A5073528681- Plant nutrient uptake and metabolism
- Plant Molecular Biology Research
- Hemoglobinopathies and Related Disorders
- Ubiquitin and proteasome pathways
- Cancer-related gene regulation
- Animal Disease Management and Epidemiology
- Blood disorders and treatments
- Polysaccharides and Plant Cell Walls
- Zoonotic diseases and public health
- Erythrocyte Function and Pathophysiology
- Congenital heart defects research
- Signaling Pathways in Disease
- Plant tissue culture and regeneration
- Polymer-Based Agricultural Enhancements
- Plant-Microbe Interactions and Immunity
- Rice Cultivation and Yield Improvement
- Yersinia bacterium, plague, ectoparasites research
Institute of Hematology & Blood Diseases Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Sichuan Agricultural University
2017-2023
Outbreaks of zoonotic diseases are accelerating at an unprecedented rate in the current era globalization, with substantial impacts on global economy, public health, and sustainability. Alien species invasions have been hypothesized to be important by introducing both existing novel pathogens invaded ranges. However, few studies evaluated generality alien facilitating zoonoses across multiple host parasite taxa worldwide. Here, we simultaneously quantify role 795 established hosts 10,473...
Abstract Translational control is crucial for protein production in various biological contexts. Here, we use Ribo-seq and RNA-seq to show that genes related oxidative phosphorylation are translationally downregulated during heart regeneration. We find Nat10 regulates the expression of Uqcr11 Uqcrb mRNAs mouse human cardiomyocytes. In mice, overexpression cardiomyocytes promotes cardiac regeneration improves function after injury. Conversely, treating neonatal mice with Remodelin—a...
Ubiquitin-specific proteases (UBPs) process deubiquitination in eukaryotic organisms and are widely involved plant development responses to environmental stress. However, their role cell death immunity remains largely unknown. Here, we identified a rice lesion mimic mutant (LMM) cloned its causative gene, LMM22. Both dysfunction overexpression of LMM22 gave rise the hypersensitive response-like death, reactive oxygen species bursts, activated defence responses. encodes an active UBP that is...
SUMMARY Brassinosteroids (BRs) are a class of steroid phytohormones that control various aspects plant growth and development. Several transcriptional factors (TFs) have been suggested to play roles in BR signaling. However, their possible relationship remains largely unknown. Here, we identified rice mutant dwarf low‐tillering 2 ( dlt2 ) with altered architecture, increased grain width, reduced sensitivity. DLT2 encodes GIBBERELLIN INSENSITIVE (GAI)‐REPRESSOR OF GAI (RGA)‐SCARECROW (GRAS)...
Abstract Inherited non-hemolytic anemia is a group of rare bone marrow disorders characterized by erythroid defects. Although concerted efforts have been made to explore the underlying pathogenetic mechanisms these diseases, understanding causative mutations are still incomplete. Here we identify in diseased pedigree that gain-of-function mutation toll-like receptor 8 ( TLR8 ) implicated inherited anemia. expressed lineage and erythropoiesis impaired activation whereas enhanced inhibition...
A field experiment was conducted to investigate the effect of controlled-release fertilizer (CRF) combined with urea (UR) on soil fertility and environment in wheat-rice rotation system. Changes four forms nitrogen (total nitrogen, ammonium nitrate microbial biomass nitrogen) activities three enzymes participating transformation (urease, protease, reductase) were measured seven fertilization treatments (no fertilization, routine 10%CRF+90%UR, 20%CRF+80%UR, 40%CRF+60%UR, 80%CRF+20%UR,...
To examine the effects of pig manure application on dry matter production, nitrogen accumulation and distribution, grain yield use efficiency rice wheat, field trial was conducted with wheat 863 498. Fertilization treatments consisted seven rates organic supply: control (CK, no chemical fertilizer, manure), conventional fertilizing (T1, 2500 kg·hm-2 75% (T2), 5000 50% (T3), 10000 (T4), 15000 (T5) 20000 (T6). Combined fertilizer promoted throughout growing season. At maturity stage highest...