Haiyang Chang

ORCID: 0009-0006-9013-4425
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About
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Research Areas
  • T-cell and B-cell Immunology
  • Gallbladder and Bile Duct Disorders
  • Pediatric Hepatobiliary Diseases and Treatments
  • Aortic aneurysm repair treatments
  • Immune Cell Function and Interaction
  • Aortic Disease and Treatment Approaches
  • Biliary and Gastrointestinal Fistulas
  • Monoclonal and Polyclonal Antibodies Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Single-cell and spatial transcriptomics
  • Glycosylation and Glycoproteins Research
  • Cell Adhesion Molecules Research
  • Infectious Aortic and Vascular Conditions
  • vaccines and immunoinformatics approaches
  • Conducting polymers and applications
  • Cancer-related molecular mechanisms research
  • Advanced Memory and Neural Computing
  • Immunotherapy and Immune Responses
  • Renal and Vascular Pathologies
  • Transition Metal Oxide Nanomaterials
  • Cancer, Hypoxia, and Metabolism
  • Veterinary Oncology Research
  • Viral Infections and Vectors
  • Computational Geometry and Mesh Generation

University of Guelph
2020-2024

Ji Hua Laboratory
2024

Guangdong University of Technology
2024

Hunan Normal University
2023

Second Hospital of Shandong University
2015-2023

Shandong University
2015-2023

Weatherford College
2020

Versus Arthritis
2020

Shandong First Medical University
2015-2018

Jinan City People's Hospital
2018

The dog is valued as a companion animal and increasingly recognized model for human disorders. Given the importance of T cells in health disease, comprehensive knowledge canine can contribute to our understanding pathogenesis mechanisms inform development new treatment strategies. However, diversity still poorly understood mainly due lack species-reactive antibodies use flow cytometry. aim this study was generate detailed atlas peripheral blood TCRαβ + healthy dogs using single-cell...

10.3389/fimmu.2023.1123366 article EN cc-by Frontiers in Immunology 2023-02-23

Background The study was conducted to investigate the effectiveness and cost of computed tomography (CT)‐guided percutaneous microwave ablation (MWA) thoracoscopic lobectomy for stage I non‐small cell lung cancer (NSCLC). Methods We retrospectively analyzed data 46 85 patients with NSCLC treated CT‐guided MWA or lobectomy, respectively, at our center from July 2013 June 2015. Overall survival (OS), disease‐free (DFS), local control rate, hospital stay, were evaluated. Survival curves...

10.1111/1759-7714.12842 article EN cc-by-nc Thoracic Cancer 2018-08-28

With the rapid development of information, energy, and materials industries in China, demand for high-performance polymers is gradually increasing. Photosensitive polyimide (PSPI) has emerged as an ideal choice optoelectronic due to its outstanding thermal stability, mechanical strength, low dielectric constant. In particular, bio-based photosensitive prepared from chemicals, a green polymer material, not only reflects advantages environmental protection resource efficiency but also...

10.1155/2024/5541865 article EN cc-by International Journal of Optics 2024-03-01

To evaluate the clinical efficacy and safety of an innovative percutaneous transhepatic extraction balloon dilation (PTEBD) technique for clearance gallbladder stones in patients with concomitant common bile duct (CBD).The data from 17 consecutive who underwent PTEBD were retrospectively analyzed. After removal CBD by (PTBD), extracted to pushed into duodenum a after sphincter Oddi. Large fragmented using metallic basket. The monitored immediate adverse events including hemorrhage,...

10.3748/wjg.v24.i33.3799 article EN cc-by-nc World Journal of Gastroenterology 2018-09-06

Abstract To compare the diagnostic performance of percutaneous transhepatic cholangiography and endoscopic retrograde for pathological assessment suspected malignant bile duct stricture, using brush cytology forceps biopsy. The study group comprised 79 consecutive patients who underwent biliary 38 whom (group A) other 41 B). sensitivity, specificity, positive predictive value, negative accuracy were calculated. A subset analysis was performed to determine effect location type stricture on...

10.1097/md.0000000000019545 article EN cc-by-nc Medicine 2020-03-01

A D–A conjugated polymer was used in fabrication of memory devices. However, devices using polymers as active layers alone do not lead to satisfactory results. In this paper, we have synthesized a donor–acceptor by the Suzuki coupling reaction. The prepared exhibit ternary behavior. MoO3 nanoparticles large number oxygen vacancies on their surface that can act charge traps. (NPs) are mixed with prepare for improved performance. relationship between mass percentage NPs and storage performance...

10.1021/acs.jpcc.4c00703 article EN The Journal of Physical Chemistry C 2024-04-11

The domestic cat (Felis catus) is a valued companion animal and model for virally induced cancers immunodeficiencies. However, species-specific limitations such as scarcity of immune cell markers constrain our ability to resolve subsets at sufficient detail. goal this study was characterize circulating feline T cells other leukocytes based on their transcriptomic landscape T-cell receptor repertoire using single RNA-sequencing.

10.1101/2024.05.21.595010 preprint EN 2024-05-21

Purpose: To evaluate the outcomes of percutaneous intervention (PI) for transplant renal artery stenosis (TRAS). Materials and Methods: Doppler ultrasonography was used as screening tool, angiography diagnostic method TRAS. The indications PI were (1) a reduction in lumen diameter >50% or (2) mean pressure gradient >15 mm Hg. Technical success assessed immediately after procedure. short-term results evaluated by serum creatinine (Scr) levels blood (BP). long-term graft survival...

