A5107467070- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Mesenchymal stem cell research
- Tissue Engineering and Regenerative Medicine
- RNA modifications and cancer
- Medical and Biological Ozone Research
- Head and Neck Cancer Studies
- Nail Diseases and Treatments
- Cancer Genomics and Diagnostics
- Polysaccharides and Plant Cell Walls
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Inflammatory mediators and NSAID effects
- Vascular Malformations and Hemangiomas
- Endometrial and Cervical Cancer Treatments
- Lung Cancer Treatments and Mutations
- Receptor Mechanisms and Signaling
- Oral and Maxillofacial Pathology
- Animal Virus Infections Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Neuropeptides and Animal Physiology
- Energy Efficient Wireless Sensor Networks
- Cooperative Communication and Network Coding
- Cutaneous lymphoproliferative disorders research
- Carbohydrate Chemistry and Synthesis
University of Macau
2023-2024
Tsinghua University
2024
Yiwu Science and Technology Research Institute
2024
Charité - Universitätsmedizin Berlin
2023
Shanghai University of Sport
2023
Affiliated Hospital of Qingdao University
2023
Tianjin Medical University General Hospital
2023
Tongji Hospital
2016-2023
Guangzhou University of Chinese Medicine
2023
Qingdao University
2023
Candida glabrata is the second most common pathogen of severe candidiasis in immunocompromised hosts, following C. albicans. Although and albicans belong to same genus, they are phylogenetically distinct. C-type lectin receptors (CLRs), acting as pattern-recognition (PRRs), play critical roles host defense against infections. However, our understanding specific CLRs limited. Here, we explored potential lectins Dectin-1 Dectin-2 glabrata. We found that both Dectin-1-deficient mice...
The cell wall is a dynamic structure that important for the pathogenicity of Candida albicans. Mannan, which located in outermost layer wall, has been shown to contribute pathogenesis C. albicans, however, molecular mechanism by this occurs remains unclear. Here we identified novel α-1,6-mannosyltransferase encoded MNN10 We found Mnn10 required α-1,6-mannose backbone biosynthesis and polysaccharides organization. Deletion resulted significant attenuation albicans murine systemic candidiasis...
Prostaglandin D2 receptor 2 (DP2) is an important anti-inflammatory and antiallergic drug target. While inactive DP2 structures are known, its activation mechanisms biased signaling remain unclear. Here, we report cryo-EM of apo DP2–Gi complex, a complex bound to the endogenous ligand D (PGD ), indomethacin, arrestin-biased ligand, at resolutions 2.5 Å, 2.8Å, 2.3 respectively. These reveal distinct binding pose PGD indomethacin provide key insights into transducer coupling. Combining...
Laparoscopic surgery for cervical cancer has the advantages of little blood loss and rapid recovery, but its therapeutic effect is still controversial. This study aims to analyze surgical procedure clinical efficacy tumor-free laparoscopic radical hysterectomy without a uterine manipulator early-stage cancer, explore indications cancer.
Abstract BACKGROUND AND AIMS Calciphylaxis is a rare disease characterized histologically by microvessel calcification and microthrombosis, with high mortality no proven therapy. Here, we reported multidisciplinary regenerative treatment for rescuing severe uremic calciphylaxis patient human amnion-derived mesenchymal stem cells (hAMSCs). METHOD A 34-year-old woman presented progressive skin ischaemia, large areas of painful malodorous ulcers mummified legs. The was diagnosed as based on...