A5045203312- Chronic Myeloid Leukemia Treatments
- Craniofacial Disorders and Treatments
- HIV Research and Treatment
- Graphene and Nanomaterials Applications
- HIV, Drug Use, Sexual Risk
- Ferroelectric and Piezoelectric Materials
- School Health and Nursing Education
- Obesity, Physical Activity, Diet
- Acute Lymphoblastic Leukemia research
- Machine Learning in Bioinformatics
- Advanced biosensing and bioanalysis techniques
- HIV/AIDS Research and Interventions
- Chronic Lymphocytic Leukemia Research
- HER2/EGFR in Cancer Research
- Connective tissue disorders research
- Advanced Sensor and Energy Harvesting Materials
- Nanoparticle-Based Drug Delivery
- Hematopoietic Stem Cell Transplantation
- Toxin Mechanisms and Immunotoxins
- Smoking Behavior and Cessation
- LGBTQ Health, Identity, and Policy
- Acute Myeloid Leukemia Research
- Nanoplatforms for cancer theranostics
- Infectious Encephalopathies and Encephalitis
- Cleft Lip and Palate Research
Wenzhou Medical University
2024-2025
Hangzhou DAC Biotech (China)
2025
Lishui Central Hospital
2025
Wuhan University of Technology
2024
Shanghai Children's Medical Center
2024
Shanghai Jiao Tong University
2024
Antibody-drug conjugates (ADCs) offer targeted cancer therapy by delivering cytotoxic agents directly to tumor cells. However, challenges such as relapse, resistance, and diverse patient needs drive ongoing innovation in ADC development. Exploration of new small-molecule toxins with unique antitumor toxicity profiles is crucial. Tub114, a novel Tubulysin B analog hydrophilic ethylene glycol moiety, has been conjugated the anti-HER2 antibody DX-CHO9, forming DX126-262. This study examines...
Acute myeloid leukaemia (AML) is a highly heterogeneous disease, exhibiting diverse subtypes according to the characteristics of tumour cells. The immunophenotype one aspects acquired routinely through flow cytometry in diagnosis AML. Here, we characterized antigen expression paediatric AML cases across both morphological and molecular genetic subgroups. We discovered subgroup patients with unfavourable prognosis that can be immunologically characterized, irrespective FAB results or...
Summary This study delivers a comprehensive evaluation of the efficacy and pharmacokinetics high‐dose methotrexate (HDMTX) in large cohort Chinese paediatric acute lymphoblastic leukaemia patients. A total 533 patients were included prognostic analysis. An association was observed between lower steady‐state MTX concentrations (<56 μmol/L) poorer outcomes intermediate‐/high‐risk (IR/HR) Subgroup analysis further revealed that this relationship prognosis even more pronounced with MLL...
Congenital muscular torticollis (CMT) is a more common childcare disease, which belongs to muscle-skeletal system diseases, and in newborns. The disease mainly due congenital contracture chest locks, leads asymmetric head neck. For such clear diagnosis treatment the early days an important way improve prognosis of children. Compared with X-ray film, CT, MRI, ultrasound examination has advantages low cost, short time, no exposure radiation during examination. Moreover, can provide objective...
Abstract Ferroelectric polymers with robust electrical polarization have been extensively investigated for capacitive energy storage. However, their inherent ferroelectric hysteresis loss limits the discharged density and compromises efficiency. Here, a heterogeneous nanolayered composite of polymer poly(vinylidene fluoride‐trifluoroethylene) (P(VDF‐TrFE)) Al 2 O 3 is presented, which effectively mitigates while maintaining high enhanced breakdown strength. Phase‐field simulations indicate...
1. McNeill A, Brose L, Calder R, Hitchman S, Hajek P, McRobbie H. E-cigarettes: an evidence update: A report commissioned by Public Health England. London: England; 2015;chap 3. https://assets.publishing.serv.... Accessed November 22, 2021. Google Scholar
Objective: To investigate the distribution of mitochondrial haplogroups and their correlation with neurocognitive disorder (NCD) in HIV positive individuals. Methods: Baseline data were from prospective cohort study comparative aging research Taizhou Zhejiang province January to December, 2017. A cross-sectional survey was performed 448 Sanger method used for sequencing genotyping whole genome NCD prevalence individuals assessed by Mini-mental State Examination (MMSE) questionnaire...