A5011763204- Marine Invertebrate Physiology and Ecology
- Coral and Marine Ecosystems Studies
- Immunotherapy and Immune Responses
- Marine Ecology and Invasive Species
- Immune Response and Inflammation
- vaccines and immunoinformatics approaches
- Viral gastroenteritis research and epidemiology
- Monoclonal and Polyclonal Antibodies Research
- Ectopic Pregnancy Diagnosis and Management
- Protist diversity and phylogeny
- Reproductive System and Pregnancy
- Marine Toxins and Detection Methods
- T-cell and B-cell Immunology
- Cutaneous Melanoma Detection and Management
- Marine Biology and Ecology Research
- Virus-based gene therapy research
- Marine Biology and Environmental Chemistry
- Sphingolipid Metabolism and Signaling
- Liver physiology and pathology
- Marine Sponges and Natural Products
- Granular flow and fluidized beds
- Pregnancy and preeclampsia studies
- 3D Printing in Biomedical Research
- Trypanosoma species research and implications
- Cancer-related molecular mechanisms research
Oregon State University
2011-2017
Swedish Veterinary Agency
2011-2013
Erasmus Hospital
2004-2005
Université Libre de Bruxelles
2002-2004
The mutualistic endosymbiosis between cnidarians and dinoflagellates is mediated by complex inter-partner signaling events, where the host cnidarian innate immune system plays a crucial role in recognition regulation of symbionts. To date, little known about diversity thrombospondin-type-1 repeat (TSR) domain proteins basal metazoans or their potential cnidarian-dinoflagellate mutualisms. We reveal large diverse repertoire TSR seven anthozoan species, show that model sea anemone Aiptasia...
Optimized laboratory conditions for research models are crucial the success of scientific projects. This includes controlling entire life cycle, having access to all developmental stages and maintaining stable physiological conditions. Reducing cycle a model can also enhance biological material speed up genetic tool development. Thus, we optimized rearing sea anemone Nematostella vectensis, cnidarian study embryonic post-metamorphic processes, such as regeneration. We adopted semi-automated...
The symbiosis between host cnidarians, such as corals and anemones, their dinoflagellate symbionts is regulated by largely undescribed mechanisms that stabilize the during normal conditions but lead to breakdown, or cnidarian bleaching, stress. Previous transcriptomic studies identified sphingosine rheostat a putative regulatory pathway. rheostat, which includes sphingolipids (Sph) 1-phosphate (S1P), key homeostatic cell pathway known function in fate immunity animals. This study explores...
This study aimed at identifying all of the type I interferon (IFN) genes horse and monitoring their expression in equine cells on vitro induction. We identified 32 putative IFN loci chromosome 23 an unplaced genomic scaffold. A phylogentic analysis characterized these into 8 different classes, that is, functional for 6 IFN-α, 4 IFN-β, IFN-ω (plus pseudogenes), 3 IFN-δ 1 pseudogene), IFN-κ IFN-ɛ, plus IFN-ν pseudogene, belonging to what has previously been called IFN-αω. Our analyses indicate...
Palytoxin is considered one of the most potent biotoxins. As palytoxin-induced cancer cell death mechanisms remain to be elucidated, we investigated this effect on various leukemia and solid tumor lines at low picomolar concentrations. palytoxin did not affect viability peripheral blood mononuclear cells (PBMC) from healthy donors create systemic toxicity in zebrafish, confirmed excellent differential toxicity. Cell was characterized by a multi-parametric approach involving detection nuclear...
The flux of CO2 diffusing inside a new type bioreactors has been measured experimentally. This geoinspired bioreactor consists partially filled cylinder rotating around its axis tilted vertically, thus mimicking the precession motion Earth. height fluid is chosen equal to two radii in order for first Kelvin mode be resonant. diffuses through membrane located at bottom liquid. partial pressure above free surface as function time. temporal evolution modeled by presence diffusive layers with no...
Astroviruses are becoming a growing concern in veterinary and public health. To date there no registered vaccines against astrovirus-induced disease, mostly due to the difficulty cultivate astroviruses high titer for vaccine development using conventional techniques. As means circumvent this drawback, we have developed stably transfected mink fetal cells BHK21 constitutively expressing full-length truncated capsid proteins of two distinct genotypes astrovirus. Protein expression these was...
Abstract Optimized laboratory conditions for research models are crucial the success of scientific projects. This includes control entire life cycle, access to all developmental stages and maintaining stable physiological conditions. Reducing cycle a model can also enhance biological material speed up genetic tool development. Thus, we optimized rearing sea anemone Nematostella vectensis , cnidarian study embryonic post-metamorphic processes, such as regeneration. We adopted semi-automated...