A5103215803- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Cytomegalovirus and herpesvirus research
- Animal Virus Infections Studies
- Tuberculosis Research and Epidemiology
- Clostridium difficile and Clostridium perfringens research
- Viral Infections and Immunology Research
- Antibiotic Use and Resistance
- HIV Research and Treatment
- Microbial infections and disease research
- Aquaculture disease management and microbiota
- Immune cells in cancer
- Wildlife Ecology and Conservation
- Bacterial Identification and Susceptibility Testing
- Lipid metabolism and disorders
- Immunotherapy and Immune Responses
- Phagocytosis and Immune Regulation
- Immune Cell Function and Interaction
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- TGF-β signaling in diseases
- Herpesvirus Infections and Treatments
- Nutrition, Genetics, and Disease
- Parasites and Host Interactions
- Immune responses and vaccinations
- Reproductive Physiology in Livestock
IVC Evidensia
2023-2024
Innovative Vector Control Consortium
2024
Linköping University
2016-2019
Swedish Veterinary Agency
2013-2019
Capital Region of Denmark
2019
Copenhagen University Hospital
2011
Rigshospitalet
2000
Biochemical assessment of gonadal function during maturation in girls and adult women can be troublesome. With the recent advent specific assays for peptides inhibin A B, it might possible to achieve a clearer picture events. We therefore determined serum levels A, FSH, LH estradiol cross-sectional study 403 healthy schoolgirls (aged 6–20 yr) relation age stage puberty 181 nonpregnant 20–32 menstrual cycle. In addition, B were measured daily throughout cycle 10 women. Levels are low or...
Abstract Background Mycoplasma bovis ( M. ) is an emerging bovine pathogen, leading to significant economic losses in the livestock industry worldwide. Infection can result a variety of clinical signs, such as arthritis, pneumonia, mastitis and keratoconjunctivitis, none which are -specific. Laboratory diagnosis therefore important. Serological tests detect antibodies considered effective indicator infection herd often used test. Combined with judgement, it also be implement control...
In countries with a high prevalence of tuberculosis there is coincident helminth infections that might worsen disease outcome. While Mycobacterium (Mtb) gives rise to pro-inflammatory Th1 response, Th2 response typical infections. A strong has been associated decreased protection against tuberculosis.We investigated the direct effect helminth-derived antigens on human macrophages, hypothesizing helminths would render macrophages less capable controlling Mtb. Measuring cytokine output,...
Several species-specific PCR assays, based on a variety of target genes are currently used in the diagnosis Mycoplasma bovis infections cattle herds with respiratory diseases and/or mastitis. With this diversity methods, and development new methods formats, regular performance comparisons required to ascertain diagnostic quality. The present study compares that six national veterinary institutes across Europe. Three different sample panels were compiled analysed assess analytical...
Tuberculosis remains a big threat, with 1.6 million deaths in 2017, including 0.3 among patients HIV. The risk of developing active disease increases considerably during an HIV coinfection. Alveolar macrophages are the first immune cells to encounter causative agent <i>Mycobacterium tuberculosis</i>, but granuloma formation other recruited order combat bacteria. Here, we have investigated effect efferocytosis apoptotic neutrophils by <i>M. tuberculosis</i> and...
Antimicrobial resistance is one of the largest threats to global health. In society as well in healthcare facilities, antimicrobial rapidly increasing with main reason being overuse and misuse antibiotics combined inadequate infection prevention. For humans, dental care accounts for about 10% all antibiotic prescriptions, making it an important target stewardship interventions. Corresponding figures veterinary are currently lacking but disease frequently diagnosed small animals. An first...
Infections with Aleutian disease virus (ADV) cause a progressive hypergammaglobulinemia, immune complex formation and plasma cell infiltrations in internal organs which induce multi-systemic high mortality. Serum ADV antibodies have traditionally been diagnosed counter immunoelectrophoresis (CIEP) as gold standard for qualitative assessment separating infected from non-infected animals, but less laborious ELISA methods confirmed to be equally sensitive. A way simplify the diagnostics further...
Astroviruses are becoming a growing concern in veterinary and public health. To date there no registered vaccines against astrovirus-induced disease, mostly due to the difficulty cultivate astroviruses high titer for vaccine development using conventional techniques. As means circumvent this drawback, we have developed stably transfected mink fetal cells BHK21 constitutively expressing full-length truncated capsid proteins of two distinct genotypes astrovirus. Protein expression these was...
Canine gastroenteritis (CGE) is a common cause for seeking veterinary care in companion animal medicine and an area where antibiotics have been reported to be widely used. Therefore, creating relevant benchmarks antibiotic use CGE important when implementing analyzing stewardship interventions. The aim of this paper was describe the level temporal trend systemic Sweden between 2020 2023.
Background and Aims: Certain persistent pollutants, such as PCBs DDTs, are thought to cause endocrine disruption. We examined the serum hormone profile in boys at puberty age regard their prenatal pollutant exposures. Methods: In 1986-1987 cord blood was sampled from a Faroese birth cohort kept frozen. 2000-2001, members were invited for clinical examinations 14 years underwent Tanner staging and, finger length measurement, assessment. Of 436 participating (85%), complete data available 361...