A5103151659- Ubiquitin and proteasome pathways
- Peptidase Inhibition and Analysis
- Cancer-related molecular mechanisms research
- Cancer-related Molecular Pathways
- Circular RNAs in diseases
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Lung Cancer Research Studies
- MicroRNA in disease regulation
- Cancer-related gene regulation
- GDF15 and Related Biomarkers
- Intensive Care Unit Cognitive Disorders
- Medical Imaging and Pathology Studies
- Ferroptosis and cancer prognosis
- Tissue Engineering and Regenerative Medicine
- Gastroesophageal reflux and treatments
- Genetics and Neurodevelopmental Disorders
- Nuclear Receptors and Signaling
- Metal-Organic Frameworks: Synthesis and Applications
- Endoplasmic Reticulum Stress and Disease
- Chromium effects and bioremediation
- Anesthesia and Sedative Agents
- Neuroendocrine Tumor Research Advances
- Mesenchymal stem cell research
- Cancer Mechanisms and Therapy
Second Hospital of Shandong University
2023-2024
Nanchang University
2020-2024
Second Affiliated Hospital of Nanchang University
2020-2024
Yulin Orthopedics Hospital of Chinese and Western Medicine
2021-2022
Shangluo Central Hospital
2022
Southern Medical University
2013
First Affiliated Hospital of Nanchang University
2010
Abstract Lacking effective therapeutic targets heavily restricts the improvement of clinical prognosis for patients diagnosed with esophageal squamous cell carcinoma (ESCC). Ubiquitin Specific Peptidase 21 (USP21) is dysregulated in plenty human cancers, however, its potential function and relevant molecular mechanisms ESCC malignant progression as well value translation remain largely unknown. Here, vitro vivo experiments revealed that aberrant upregulation USP21 accelerated proliferation...
Abstract Paclitaxel resistance is associated with a poor prognosis in non-small cell lung cancer (NSCLC) patients, and currently, there no promising drug for paclitaxel resistance. In this study, we investigated the molecular mechanisms underlying chemoresistance human NSCLC-derived lines. We constructed paclitaxel-resistant NSCLC lines (A549/PR H460/PR) by long-term exposure to paclitaxel. found that triptolide, diterpenoid epoxide isolated from Chinese medicinal herb Tripterygium wilfordii...
Abstract Background To present an unusual case of abnormal LCA expression and CD43 in SCLC to review the reported literature avoid potential diagnostic pitfalls. Case presentation A 73-year-old male patient suffered from persistent back pain for more than one month. MRI revealed a compression fracture L1-L5 vertebra. CT scan multiple nodules masses at left root neck, lung hilum mediastinum, areas bony destruction ribs. Histology tumor that small round cells were arranged nests with necrosis....
Endometriosis is a common benign gynecological disease that causes dysmenorrhea in women of childbearing age. Malignant tumors derived from endometriosis are rarely reported and found only 1% all patients with endometriosis. Here, we report well-differentiated squamous cell carcinoma (SCC) caused by metaplasia co-occurred the uterus ovaries.A 57-year-old postmenopausal woman had 6-month history irregular uterine bleeding. The adnexa were examined computed tomography, there two solid cystic...
Most endoscopists routinely perform moderate or deep sedation for esophagogastroduodenoscopy (EGD). Considering that there is no consensus on the optimal depth and it varies from country to country, our study aims compare effectiveness, cost safety of these two methods in Chinese population.This quasi-experimental included a total 556 eligible patients July 2020 June 2021, they entered group based their choices. Baseline information, scores Patient Satisfaction with Sedation Instrument...
Abstract In the present work, two novel coordination polymers on basis of Cu(II) are hydrothermally produced via utilizing 2,5‐dichloroterephthalic acid (H 2 DCTP), a halogenated linear ligand with existence diverse flexible nitrogen‐donor ligands 1,4‐bis(5,6‐dimethylbenzimidazol‐1‐yl)‐2‐butylene (L2) and 1,1′‐(1,4‐butanediyl)bis‐1 H ‐benzimidazole (L1), their chemical formulae [Cu(L1)(DCTP)] n ( 1 ) [Cu(L2)(DCTP)] ). The evaluation compounds’ treatment effect against thyroid cancer was...