A5040650868- Genomics and Phylogenetic Studies
- Cholesterol and Lipid Metabolism
- Machine Learning in Bioinformatics
- Liver Disease Diagnosis and Treatment
- Mosquito-borne diseases and control
- Peroxisome Proliferator-Activated Receptors
- RNA and protein synthesis mechanisms
- Viral Infections and Vectors
- Virology and Viral Diseases
- Cancer, Lipids, and Metabolism
- Gene Regulatory Network Analysis
- Immune Cell Function and Interaction
- Microbial Metabolites in Food Biotechnology
- Sepsis Diagnosis and Treatment
- Algorithms and Data Compression
- Proteins in Food Systems
- Chromosomal and Genetic Variations
- Diabetes and associated disorders
- Toxin Mechanisms and Immunotoxins
- Bone Tissue Engineering Materials
- T-cell and B-cell Immunology
- Viral Infections and Immunology Research
- Ziziphus Jujuba Studies and Applications
- Fatty Acid Research and Health
- Advanced biosensing and bioanalysis techniques
Nanjing Medical University
2024
Suzhou Municipal Hospital
2024
Northwest A&F University
2018-2022
Sichuan Agricultural University
2022
Jiangsu University
2021
Wuhan Institute of Virology
2019-2020
Chinese Academy of Sciences
2019-2020
Changchun University of Chinese Medicine
2020
University of Chinese Academy of Sciences
2020
Northeastern University
2015
Mosquito-borne flaviviruses infect both mammals and mosquitoes. RNA interference (RNAi) has been demonstrated as an anti-flavivirus mechanism in mosquitoes; however, whether how induce antagonize RNAi-mediated antiviral immunity remains unknown. We show that the nonstructural protein NS2A of dengue virus-2 (DENV2) act a viral suppressor RNAi (VSR). When NS2A-mediated suppression was disabled, resulting mutant DENV2 induced Dicer-dependent production abundant DENV2-derived siRNAs...
Polyetheretherketone (PEEK) is a kind of nontoxic high-performance thermoplastic widely used for medical applications. Compared with other special engineering plastics, PEEK has many excellent properties, such as high temperature resistance, chemical corrosion radiation hydrolysis mechanical good self-lubrication and easy processing. Although been the replacements metallic ceramic implants in field, it biologically inertia, which reduces fusion host bone tissue after implantation. In...
Plums are widely consumed, contain high levels of phenolic compounds, and have strong antioxidant activity. In this study, the main Sichuan cultivars 'Qiangcuili' 'Cuihongli' were used to study changes in appearance, internal quality, activities during fruit development expression phenolic-compound-related structural genes. The results showed that, two plums, total soluble solid sugar contents highest at mature stage. (total phenol content (TPC), flavonoid (TFC), flavanol (TFAC)) trended...
Two-dimensional (2D) barcodes ubiquitously used to label, track and authenticate objects face increasing challenges of being damaged, altered falsified. The past effort in nanomaterials has paved the way for controlled synthesis with desired size, shape function. Due their extremely small sizes, these are promising as next generation that can be added into or mixed interest without noticed. These effectively read owing physical properties by manufacturers, law enforcement security agencies....
OBJECTIVE Induction of mixed or complete chimerism via hematopoietic cell transplantation (HCT) from nonautoimmune donors could prevent reverse type 1 diabetes (T1D). In clinical settings, HLA-matched HCT is preferred to facilitate engraftment and reduce the risk for graft versus host disease (GVHD). Yet autoimmune T1D susceptibility associated with certain HLA types. Therefore, we tested whether induction major histocompatibility complex (MHC)-matched autoimmunity in NOD mouse model T1D....
We determined and analyzed the structural, physicochemical functional properties of Semen Ziziphi Spinosae protein. It shows that SZSP has good processing can become a new plant protein source.
Accurate annotation of different genomic signals and regions (GSRs) from DNA sequences is fundamentally important for understanding gene structure, regulation function. Numerous efforts have been made to develop machine learning-based predictors in silico identification GSRs. However, it remains a great challenge identify GSRs as the performance most existing approaches unsatisfactory. As such, highly desirable more accurate computational methods prediction.In this study, we propose general...
Nonalcoholic fatty liver (NAFL) is increasingly recognized as one of the most common causes chronic disease worldwide. Traditional Chinese medicine (TCM), alternative and complementary medicine, may provide some profound health benefit. “ Jiang-Zhi ” Granule (JZG) was composed based on TCM pathogenesis NAFL: retention inner dampness, heat blood stasis. This study investigated effects JZG X receptor-<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Heat shock 70 kDa protein 8 (HSPA8) and erb-b2 receptor tyrosine kinase 2 (ERBB2) were the promising candidates for milk concentration in dairy cattle revealed through previous RNA sequencing (RNA-Seq) study. The objective of this post-RNA-Seq study was to confirm genetic effects HSPA8 ERBB2 on a large Chinese Holstein population evaluate both genes other production traits. There single-nucleotide polymorphisms (SNPs) identified 11 SNPs by 17 unrelated sires. SNP-rs136632043 had significant...
Simple Sequence Repeats (SSRs) are short tandem repeats of nucleotide sequences. It has been shown that SSRs associated with human diseases and medical relevance. Accordingly, a variety computational methods have proposed to mine from genomes. Conventional rely on high-quality complete genome identify SSRs. However, the sequenced often misses several highly repetitive regions. Moreover, many non-model species no entire With recent advances next-generation sequencing (NGS) techniques,...