A5103448921- Cancer, Lipids, and Metabolism
- Carbon and Quantum Dots Applications
- Cancer, Hypoxia, and Metabolism
- Natural product bioactivities and synthesis
- Adsorption and biosorption for pollutant removal
- Marine and coastal ecosystems
- Protease and Inhibitor Mechanisms
- Gut microbiota and health
- Food composition and properties
- Catalytic Processes in Materials Science
- Microbial Metabolites in Food Biotechnology
- Nanoplatforms for cancer theranostics
- Nanocluster Synthesis and Applications
- Phytoestrogen effects and research
- Physical Unclonable Functions (PUFs) and Hardware Security
- ATP Synthase and ATPases Research
- Advanced Computational Techniques and Applications
- Cryptographic Implementations and Security
- Radio Frequency Integrated Circuit Design
- Environmental and Agricultural Sciences
- Obsessive-Compulsive Spectrum Disorders
- Aortic aneurysm repair treatments
- Electrochemical sensors and biosensors
- Product Development and Customization
- Biocrusts and Microbial Ecology
Xi'an Jiaotong University
2025
Shanghai Jiao Tong University
2009-2024
Lanzhou University
2024
Ministry of Agriculture and Rural Affairs
2024
Zhejiang Hospital
2023
East China Normal University
2010-2022
Ruijin Hospital
2019
Dalian Medical University
2018
University of Florida
2016
Columbus Oncology and Hematology Associates
2016
To study matrix metalloproteinase 2 (MMP-2) effects on transforming growth factor-beta1 (TGF-beta1) activation status and downstream signaling during arterial aging.Western blotting immunostaining showed that latent activated TGF-beta1 are markedly increased within the aorta of aged Fisher 344 cross-bred Brown Norway (30 months age) rats compared with adult (8 rats. Aortic TGF-beta1-type II receptor (TbetaRII), its molecules p-similar to mad-mother against decapentaplegic (SMAD)2/3 SMAD4,...
Understanding the molecular basis and target of traditional medicine is critical for drug development. Celastrol, derived from Trypterygium wilfordii Hook F. ("Thunder God Vine"), a Chinese plant, has been assigned anticancer activities, but its mechanism not well understood. Here, we investigated whether Celastrol could inhibit angiogenesis-mediated tumor growth and, if so, through what mechanism. When given s.c. to mice bearing human prostate cancer (PC-3 cell) xenografts, (2 mg/kg/d)...
Hypoxia-inducible factor-1 (HIF-1), consisting of oxygen-sensitive HIF-1alpha and constitutively expressed HIF-1beta subunits, is a master transcriptional activator for cellular response to hypoxia. To explore direct HIF-1 targets, here we used differential gel electrophoresis (DIGE) compare the HIF-1-regulated proteins between leukemic U937T-cell line with without conditional induction protein by tetracycline-off system. Among upregulated identified, mRNA levels annexin A1,...
Scope Consumption of inulin could affect the intestinal microbiota composition. Hereby, it is aimed to investigate microbial community restoration process when supplementation terminated (i.e., secondary effect). Methods and results The current study investigates response to/after high (Inulin‐H) low (Inulin‐L) dosage or sequential antibiotics (Anti‐Inulin‐L) supplementation, based on analysis 16S rRNA gene sequences in C57BL/6 mice. number significantly changed genera highest Anti‐Inulin‐L...
The rapid development of the economy and society has led to a expansion volume territorial resource data in China, which brought certain difficulties land engineering industry. However, ArcGIS software not only overcomes many inconveniences statistics, but also can be applied all aspects use change. It modify, organize output final change statistics summary table huge one by one. operation is simple query convenient. This article analyzes application analysis unused reserve resources,...
