A5066815833- Nanoplatforms for cancer theranostics
- Metabolism, Diabetes, and Cancer
- Bone health and treatments
- Diabetes Treatment and Management
- Photodynamic Therapy Research Studies
- Quantum optics and atomic interactions
- Cold Atom Physics and Bose-Einstein Condensates
- Bone and Joint Diseases
- Electrospun Nanofibers in Biomedical Applications
- Genomics and Chromatin Dynamics
- Nonlinear Waves and Solitons
- Dental Implant Techniques and Outcomes
- Wound Healing and Treatments
- Advanced Fluorescence Microscopy Techniques
- Nonlinear Photonic Systems
- Laser Material Processing Techniques
- Microtubule and mitosis dynamics
- Surface Treatment and Residual Stress
- Pancreatic function and diabetes
- Photonic and Optical Devices
- Long-Term Effects of COVID-19
- Bone Tissue Engineering Materials
- Antimicrobial agents and applications
- Physics of Superconductivity and Magnetism
- Copper Interconnects and Reliability
Capital Medical University
2016-2025
Shanghai Stomatological Hospital
2020-2025
Peking University
2015-2024
Beijing University of Chemical Technology
2021-2024
Qilu Normal University
2024
East China University of Science and Technology
2024
Ningbo University
2023
Fudan University
2023
Union Hospital
2023
University of California, Los Angeles
2023
Biomedical device-associated infection (BAI) is a great challenge in modern clinical medicine. Therefore, developing efficient antibacterial materials significantly important and meaningful for the improvement of medical treatment people's health. In present work, we developed strategy surface functionalization multifunctional applications. A functionalized polyurethane (PU, widely used biomedical material hernia repairing) (PU-Au-PEG) with inherent antifouling photothermal bactericidal...
Super-resolution structured illumination microscopy (SR-SIM) is an outstanding method for visualizing the subcellular dynamics in living cells. To date, by using elaborately designed systems and algorithms, SR-SIM can achieve rapid, optically sectioned, SR observation with hundreds to thousands of time points. However, real-time still out reach most SIM setups as conventional algorithms image reconstruction involve a heavy computing burden. address this limitation, accelerated algorithm was...
Cationic photosensitizers have good binding ability with negatively charged bacteria and fungi, exhibiting broad applications potential in antimicrobial photodynamic therapy (aPDT). However, cationic often display unsatisfactory transkingdom selectivity between mammalian cells pathogens, especially for eukaryotic fungi. It is unclear which biomolecular sites are more efficient damage, owing to the lack of systematic research same photosensitizer system. Herein, a series aggregation-induced...
Combating implant-associated infections is an urgent demand due to the increasing numbers in surgical operations such as joint replacements and dental implantations. Surface functionalization of implantable medical devices with polymeric antimicrobial antifouling agents efficient strategy prevent bacterial fouling associated infections. In this work, branched (GPEG GEG) were synthesized via ring-opening reaction involving gentamicin ethylene glycol species. Due their rich primary amine...
Abstract Multidrug‐resistant Pseudomonas aeruginosa (MDR‐ P. ) cannot be extirpated with any of the antipseudomonal antibiotics available in clinic because exhibit natural resistance to and form a stable biofilm. Biofilm formed by is leading cause bacterial keratitis which may corneal perforation even blindness. Antibacterial photodynamic therapy (aPDT) promising bactericidal method combatting drug‐resistant bacteria. Unfortunately, use broad‐spectrum aPDT that kills bacteria...
A multifunctional natural polyphenol-functionalized chitosan/gelatin sponge (PCGS) is reported for hemostatic and infected wound therapy.
Multifunctional antibacterial materials have great significance for treating biomedical device-associated infections (BAIs). In the present work, a facile and rational strategy was developed to produce dual-functional implants with osteointegration-promoting properties treatment of BAI. A titanium implant, as representative demo implants, first functionalized ethanediamine-functionalized poly(glycidyl methacrylate) (PGED) brushes. Then, low-molecular-weight quaternized polyethyleneimine...
Abstract Background To compare the accuracy of photogrammetry, intraoral scanning and conventional impression techniques for complete-arch implant rehabilitation. Methods A master cast containing 6 abutment replicas was fabricated. Group PG: digital impressions were taken 10 times using a photogrammetry system; IOS: performed to fabricate impressions; CNV: splinted open-tray technique used definitive casts. The casts digitized with laboratory reference scanner. For all STL files obtained,...
Abstract Implant‐associated infections are the most critical threat to orthopedic surgeries. Various surface‐modification strategies developed impart antibacterial properties and osteogenesis‐promoting abilities surfaces of implants. Nevertheless, a straightforward strategy for constructing functional, stable, bioactive implant surface remains challenging. Here, facile one‐step surface‐bioactivation method is that enhances both anti‐infection capabilities osteointegration performance This...
This study aimed to explore the effects of metformin on osteogenic differentiation alveolar bone marrow mesenchymal stem cells (BMSCs) from type-2 diabetes mellitus (T2DM) patients (DM-BMSCs) and implant osseointegration in rats, screen optimal concentration, investigate whether could protect against adverse impact T2DM BMSC capacity.Different concentrations were administered human-derived BMSCs Wistar rats receiving implants. ALP detection, alizarin red staining, real-time RT-PCR Western...
Abstract Periodontal tissue infection is a chronic destructive inflammatory disease caused by bacteria including anaerobes and facultative anaerobes. Traditional mechanical debridement antibiotic treatments are not effective at removing biofilm from the root surface, resulting in recurrent disease. Antimicrobial photodynamic therapy (aPDT) promising bactericidal method, but it limited oxygen content. Here, an oxygen‐free cationic polymer (HQRB‐SS‐Dex) containing photosensitizer rose bengal...
This paper takes (4+1)-dimensional Fokas equation as an example to introduce ingenious limit approach generate degenerate solutions in detail. Under this technique, we start with describing lump chains and obtain from coupled quickly easily. The complex dynamics of these are shown both three-dimensional plots two-dimensional contour plots. Additionally, find the central area is a very good approximation corresponding rogue wave which can be used formulate waves optical system.
Beyond conventional ferromagnetism and antiferromagnetism, altermagnetism is a recently discovered unconventional magnetic phase characterized by time-reversal symmetry breaking spin-split band structures in materials with zero net magnetization. This distinct not only enriches the understanding of fundamental physical concepts but also has profound impacts on condense-matter physics research practical device applications. Spin-polarized have been observed semiconductors MnTe MnTe2 vanishing...
We investigate the role of external magnetic fields and linearly polarized pump light, especially when their directions are parallel or vertical, on propagation fractional vector vortex beams (FVVBs) through a atomic system. Herein, different configurations lead to various optically selective transmissions FVVBs with topological charge α caused by atoms, which is theoretically demonstrated density matrix visualization analysis experimentally explored Cesium atom vapor. Meanwhile, we find...
Abstract Objectives To investigate the effect of liraglutide on osteogenesis in human alveolar bone marrow mesenchymal stem cells (BMSCs) and influence implant–bone integration rats with T2DM. Subjects methods Extracting BMSCs from alveoli diabetic patients treated insulin. were different concentrations liraglutide. Osteogenesis underlying mechanism investigated via ALP detection, staining, Alizarin Red S Western blotting, RT‐PCR. Liraglutide was given to Wistar GK after implantation, new...