Jian Huang

ORCID: 0009-0003-4220-4474
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About
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Research Areas
  • Ziziphus Jujuba Studies and Applications
  • Plant Virus Research Studies
  • Ginseng Biological Effects and Applications
  • Genetic factors in colorectal cancer
  • Genetic Mapping and Diversity in Plants and Animals
  • Poxvirus research and outbreaks
  • Cancer Cells and Metastasis
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Plant Molecular Biology Research
  • Lung Cancer Treatments and Mutations
  • 3D Surveying and Cultural Heritage
  • Plant Reproductive Biology
  • Plant Physiology and Cultivation Studies
  • Migration, Aging, and Tourism Studies
  • Bacillus and Francisella bacterial research
  • Remote Sensing and LiDAR Applications
  • Ferroptosis and cancer prognosis
  • Robotics and Sensor-Based Localization
  • Obesity, Physical Activity, Diet
  • Physical Activity and Health
  • Cytokine Signaling Pathways and Interactions
  • PI3K/AKT/mTOR signaling in cancer
  • Intergenerational Family Dynamics and Caregiving
  • FOXO transcription factor regulation

First Affiliated Hospital of Kunming Medical University
2021-2024

Kunming Medical University
2021-2024

Connecticut Department of Public Health
2022-2023

Northwest A&F University
2014-2020

Guangdong Medical College
2020

University of Colorado Health
2003

Jujube (Ziziphus jujuba Mill.) belongs to the Rhamnaceae family and is a popular fruit tree species with immense economic nutritional value. Here, we report draft genome of dry jujube cultivar 'Junzao' resequencing 31 geographically diverse accessions cultivated wild jujubes var. spinosa). Comparative analysis revealed that 'Dongzao', fresh jujube, was ~86.5 Mb larger than 'Junzao', partially due recent insertions transposable elements in 'Dongzao' genome. We constructed eight...

10.1371/journal.pgen.1006433 article EN cc-by PLoS Genetics 2016-12-22

The 2022 multicountry mpox outbreak concurrent with the ongoing Coronavirus Disease 2019 (COVID-19) pandemic further highlighted need for genomic surveillance and rapid pathogen whole-genome sequencing. While metagenomic sequencing approaches have been used to sequence many of early infections, these methods are resource intensive require samples high viral DNA concentrations. Given atypical clinical presentation cases associated uncertainty regarding load across both course infection...

10.1371/journal.pbio.3002151 article EN cc-by PLoS Biology 2023-06-13

Background Metabolic syndrome is prevalent worldwide and its prevalence related to physical activity, race, lifestyle. Little data available for people living in rural areas of China. In this study we examined associations activity sedentary behaviors with metabolic components among Methods The Nantong Syndrome Study recruited 13,505 female 6,997 male participants between 2007 2008. Data socio-demographic characteristics lifestyle were collected. analyzed. Results Prevalence was 21.6%. It...

10.1371/journal.pone.0147062 article EN cc-by PLoS ONE 2016-01-20

Background DNA damage repair (DDR) genes were recently implicated in the anti-tumor immune response. Therefore, it is worthwhile to unravel implications of DDR pathways shaping responsiveness colorectal cancer (CRC) patients receiving checkpoint inhibitors (ICI). Methods We analyzed publicly available genomic data from a cohort treated with ICI Memorial Sloan Kettering Cancer Center (MSK cohort). To characterize impact mutation, The Genome Atlas (TCGA) adenocarcinoma (COADREAD) dataset was...

10.3389/fonc.2020.549777 article EN cc-by Frontiers in Oncology 2021-02-19

Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are considered to be more effective than chemotherapy in the treatment of EGFR-mutant advanced non-small cell lung cancer (NSCLC). However, addition EGFR-sensitive mutations, genetic factors that affect prognosis patients who receive TKI not yet clear.The clinical data 36 NSCLC with EGFR mutation received were retrospectively analyzed. Liquid re-biopsy next generation sequencing (NGS) analysis was performed analyze...

10.21037/tlcr-20-679 article EN Translational Lung Cancer Research 2020-08-01

Abstract The 2022 multi-country monkeypox (mpox) outbreak concurrent with the ongoing COVID-19 pandemic has further highlighted need for genomic surveillance and rapid pathogen whole genome sequencing. While metagenomic sequencing approaches have been used to sequence many of early mpox infections, these methods are resource intensive require samples high viral DNA concentrations. Given atypical clinical presentation cases associated uncertainty regarding load across both course infection...

10.1101/2022.10.14.22280783 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2022-10-17

Rationale: Multiple primary cancer is common in clinical practice, but its diagnosis process complicated, and relevant genetic testing required to assist when necessary. The formulation of treatment strategies for multiple a highly personalized process. In this article, we introduce case patient with rectal gastric who was diagnosed cancers, investigate explore the application value next-generation sequencing (NGS) patients colorectal cancers. Patient concerns: A 74-year-old male had mass at...

10.1097/md.0000000000040699 article EN cc-by-nc Medicine 2024-11-29

Sour jujube (Ziziphus jujuba var. spinosa) is an important wild fruit tree and traditional Chinese medicine. Ten microsatellite markers of sour were developed using a modified dual-suppression-PCR technique. Polymorphism each locus was detected in 40 individuals from three natural populations. The number alleles per ranged 2 to 10, with average 6.4. expected observed heterozygosities 0.420 0.832 0.161 0.975, respectively.The will be useful for future genetic diversity population studies, may...

10.5958/j.0975-6906.73.3.052 article EN Indian Journal of Genetics and Plant Breeding (The) 2013-01-01

The rapid increase in the number of disabled elders and great economic social changes call for a synchronised development long-term care services. aim this study was to identify factors determining preference future living arrangements, forecasting demand services.A cross-sectional survey conducted Kunshan between June July 2018. stratified sampling method used survey. multinomial logistic regression model explore influencing factors.The most preferred arrangement live at home. Individual...

10.1111/psyg.12817 article EN Psychogeriatrics 2022-02-21

In order to supply genetic information of Juniperus saltuaria, we reported the complete chloroplast genome sequence based on high-throughput sequencing data. The whole was 128,099 bp long with an asymmetric base composition (32.9% A, 16.9% C, 18.1% G and 32.1% T). annotation predicted a total 116 genes, including 82 protein-coding 30 tRNA 4 rRNA genes. neighbor-joining phylogenetic analysis 45 sequences showed that J. saltuaria more closely related congeneric recurva. assembled will provide...

10.1080/23802359.2020.1781559 article EN cc-by Mitochondrial DNA Part B 2020-06-24
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