Bacterial infections seriously retard skin wound healing. To enhance the antibacterial efficiency and subsequent regeneration, a core-shell structured therapeutic platform, named FZAM, was designed with multiple antimicrobial pathways. FZAM consists of nanosized Fe3O4 as core ZIF-8 loaded Au nanoparticles (NPs) maltodextrin shell. NPs form heterojunction that generates hyperthermia abundant reactive oxide species (ROS) under near-infrared (NIR) irradiation. This also exhibits outstanding...
The distinct topographic Hox expression patterns observed in vascular smooth muscle cells (VSMCs) of the adult cardiovascular system suggest that these transcriptional regulators are critical for maintaining region-specific physiological properties blood vessels. To test this proposition, we expanded Hoxc11 domain normally restricted to lower limbs by utilizing an innovative integrated tetracycline regulatory and Transgelin promoter elements induce universally VSMCs transgenic mice. Ectopic...
Carbon dots (CDs), as a new member of carbon nanomaterial family, have aroused great interest since their discovery in 2004. Because outstanding water solubility, high sensitivity and selectivity to target analytes, low toxicity, favorable biocompatibility, excellent photostability, researchers from diverse disciplines come together further develop the fundamental properties CDs. Many methods for production CDs been reported, therein, hydrothermal solvothermal technology needs simple...
A facile hydrothermal method has been presented to prepare free-standing nanoporous Cu foils (NPCFs) having a thickness of ~1.4 μm and an area up ~10 cm2, which were grown on the inwall Teflon-lined autoclave by assembling reducing CuxO nanoparticle intermediates then peeling themselves off in cooling period reaction. The pore sizes NPCFs can be adjusted varying reaction time. It is observed that with water absorbed inside their nanopores show excellent flexibility while dried ones exhibit...
PRESENT, proposed by A. Bogdanov et al. in CHES 2007, is an ultra-lightweight symmetric cipher for extremely constrained environments such as RFID tags and sensor networks. In this article, a representative platform, 0.25 μm 1.8 V standard cell circuit to complement the simulation-based ASIC experimental environment built acquire power data. According fact that consumption of digital implemented CMOS technology depends on data processing, we create hypothetical model differential analysis...
A current challenge is finding an effective and safe treatment for severely disabled patients with Tourette's syndrome (TS) comorbid psychiatric disorders, in whom conventional treatments have failed. The authors aimed to evaluate the utility of globus pallidus internus deep brain stimulation (GPi-DBS) combined bilateral anterior capsulotomy treating these clinically challenging patients.
Subterranean estuaries are highly dynamic in processing dissolved inorganic nitrogen (DIN). Here we investigate DIN turnover surface sediments (0–20 cm depth) at the higher, medium and lower intertidal of a seepage face, i.e., outer "mouth" subterranean estuary, during four consecutive seasons Sanggou Bay, China. Throughout studied period, ammonium (NH4+) nitrite (NO2−) concentrations sampled porewaters did not vary significantly with depth or season. In contrast, peaks porewater nitrate...
Corals rely on a symbiotic relationship with algae (zooxanthellae), which reside in the host tissue and play critical role for metabolism through photosynthesis, respiration, carbon translocation, calcification. These processes affect coral reefs different scales from cellular to organismal ecosystem levels. A process-based dynamic model was developed coupled one-dimensional (1-D) biogeochemical describe translocation at level, calcification ion transport polyp components (i.e., coelenteron,...
ABSTRACT Biocrusts play an essential role in maintaining ecosystem stability, which is common arid and semi‐arid areas. Although there have been some previous studies on the stoichiometry of biocrust subsoil grazing systems, further research needed to assess effects varying intensities. Four gradients were established investigate change mechanism under conditions, considering its seasonal response. These findings revealed that biocrusts' coverage their chlorophyll content showed a parabolic...
According to the realistic requirement of forest industry production cost-management, system divides into four modules: login control module, maintenance data calculation querying and printing module. In this paper, JSP technology [ is applied in design implementation actual cost It can achieve cost-management analysis accounting effectively, share resources on network platform, provide reliable for corporate executives.