A5101915490- Power Systems and Renewable Energy
- Nanoparticle-Based Drug Delivery
- Plant Physiology and Cultivation Studies
- Power Systems and Technologies
- Nanoplatforms for cancer theranostics
- Postharvest Quality and Shelf Life Management
- Smart Grid and Power Systems
- Acute Myeloid Leukemia Research
- Pancreatic and Hepatic Oncology Research
- High-Voltage Power Transmission Systems
- Injury Epidemiology and Prevention
- Evaluation Methods in Various Fields
- Hemoglobinopathies and Related Disorders
- Pancreatitis Pathology and Treatment
- Plant Surface Properties and Treatments
- Traffic and Road Safety
- Natural Compounds in Disease Treatment
- Simulation and Modeling Applications
- Evaluation and Optimization Models
- Cancer, Hypoxia, and Metabolism
- Adventure Sports and Sensation Seeking
- Head and Neck Anomalies
- Engineering Structural Analysis Methods
- Supramolecular Self-Assembly in Materials
- Calcium signaling and nucleotide metabolism
Southwest University
2023-2025
Jiangsu University
2023
Guangxi Medical University
2023
First Affiliated Hospital of Bengbu Medical College
2023
State Grid Corporation of China (China)
2023
Nanchang University
2022
Sichuan University
2017-2022
Zhongshan Hospital
2022
Fudan University
2022
China Geological Survey
2015
Mesangial cells-mediated glomerulonephritis is a frequent cause of end-stage renal disease. Here, we show that celastrol effective in treating both reversible and irreversible mesangioproliferative rat models, but find its off-target distributions severe systemic toxicity. We thus target to mesangial cells using albumin nanoparticles. Celastrol-albumin nanoparticles crosses fenestrated endothelium accumulates cells, alleviating proteinuria, inflammation, glomerular hypercellularity,...
Due to the critical correlation between inflammation and carcinogenesis, a therapeutic candidate with anti-inflammatory activity may find application in cancer therapy. Here, we report efficacy of celastrol as promising compound for treatment pancreatic carcinoma via naïve neutrophil membrane-coated poly(ethylene glycol) methyl ether-block-poly(lactic-co-glycolic acid) (PEG-PLGA) nanoparticles. Neutrophil nanoparticles (NNPs) are well demonstrated overcome blood pancreas barrier achieve...
Background While previous studies have investigated the risk factors contributing to drowning risk-taking behaviours in adolescents, whether peer influence this relationship remains uncertain. This study explored potential between and adolescent while examining perceptions play a moderating role relationship. Methods A national survey of 7485 adolescents China was conducted using three scales: Drowning Risk-Taking Behaviours scale, Peer scale Risk Perceptions scale. Pearson’s analysis...
Chronic myeloid leukemia (CML) is a myeloproliferative disorder that can progress to an accelerated or blast phase if left untreated inadequately managed. Acute transformation of CML, particularly into mixed lineage leukemia, rare and challenging complication. This case report describes the clinical course 30-year-old male patient with CML progressing acute complicated by gastrointestinal bleeding. The patient, initially diagnosed in June 2019, was treated imatinib. However, after...
The present study proposes an algorithm to extract obscured traffic sign information from road driving images and fuse it with the vehicle movement process by integrating speed. Given low recognition rate of signs, proposed utilizes a traditional color-shape approach potential regions. fusion multiple consecutive frames into single frame enhances completeness accuracy information, bringing closer original characteristics sign. experimental results demonstrate that fusing first third improves...
SummaryThe structure and mechanical properties (e.g. strength extensibility) of the pericarp, cuticle layer, fruit desiccation rate were compared in two litchi (Litchi chinensis Sonn.) cultivars, cracking-resistant cv. ‘Huaizhi’ cracking-susceptible ‘Nuomici’. Pericarp extensibility higher than ‘Nuomici’ prior to rapid aril expansion. Based on changes pericarp structure, we propose a “Zig-zag Unfolding” model for extension driven by expanding aril. In this model, cristate spongy tissue...
Acute pancreatitis (AP) is a sudden inflammation of the pancreas with high mortality rate worldwide. As severe complication to AP, acute lung injury has been major cause death among patients AP. Poor penetration across blood barrier (BPB) and insufficient drug accumulation at target site often result in poor therapeutic outcome. Our previous work successfully demonstrated dual-specific targeting strategy using phenolic propanediamine moiety. Inspired by this, simplified ligand structure,...
The association between white blood cells (WBCs) and metabolic syndrome (MS) has been consistently reported in previous studies using regional samples. However, it remains unclear whether this relationship urban-rural differences is independent of insulin resistance a large-scale representative sample. Additionally, accurate risk prediction patients with MS crucial for developing targeted interventions to enhance the quality life prognosis patients.The aims study were (1) examine...
Introduction Although previous research has examined the risk factors for drowning behavior among adolescents, it is unclear whether this association influenced by water safety knowledge. This study aimed to examine knowledge associated with adolescents’ behaviors and perceptions attitudes could have a chain mediating role in between behaviors. Methods included 7,485 adolescents from five Chinese provinces cities. We used Drowning Risk Behaviors Scales (DRBS) evaluate of The Water Safety...
Pancreatic carcinoma elevates quickly and thus has a high mortality rate. Therefore, early treatment is essential for treating pancreatic carcinoma. KRAS the most frequently identified one of earliest mutations in tumorigenesis. Thus, KRAS-mutant cell an ideal target carcinoma, especially at stage. mutation increases macropinocytosis cancer cells, enhancing internalization exosomes. Because acquiring natural exosomes could be laborious their encapsulation efficiency often unsatisfactory, we...
A good photosensitizer (PS) delivery system could enhance the efficiency and reduce side effects of anti-tumor photodynamic therapy (PDT) by improving accumulation in tumor, uptake tumor cells, intracellular release PS. Thus, we rationally developed a multi-stimulus-responsive PS nanocarrier with double-layered core-shell structure: mPEG-azo-hyaluronic acid-sulfide-Ce6 (PaHAsC). In PaHAsC, mPEG coat provides protection before entering hypoxic microenvironment, where leaves to expose HA...
Abstract Background According to the Global Report on Drowning: Preventing a Leading Killer and Drowning : An Implementation Guide , two documents released by World Health Organization in 2014 2017, respectively, 372,000 people drown each year globally (approximately 42 per hour), half of whom are below 25 years old. Chinese adolescents aged 18–24 main victim group. Intermediate swimming college students more susceptible risk‐taking behavior drowning while swimming. In particular, with...
Introduction: Pancreatic cancer, or pancreatic duct adenocarcinoma (PDAC), remains one of the most lethal cancers and features insidious onset, highly aggressive behavior early distant metastasis. The dense fibrotic stroma surrounding tumor cells is thought to be a shield resist permeation chemotherapy drugs in treatment PDAC. Thus, we synthesized pancreas-targeting paclitaxel-loaded PEGylated liposome investigated its antitumor efficacy patient-derived orthotopic xenograft (PDOX) nude mouse...
Mobile phone dependence (also known as internet dependence, MPD), defined a problematic behavior characterized by excessive use or intermittent craving to mobile phone, results in various social, behavioral, and affective problems daily life. In sports, MPD is directly related the physical mental health sports performance of athletes. The individual environmental factors, neurobiological mechanisms theoretical models affecting athletic were analyzed reviewing previous studies, aiming...