A5110576945- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Random lasers and scattering media
- Photoacoustic and Ultrasonic Imaging
- Advanced X-ray and CT Imaging
- Optical Imaging and Spectroscopy Techniques
- Advanced Optical Sensing Technologies
- Advanced MRI Techniques and Applications
- Image Processing Techniques and Applications
- Advanced Fluorescence Microscopy Techniques
- Cardiac Imaging and Diagnostics
- Optical Coherence Tomography Applications
- Infrared Thermography in Medicine
- Digital Holography and Microscopy
- Computer Graphics and Visualization Techniques
- Ocular and Laser Science Research
- MRI in cancer diagnosis
- Digital Radiography and Breast Imaging
- Advanced Optical Imaging Technologies
- Ultrasound and Hyperthermia Applications
- Advanced Radiotherapy Techniques
- Ultrasound and Cavitation Phenomena
- Optimal Power Flow Distribution
- Ferroptosis and cancer prognosis
- Radiation Dose and Imaging
Soochow University
2024-2025
First Affiliated Hospital of Soochow University
2024-2025
Jinan University
2023-2024
Shandong First Medical University
2023
Affiliated Hospital of Taishan Medical University
2023
United Imaging Healthcare (China)
2016-2022
Resonance Research (United States)
2021
University of Minnesota
2021
First Affiliated Hospital of Nanchang University
2021
Nanchang University
2021
The world’s first total-body PET scanner with an axial field of view (AFOV) 194 cm is now in clinical and research use at our institution. uEXPLORER PET/CT system the commercially available scanner. Here we present a detailed physical characterization this based on National Electrical Manufacturers Association (NEMA) NU 2-2018 along new set measurements devised to appropriately characterize AFOV. <b>Methods:</b> Sensitivity, count-rate performance, time-of-flight resolution, spatial image...
The world's first 194-cm-long total-body PET/CT scanner (uEXPLORER) has been built by the EXPLORER Consortium to offer a transformative platform for human molecular imaging in clinical research and health care. Its coverage ultra-high sensitivity provide opportunities more accurate tracer kinetic analysis studies of physiology, biochemistry, pharmacology. objective this study was demonstrate capability parametric quantify improvement image quality parameter estimation direct kernel...
In this Letter, we propose a single-pixel imaging method that can reproduce high-quality full-color images in real time. The is based on 3-step phase-shifting structured-illumination-based Fourier (FSI). To acquire the desired color information, adopt time-division-multiplexing illumination by using red, green, blue, and white (RGBW) 4-chip light-emitting diode (LED). Every single chip LED be controlled individually. With LED, novel, to best of our knowledge, strategy, termed complex...
Abstract Abnormal metabolic reprogramming is essential for tumorigenesis, metastasis, and the regulation of immune responses. Fatty acid synthase (FASN), a key enzyme in lipid metabolism, plays crucial role these processes. However, relationship between FASN-mediated response colorectal cancer (CRC) remains unclear. The present study demonstrated that FASN expression elevated CRC tissues significantly associated with poor prognosis. Functional experiments revealed promotes proliferation,...
Angiogenesis plays an important role in tumor growth and expansion, which makes it one of the most critical subjects oncologic research. can be imaged with photoacoustic microscopy (PAM), however lateral resolution deteriorates significantly out focus. Virtual-point-detector-based synthetic aperture focusing technique (SAFT) combined coherence weighting factor (CF) alleviate blurring, at a cost anisotropy resolution. In this study, two-dimensional SAFT CF was investigated to improve yield...
To improve the lateral resolution of blood vessels along arbitrary direction out focus in photoacoustic microscopy (PAM), we propose an adaptive synthetic-aperture focusing technique (ASAFT) for microvasculature imaging which can be automatically applied to each branch vessels, based on our previous two-dimensional (2D) SAFT. The ASAFT is validated both phantom study and vivo imaging. results demonstrate that provide images with better at different depths various directions compared...
