A5011228892- Cell Image Analysis Techniques
- 14-3-3 protein interactions
- Lipid Membrane Structure and Behavior
- Advanced Biosensing Techniques and Applications
- Force Microscopy Techniques and Applications
- Genetics, Bioinformatics, and Biomedical Research
- Surfactants and Colloidal Systems
- Advanced Fluorescence Microscopy Techniques
- AI in cancer detection
- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Mitochondrial Function and Pathology
- ATP Synthase and ATPases Research
- Image Processing Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- biodegradable polymer synthesis and properties
- Ubiquitin and proteasome pathways
- Diatoms and Algae Research
- Microfluidic and Bio-sensing Technologies
- Microplastics and Plastic Pollution
- Microfluidic and Capillary Electrophoresis Applications
- Peptidase Inhibition and Analysis
- Alzheimer's disease research and treatments
- Advanced Electron Microscopy Techniques and Applications
- Protease and Inhibitor Mechanisms
European Molecular Biology Organization
2023
Carl Zeiss (Germany)
2009-2014
University of Stuttgart
2005-2007
Max Planck Institute of Colloids and Interfaces
1997-1999
Max Planck Society
1999
Phosphatidylinositol-4-kinase-IIIbeta (PI4KIIIbeta) is activated at the Golgi compartment by PKD-mediated phosphorylation. Subsequent mechanisms responsible for continuous PtdIns(4)P production membranes and potential interaction partners of PI4KIIIbeta are unknown. Here we identify phosphoserine/-threonine binding 14-3-3 proteins as novel regulators activity downstream this The PI4KIIIbeta-14-3-3 interaction, evident from GST pulldowns, co-immunoprecipitations bimolecular fluorescence...
Localization of newly synthesized poly(3hydroxybutyrate) (PHB) granules was determined by confocal laser scanning fluorescence microscopy Nile red-stained cells and transmission electron (TEM). PHB living Caryophanon latum at the early stages accumulation were frequently found or close to cytoplasmic membrane. TEM analysis same culture revealed electron-translucent globular structures resembling that nonrandomly distributed in cell lumen but Immunogold labeling using PHB-specific antiserum...
Enteropathogenic Escherichia coli (EPEC) is a human intestinal pathogen and major cause of diarrhoea, particularly among infants in developing countries. EPEC target the Map EspF multifunctional effector proteins to host mitochondria – organelles that play crucial roles regulating cellular processes such as programmed cell death (apoptosis). While both molecules interfere with ability maintain membrane potential, plays predominant role responsible for triggering death. To learn more about...
Images document scientific discoveries and are prevalent in modern biomedical research. Microscopy imaging particular is currently undergoing rapid technological advancements. However for scientists wishing to publish the obtained images image analyses results, there date no unified guidelines. Consequently, microscopy data publications may be unclear or difficult interpret. Here we present community-developed checklists preparing light analysis publications. These offer authors, readers,...
Abstract Confocal Microscopy has evolved from a technique used by specialists only, to of every day use. In biomedical research, the use biomarkers like Green Fluorescent Protein (GFP) pushed confocal microscopy hands few into numerous labs biologists doing basic and applied research. The combination fluorescence non—tactile surface measurements proven be method choice for many applications in materials Changing demands both fields have lead development new instruments enabling researchers...
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive loss of cognitive functions. The pathology AD shows strong degeneration neuritic processes, the presence intracellular neurofibrillary tangles and extracellular amyloid plaques. According to hypothesis amyloid–β peptide (Aβ), which accumulates in brain patients suffering from AD, major pathogenic force this disorder. Therefore, reduction deposits or inhibition Aβ fibrillogenesis promising target for...