A5034703343- Topological Materials and Phenomena
- Graphene research and applications
- Rare-earth and actinide compounds
- Advanced Condensed Matter Physics
- CRISPR and Genetic Engineering
- Iron-based superconductors research
- ECG Monitoring and Analysis
- Electronic and Structural Properties of Oxides
- Quantum and electron transport phenomena
- Pluripotent Stem Cells Research
- 2D Materials and Applications
- EEG and Brain-Computer Interfaces
- Seismic Imaging and Inversion Techniques
- Superconductivity in MgB2 and Alloys
- Phonocardiography and Auscultation Techniques
- Non-Invasive Vital Sign Monitoring
- Seismic Waves and Analysis
- Drilling and Well Engineering
- Mosquito-borne diseases and control
- Physics of Superconductivity and Magnetism
- Cancer-related gene regulation
- Advanced Optical Imaging Technologies
- Neuroscience and Neural Engineering
- Cancer-related molecular mechanisms research
- Wireless Power Transfer Systems
Shaanxi Normal University
2022-2024
Institute of Physics
2017-2024
Chinese Academy of Sciences
2004-2024
Suzhou Institute of Biomedical Engineering and Technology
2021-2024
Suzhou University of Science and Technology
2024
First Affiliated Hospital of Xiamen University
2024
China Academy of Space Technology
2024
University of Science and Technology of China
2021-2024
National Laboratory for Superconductivity
2017-2024
Anhui University of Science and Technology
2023-2024
We report the magnetoresistance (MR), Hall effect, and de Haas--van Alphen (dHvA) effect studies of single crystals tungsten carbide, WC, which is predicted to be a new type topological semimetal with triply degenerate nodes. With magnetic field rotated in plane perpendicular current, WC shows induced metal-to-insulator-like transition large nonsaturating quadratic MR at low temperatures. As parallel pronounced negative longitudinal only can observed for certain direction current flow. The...
Unconventional superconductivity in bulk materials under ambient pressure is extremely rare among the 3d transition metal compounds outside layered cuprates and iron-based family. It predominantly linked to highly anisotropic electronic properties quasi-two-dimensional (2D) Fermi surfaces. To date, only known example of a Co-based exotic superconductor hydrated cobaltate, NaxCoO2·yH2O, its realized vicinity spin-1/2 Mott state. However, nature these still subject intense debate, therefore,...
Abstract Japanese encephalitis (JE) caused by virus (JEV) poses a serious threat to the world’s public health yet without cure. Certain JEV-infected neural cells express subset of previously identified intrinsic antiviral interferon stimulated genes (ISGs), indicating brain retain autonomous immunity. However, whether this happens in composited remains unclear. Human pluripotent stem cell (hPSC)-derived organoids can model disorders human endemic pathogens such as Zika virus, which may...
Abstract Interacting electrons confined to their lowest Landau level in a high magnetic field can form variety of correlated states, some which manifest themselves Hall effect. Although such states have been predicted occur three-dimensional semimetals, corresponding response has not yet experimentally observed. Here, we report the observation an unconventional quantum limit bulk semimetal HfTe 5 , adjacent effect single electron band at low fields. The additional plateau-like feature...
Abstract Dosage of key regulators impinge on developmental disorders such as FOXG1 syndrome. Since neither knock-out nor knock-down strategy assures flexible and precise protein abundance control, to study hypomorphic or haploinsufficiency expression remains challenging. We develop a system in human pluripotent stem cells (hPSCs) using CRISPR/Cas9 SMASh technology, with which we can target endogenous proteins for dosage control hPSCs at multiple stages neural differentiation. also reveal...
Differentiation of human pluripotent stem cells (hPSCs) into striatal medium spiny neurons (MSNs) promises a cell-based therapy for Huntington's disease. However, clinical-grade MSNs remain unavailable. Here, we developed chemical recipe named XLSBA to generate from embryonic (ESCs). We introduced the γ-secretase inhibitor DAPT accelerate neural differentiation, and replaced protein components with small molecules. Using this optimized protocol could efficiently direct regular ESCs (hESCs)...
Usher syndrome (USH) is the leading cause of inherited combined hearing and vision loss. As an autosomal recessive trait, it affects 15,000 people in United States alone responsible for ~21% blindness 3 to 6% early childhood deafness. Approximately 2/3 patients with suffer from USH2, whom 85% have mutations USH2A gene. Patients affected by USH2 congenital bilateral progressive sensorineural loss retinitis pigmentosa which leads vision. To study molecular mechanisms this disease develop a...
