- Voice and Speech Disorders
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Cancer Studies
- Airway Management and Intubation Techniques
- Urban and spatial planning
- Ear and Head Tumors
- Construction Project Management and Performance
- Educational Technology and Optimization
- Head and Neck Anomalies
- Bone Tissue Engineering Materials
- Sinusitis and nasal conditions
- Genomic variations and chromosomal abnormalities
- Healthcare Systems and Technology
- Diagnosis and Treatment of Venous Diseases
- Structural mechanics and materials
- Pediatric Urology and Nephrology Studies
- Cancer and Skin Lesions
- Pneumothorax, Barotrauma, Emphysema
- Renal cell carcinoma treatment
- Reconstructive Surgery and Microvascular Techniques
- Adrenal and Paraganglionic Tumors
- Calcium Carbonate Crystallization and Inhibition
- Collagen: Extraction and Characterization
Cedars-Sinai Medical Center
2018-2024
University of Craiova
2015-2024
University of Medicine and Pharmacy of Craiova
2024
Technical University of Cluj-Napoca
2019
Sinai Hospital
2018
Harvard University
2011-2016
Massachusetts General Hospital
2011-2016
Harvard University Press
2012
Case Western Reserve University
2006-2012
University School
2012
Objectives: Photoangiolytic laser treatment of recurrent respiratory papillomatosis (RRP) is effective, but does not reliably prevent recurrence. Therefore, sublesional injections the antiangiogenic agent bevacizumab (Avastin) were given to assess adjunctive effect on disease Since a new therapeutic modality for RRP, there also primary safety objectives determine whether was negative impact voice and local or systemic complications. Methods: A prospective open-label investigation conducted...
Increasing evidence supports the use of laryngeal injections antiangiogenic agent bevacizumab (Avastin) for adjuvant treatment recurrent respiratory papillomatosis (RRP). A recent prospective open-label investigation, approved by US Food and Drug Administration, employing 12.5 mg sublesional demonstrated single-site efficacy without complications; however, safety multiple-site higher dosing has not yet been reported. The primary objective this study was to report on increased doses RRP.Two...
Objectives: Clinical management of phonotraumatic vocal fold lesions (nodules, polyps) is based largely on assumptions that abnormalities in habitual levels sound pressure level (SPL), fundamental frequency (f0), and/or amount voice use play a major role lesion development and chronic persistence. This study used ambulatory monitoring to evaluate if significant differences exist between patients with normal matched controls. Methods: Subjects were 70 adult females: 35 nodules or polyps age-,...
The morbidity of glottic insufficiency resulting from unilateral vocal fold immobility may significantly compromise postoperative recovery in patients with decreased pulmonary reserve or inability to protect their airway. Injection medialization laryngoplasty is an effective means treating due immobility. purpose this study present our experience bedside transoral injection the immediate period.Case series chart review.Academic tertiary care hospital.Patient demographics, clinical...
Objectives: Wide-field transcervical partial laryngectomy often precludes tracheotomy decannulation. It is done infrequently today, primarily because of the popularity chemotherapy-radiotherapy treatment regimens and limited enthusiasm for using after failed radiotherapy. We sought to identify a new reconstructive technique that would provide an alternative total in as many patients possible. Methods: performed retrospective examination 15 who underwent single-stage wide-field with...
Objective To identify patterns of failure following transcervical medialization laryngoplasty for unilateral vocal fold paralysis and describe indications revision techniques optimal outcomes. Study Design Case series with chart review. Setting Tertiary care center. Subjects Methods Thirty‐nine consecutive patients between January 2005 April 2014 undergoing failed primary were identified. Demographics, etiology, stroboscopic assessment, surgical recorded. Patient self‐assessment using the...
Abstract Objectives/Hypothesis. To determine whether respiratory compromise from bilateral vocal fold impairment (paralysis) can be objectively alleviated by reinnervation and pacing. Methods. A patient with paramedian folds synkinesis had a tracheotomy for stridor after laryngeal nerve injury Miller Fisher syndrome. One posterior cricoarytenoideus (PCA) received nerve‐muscle pedicle fitted perineural electrode pacemaker stimulation. The airway was evaluated endoscopically spirometry up to 1...
Management of early glottic cancer subsequent to failed radiotherapy is challenging, especially in balancing oncological control and function preservation. Patients frequently have been incentivized against surgical management thus undergone as initial treatment. This history compounds the difficulty discussions about after recurrence. Typically, endoscopic salvage has less morbidity than transcervical partial laryngectomy clearly desirable over total laryngectomy. However, there are...
Objectives: We assessed the likelihood of arytenoid dislocation during intubation through application controlled force. Methods: Six cadaveric human larynges were mounted in an apparatus for simulating forcible collision with complexes. An endotracheal tube tip probe (ETTP) was used to push one complex, and a non-slip (NSP) tested on other. Increasing pressure applied until probes either slipped or reached 5 kg Dissection then performed assess integrity cricoarytenoid ligament. The forces...
Abstract A collagen‐apatite composite designed as a load‐bearing bone substitute implant is used to characterize the relationship between morphology and in vivo behavior. This nanophase (NBS) studied morphologically using nondestructive imaging technique biologically rodent subcutaneous model. Porosity pore interconnectivity are correlated with histological outcomes showing cellular invasion occurs average sizes below 100 μm. Crosslinking D‐ribose shown affect infiltration dose‐response...
Objectives: Mandibular tori have been identified as a contributing factor in difficult exposure during intubation. However, no investigation has measured the effect of mandibular on glottic suspension microlaryngoscopy (SML). The objective this study was to measure how size and location affect simulated SML at different thyromental distances. Methods: Suspension modeled an anatomically accurate skull larynx with distances between 6 12 cm. were by protruding screws 5 15 mm from lingual aspect...
An HIV+ patient presented with human monkeypox and ENT was consulted to rule out a deep neck abscess. Flexible nasopharyngolaryngoscopy showed severe laryngeal edema new findings consistent HMPX. The monitored for potential difficult airway situation, started on appropriate treatment, symptom resolution.
This cross-sectional study examines the gender diversity of speakers at American Academy Otolaryngology–Head and Neck Surgery (AAO-HNS) annual meetings over a 14-year period.
Background: Conditions associated with BRCA1/2 pathogenic (PVs) or likely variants (LPVs) are often severe. The early detection of carrier status is ideal, as it provides options for effective case management. Materials and Methods: study involved 58 patients a personal familial history breast cancer (BC) who underwent genetic testing at the Regional Centre Medical Genetics Dolj over three-year period. An immunohistochemical panel (HER2, ER, PR, Ki-67) was used to define molecular subtypes...
In the paper presented are given oscillation amplitude threshold compaction and vibrating platform, stiffness viscosity of concrete, frequency movement on compacting concrete.
Chronic rhinosinusitis (CRS) has long been associated with vocal dysfunction. However, studies quantifying the presence of voice dysfunction in CRS patients or effects functional endoscopic sinus surgery (FESS) are sparse. The goal this study was to determine voice-related quality life undergoing FESS for using validated Voice Related Quality Life Survey (VRQL). We correlated preoperative VRQL scores Sino-Nasal Outcome Test (SNOT-22) scores, and we determined effect on postoperative...
Abstract Background The incidence of recurrent laryngeal nerve injury (RLNI) after heart transplantation has not been well studied. This can manifest as vocal cord dysfunction causing dysphonia. Previous research is limited to aortic, coronary bypass, and valvular surgery. Identifying RLNI important in order more accurately detail complications associated with this major Methods a retrospective study assessing 972 adult patients who underwent orthotopic between 2010‐2019. Primary outcome was...