Autofocusing is widely used in applications where sharp image acquisition or projection needed. Here we report an active autofocusing method for projection. The works with wide-field structured illumination and single-pixel detection. To find the focus position, illuminates target object a set of 3-step phase-shifting Fourier basis patterns repeatedly collects backscattered light by using detector through grating. Dual modulation-dynamic modulation time-varying static grating-embeds depth...
Single-pixel microscopy enables observation of micro samples in invisible wave bands. Finding the focus position is essential to capture a clear image sample but could be difficult for single-pixel particularly It because structured patterns projected onto would and searching manually exhausting. Here, we report an autofocus method Fourier microscopy. The reported allows one find without recording or reconstructing complete image. determined by magnitude summation small number coefficients,...
Stroke is a devastating disease. The changes in cerebral hemodynamics and oxygen metabolism associated with stroke play an important role pathophysiology study. But the were difficult to describe single imaging modality. Here blood flow (CBF), volume (CBV), saturation (SO2) yielded laser speckle (LSI) photoacoustic microscopy (PAM) during after 3-h acute focal ischemic rats. These hemodynamic measures further synthesized deduce extraction fraction (OEF). results indicate that all except CBV...
Abstract Background Disulfidptosis and Ferroptosis are two novel forms of cell death. Although their mechanisms differ, research has shown that there is a relationship between the two. Investigating connection these death can further deepen our understanding development progression cancer, provide better prediction models for accurate prognosis. Methods In this study, RNA sequencing (RNA-seq) data, clinical single nucleotide polymorphism (SNP) single-cell data were obtained from public...
Late gadolinium enhancement (LGE) cardiac MRI (CMR) is the clinical standard for diagnosis of myocardial scar. 3D isotropic LGE CMR provides improved coverage and resolution compared to 2D imaging. However, image acceleration required due long scan times contrast washout. Physics-guided deep learning (PG-DL) approaches have recently emerged as an accelerated strategy. Training PG-DL methods typically performed in a supervised manner requiring fully-sampled data, which challenging CMR....
Lesion segmentation is one of the crucial steps for computerized dermoscopy image analysis. To accurately extract lesion borders from images, a novel method based on fully convolutional neural network proposed in this paper. The designed contains low-level trunk followed by two brunches (global brunch and local brunch). fine-tuned VGG16 net. Two with different receptive fields global features respectively. After combination features, final results are obtained through pixel-wise softmax...
Collecting and mining customer consumption data are crucial to assess value predict behaviors. This paper proposes a new procedure, based on an improved Random Forest Model by: adding indicator, joining the RFMS-based method K-means algorithm with Entropy Weight Method applied in computing index, classifying customers different categories, then constructing forecasting model whose RMSE is smallest all kinds of models. The results show that identifying by this RMF index facilitates profiling,...
This study investigated the outcomes and major adverse cardiovascular events (MACEs) incurred by acute myocardial infarction (AMI) patients comorbiding with hypertension hyperhomocysteinemia (HHcy) during hospitalization 1-year follow-up. 648 consecutive AMI were divided into four categories: (1) Hcy ≥ 15 µmol/L; (2) < (3) no-hypertension (4) µmol/L. Information taken from these case files included gender, past medical history, vital signs, laboratory examination, electrocardiogram, coronary...
Because cerebral hypoperfusion brings damage to the brain, prevention of cerebrovascular diseases correlative by studying animal models makes great sense. Since complicated adaptive changes in could not be revealed only blood flow (CBF) velocity imaging, we performed multi-parameter imaging combining laser speckle and functional photoacoustic microscopy. The CBF, hemoglobin oxygen saturation (SO2), total concentration (HbT) single vessels ipsilateral cortex were observed during transient...
Data-driven respiratory gating was previous developed to extract information directly from PET listmode data. It also shown that different regions may contribute differently the accuracy of motion signal, affecting successful rate this method. The goal study is develop and evaluate methods automatically determine optimum acquire signal. Maximum likely annihilation point used map each event 3D volume space. Parametric-based interests (VOI) for selection events. For a fixed VOI, center mass...