10.1177/1538574416682157 article EN Vascular and Endovascular Surgery 2016-12-19

To investigate the safety and efficacy of homemade fenestration chimney techniques for left subclavian artery (LSA) revascularization during zone 2 thoracic endovascular aortic repair (TEVAR).From February 2017 to 2021, 41 patients undergoing technique (group A) 42 B) preserve LSA TEVAR were enrolled in present study. The procedure was indicated dissections with unsuitable proximal landing refractory pain hypertension, rupture malperfusion, high-risk radiographic features. baseline...

10.3389/fcvm.2023.1144751 article EN cc-by Frontiers in Cardiovascular Medicine 2023-05-31

Radiofrequency ablation (RFA), an established and minimally invasive therapy for hepatocellular carcinoma, has become important treatment strategy. However, tumor aggressiveness remains a common problem. The epithelial-mesenchymal transition (EMT) is thought to play role in this process.Due limited sample volumes harvested from patients, we heat-treated cell line mouse model investigate the mechanisms of incomplete EMT.We H22 HepG2 cells using water bath determine suitable temperature RFA....

10.4103/jcrt.jcrt_12_20 article EN Journal of Cancer Research and Therapeutics 2020-01-01

The purpose of this study was to evaluate the efficacy and safety zone 2 thoracic endovascular aortic repair assisted by chimney technique or single-branched stent graft for preservation left subclavian artery, summarize our single-center experience with techniques.From February 2017 June 2020, 137 patients who underwent artery revascularization during were enrolled. Patients had acute type B dissection penetrating ulcer associated intramural hematoma. performed in 68 (group A), deployed 69...

10.1177/15266028221102657 article EN Journal of Endovascular Therapy 2022-06-09

Objective This study was performed to analyze the long-term follow-up safety and efficacy of transcatheter dense coil embolization for splenic artery aneurysms. Methods Thirty-two patients (18 women, 14 men; age range, 23–56 years; mean age, 43.1 ± 13.6 years) who underwent treatment aneurysms from August 2010 January 2018 were retrospectively reviewed. The size location aneurysms, technical clinical outcomes procedure, complications related procedure Results success rate 100% (mean aneurysm...

10.1177/0300060519873256 article EN cc-by-nc Journal of International Medical Research 2019-09-11

To evaluate the effectiveness and safety of combined ursodeoxycholic acid percutaneous transhepatic balloon dilation for management gallstones after expulsion common bile duct (CBD) stones.From April 2014 to May 2016, 15 consecutive patients (6 men 9 women) aged 45-86 (mean, 69.07 ± 9.91) years suffering from CBD stones associated with were evaluated. Good gallbladder contraction function was confirmed by type B ultrasonography. Dilation cystic detected. Percutaneous papilla performed,...

10.3748/wjg.v24.i39.4489 article EN cc-by-nc World Journal of Gastroenterology 2018-10-19

A 61-year-old man presented with upper abdominal pain and jaundice. Abdominal computed tomography imaging revealed stones in the gallbladder common bile duct, a thickening of wall an obvious increase volume gallbladder. Initial treatment using endoscopic retrograde cholangiopancreatography failed due to presence surgically altered gastrointestinal anatomy. Stones duct were subsequently removed concurrently via percutaneous transhepatic papilla balloon dilatation combined transcystic...

10.1097/md.0000000000007964 article EN cc-by-nc Medicine 2017-08-29

Rationale: Pulmonary embolization is a life-threatening condition. The deployment of inferior vena cava (IVC) filter the first choice for preventing embolus from lower extremity. However, IVC complications are rare but not to be neglected. Penetration arterial wall may result in catastrophic damages. This case report describes woman who suffered retroperitoneal hemorrhage after placement an due pulmonary embolization. Her was found have penetrated right lumbar artery and caused massive...

10.1097/md.0000000000009618 article EN cc-by-nc Medicine 2018-01-01

Donor–acceptor (D–A) conjugated polymers have exhibited their utility in the fabrication of memory devices with high information storage capacity. The device performance can be effectively regulated through appropriate pairing acceptor and donor moieties. Six different D–A polymers, featuring varied structures, were synthesized by using Suzuki coupling reaction. Donor molecules such as fluorene, carbazole, 4′-methoxytriphenylamine, well molecule dipyrido[3,2-a:2′,3′-c]phenazine (dppz),...

10.1021/acsapm.4c01091 article EN ACS Applied Polymer Materials 2024-08-06

Abstract Background Lymphocytic neoplasms with frequent reactive lymphocytes are uncommonly reported in dogs, and can pose a diagnostic challenge. Different modalities such as cytology, flow cytometry, histopathology, immunohistochemistry, clonality testing, sometimes required for diagnosis. This report illustrates the value of using multi-modal approach to decipher complex lymphocytic tumor, introduces immune repertoire sequencing adjunct. Case presentation A 10-month-old Great Dane was...

10.1186/s12917-021-02783-3 article EN cc-by BMC Veterinary Research 2021-02-18

Introduction The domestic cat (Felis catus) is a valued companion animal and model for virally induced cancers immunodeficiencies. However, species-specific limitations such as scarcity of immune cell markers constrain our ability to resolve subsets at sufficient detail. goal this study was characterize circulating feline T cells other leukocytes based on their transcriptomic landscape T-cell receptor repertoire using single RNA-sequencing. Methods Peripheral blood from 4 healthy cats...

10.3389/fimmu.2024.1438004 article EN cc-by Frontiers in Immunology 2024-11-15

All-inorganic halide perovskite (CsPbX3) nanocrystals (NCs) have garnered significant attention due to their excellent photoelectric properties. However, practical application has been limited by stability issues. This study presents a strategy combining physical confinement through carrier matrix and chemical bond coupling enhance the of CsPbX3 NCs significantly under UV irradiation, polar solvents, thermal conditions. Specifically, CsPbBr3 exhibited near-complete fluorescence quenching...

10.1021/acsanm.4c05252 article EN ACS Applied Nano Materials 2024-11-26
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