We report the observation of local superconductivity induced at point contact formed between a normal metal tip and WC -- triple topological semimetal with super hardness. Remarkably, maximum critical temperature is up to near 12 K but insensitive tip's magnetism. The lateral dimensions superconducting puddles were evaluated dependencies gap upper field also obtained. These results put constraints on explanation pave pathway for exploring superconductivity.
Beyond conventional ferromagnetism and antiferromagnetism, altermagnetism is a recently discovered unconventional magnetic phase characterized by time-reversal symmetry breaking spin-split band structures in materials with zero net magnetization. This distinct not only enriches the understanding of fundamental physical concepts but also has profound impacts on condense-matter physics research practical device applications. Spin-polarized have been observed semiconductors MnTe MnTe2 vanishing...
Human pluripotent stem cells hold great promise for improving regenerative medicine. However, a risk tumor formation and difficulties in generating large amounts of subtype derivatives remain the major obstacles clinical applications cells. Here, we discovered that zinc finger E-box-binding homeobox 1 (ZEB1) is highly expressed upon differentiation human embryonic (hESCs) into neuronal precursors. CRISPR/Cas9-mediated ZEB1 depletion did not impede neural fate commitment, but prevented...
Abstract Interfaces between materials with different electronic ground states have become powerful platforms for creating and controlling novel quantum of matter, in which inversion symmetry breaking other effects at the interface may introduce additional states. Among emergent phenomena, superconductivity is particular interest. Here, by depositing metal films on a newly identified topological semimetal tungsten carbide (WC) single crystal, interfacial obtained, evidenced from soft...
This study intends to investigate the effects of miR-142-5p encapsulated by serum-derived extracellular vesicles (EVs) on septic acute lung injury (ALI) following remote ischemic preconditioning (RIPC) through a PTEN-involved mechanism. ALI was induced in rats lipopolysaccharide (LPS) injection, 24 h before which RIPC performed via left lower limb. Next, binding affinity between and PTEN identified. EVs were isolated from serum injected into rats. The morphology tissues, pulmonary edema,...
Objectives Coronavirus disease 2019 (Covid-19) is outbreaking globally. We aimed to analyse the clinical characteristics, cardiac injury, electrocardiogram and computed tomography (CT) features of patients confirmed Covid-19 explored prediction models for severity Covid-19. Methods A retrospective single-centre study enrolled 98 laboratory-confirmed patients. Clinical data, CT were collected analysed using Statistical Package Social Sciences software. Results There 46 males 52 females, with...
Abstract The search for topological superconductivity (TSC) is currently an exciting pursuit, since non-trivial superconducting phases could host exotic Majorana modes. However, the difficulty in fabricating proximity-induced TSC heterostructures, sensitivity to disorder and stringent restrictions of intrinsic place serious limitations formidable challenges on materials related applications. Here, we report a new type TSC, namely surface (IS-TSC) demonstrate it layered AuSn 4 with T c 2.4 K....
Tip-induced superconductivity at point contacts on the nonsuperconducting Weyl semimetal TaAs has been reported recently. Meanwhile, both main tetragonal phase and intergrown hexagonal of were identified to be topologically nontrivial according theoretical calculations. Here, we report observation two independent local superconducting states induced formed TaAs, which exhibit distinct temperature dependencies critical magnetic field ${H}_{c2}(T)$. A universal relationship between...
We report a systematic study of the magnetoresistance, Hall effect, and electronic structure in an iodine-intercalated tungsten ditelluride (${\mathrm{WTe}}_{2}\mathrm{I}$) single crystal, which crystallizes centrosymmetric structure. ${\mathrm{WTe}}_{2}\mathrm{I}$ presents significant anisotropic magnetotransport behavior with magnetic field rotated $xz$ $yz$ planes violation Kohler's rule. Unexpectedly, nonsaturating linear magnetoresistance (LMR) was observed under parallel to $z$ axis...
The honeycomb iridate Na2IrO3, as a candidate for the Kitaev model, has drawn increasing attention in recent years. It is rare example of strongly correlated, topologically nontrivial band structure that may have protected quantum spin Hall states. nature its intriguing insulating phase and magnetic order still under debate. In present work, we combine low-temperature scanning tunneling microscopy/spectroscopy density functional theory calculations to show Na2IrO3 exhibits gap 420 meV at 77...