, Visualization...
Abstract Background: Multidrug-resistant (MDR) bloodstream infection (BSI) by Gram-negative bacteria (GNB) is an important cause of mortality in the intensive care unit (ICU). The purpose this study was to compare clinical characteristics some GNB BSIs and analyze their drug resistance, with emphasis on analysis prognostic risk factors related MDR-Acinetobacter baumannii (A. baumannii) BSI.Methods: A retrospective conducted ICU lianyungang hospital China. Patients due MDR-A. baumannii,...