A5035399348- Estrogen and related hormone effects
- Inflammatory mediators and NSAID effects
- Endoplasmic Reticulum Stress and Disease
- Synthesis and biological activity
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Pancreatic and Hepatic Oncology Research
- Transgenic Plants and Applications
- RNA Research and Splicing
- Cancer Research and Treatments
- Spondyloarthritis Studies and Treatments
- Cancer Genomics and Diagnostics
- Biosimilars and Bioanalytical Methods
- Gastroesophageal reflux and treatments
- Neural and Behavioral Psychology Studies
- Musculoskeletal synovial abnormalities and treatments
- Metabolomics and Mass Spectrometry Studies
- HER2/EGFR in Cancer Research
- EEG and Brain-Computer Interfaces
- Cancer-related molecular mechanisms research
- Gastrointestinal motility and disorders
- Peripheral Nerve Disorders
- Breast Lesions and Carcinomas
- Drug Transport and Resistance Mechanisms
- Gastric Cancer Management and Outcomes
Tianjin Medical University General Hospital
2025
Tohoku University
2022-2023
Fujian Medical University
2013-2021
Zhangzhou Municipal Hospital of Fujian Province
2013-2021
Shanghai Normal University
2021
United States Food and Drug Administration
2019
Cleveland State University
2010-2011
Nanyang Technological University
2011
Based on endoscopic ultrasonography (EUS) radiomics and clinical data, we constructed a model nomogram for identifying benign malignant pancreatic lesions, explored the diagnostic performance of these two prediction models. Images data 151 patients with lesions detected by EUS from January 2018 to September 2023 were retrospectively collected. The randomly divided into training set validation at ratio 7:3. Through feature extraction screening images, calculated score (rad-score) realize...
Patterning of the animal embryo's antero-posterior (AP) axis is dependent on spatially and temporally regulated Hox gene expression. The murine Hoxd4 has been proposed to harbour two promoters, an upstream promoter P2, a downstream P1, that lie 5.2 1.1 kilobase pairs (kb) coding region respectively. evolutionarily conserved microRNA-10b (miR-10b) lies in genomic locus intron separating non-coding exons 4 5 P2 transcript directly adjacent P1 promoter. transcription by 3′ neural enhancer...
ABSTRACT In this work, a liquid chromatography coupled with electrospray ionization mass spectrometry (LC‐ESI‐MS) method was developed and validated for quantification of bile acids in fecal materials. Co‐eluting matrix impurities materials have been shown to greatly suppress the analytes spectrometry, which is known as effect. To correct large quantitative errors caused by effect, we scheme that combined standard addition internal (SA‐IS). The sample pretreatment involved single step...
Endoplasmic reticulum (ER)-associated degradation (ERAD) is a protein quality control process that eliminates misfolded proteins from the ER. DnaJ homolog subfamily C member 10 (ERdj5) disulfide isomerase family accelerates ERAD by reducing bonds of aberrant with help an ER-resident chaperone BiP. However, detailed mechanisms which ERdj5 acts in concert BiP are poorly understood. In this study, we reconstituted vitro system monitors ERdj5-mediated reduction disulfide-linked J-chain...
Abstract Background Carpal tunnel syndrome (CTS) is the most common entrapment symptom in peripheral nerves. High-frequency ultrasound (HFUS) widely used diagnosis of CTS. Virtual Touch Tissue Imaging and Quantification (VTIQ), which provides more information about hardness organization, to diagnose However, data diagnostic value them various degrees CTS are limited. Whether combination HFUS VTIQ can improve efficiency also remains unknown. The study aimed explore whether could Methods A...
JCC76 is a novel nimesulide analog that selectively inhibits the human epidermal growth factor receptor 2 (HER2) overexpressing breast cancer cell proliferation and tumor progression. To support further pharmacological toxicological studies of JCC76, rapid method using liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) has been developed validated for quantification compound in rat plasma. A C₁₈ column was used chromatographic separation, mobile phase...
Aim: Contract research organizations and pharmaceutical firms have performed stability testing using one of two methods: storing in the freezer a single tube matrix for each quality control concentration (Method 1), followed by aliquoting analysis; three tubes concentration, analysis 2). This project was conducted to determine if there were detectable differences between Method 1 2. Methodology: Five model drugs selected: teriflunomide (stable compound) acetyl salicylic acid, simvastatin,...
Objective To search one ultrasonic method which could evaluate gastric emptying function accurately.Methods The time of 74 normal volunteers were measured by radioisotope scanning and different methods including antrum area,gastric volume whole cylinder method.Results related best with those (r =0.79).The was no significant difference between the radionuclide (P ＞0.05).Compared scanning,those area had differences.Conclusions can accurately reflect function. Key words:...
Objective To evaluate the diagnostic value of virtual touch imaging quantification (VTIQ) technique in differential diagnosis between benign and malignant breast lesions. Methods From September to December 2015, data 115 lesions 100 patients confirmed by pathology on conventional ultrasound (2DUS) VTIQ were retrospectively analyzed. The nodules examined 2DUS firstly then classified reporting system (BI-RADS). maximum, minimum average shear wave velocity (SWV) values obtained from...
Abstract Even when making arbitrary decisions, people tend to feel varying levels of confidence, which is associated with the pre-stimulus neural oscillation brain. We investigated confidence in a pure subjective judgment task, and how this was predicted by alpha oscillations. Participants made judgments where their prior experience seems be helpful but actually useless, fluctuating related choice boundary process rather than evidence accumulation process, suggesting participants underwent...